DUS3L (dihydrouridine synthase 3 like)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: DUS3L (dihydrouridine synthase 3 like) Homo sapiens

Analyze

Symbol:

DUS3L

Name:

dihydrouridine synthase 3 like

RGD ID:

1604330

HGNC Page

HGNC:26920

Description:

Enables mRNA dihydrouridine synthase activity and tRNA dihydrouridine synthase activity. Involved in regulation of translation and tRNA dihydrouridine synthesis.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

dihydrouridine synthase 3-like; DUS3; FLJ13896; mRNA-dihydrouridine synthase DUS3L; tRNA-dihydrouridine synthase 3-like; tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like

RGD Orthologs

Mouse

Rat

Chinchilla

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Dus3l (dihydrouridine synthase 3-like (S. cerevisiae))	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Dus3l (dihydrouridine synthase 3-like)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Chinchilla lanigera (long-tailed chinchilla):	Dus3l (dihydrouridine synthase 3 like)	NCBI	Ortholog
Canis lupus familiaris (dog):	DUS3L (dihydrouridine synthase 3 like)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dus3l (dihydrouridine synthase 3 like)	NCBI	Ortholog
Sus scrofa (pig):	DUS3L (dihydrouridine synthase 3 like)	HGNC	EggNOG, Ensembl, NCBI, OMA, OrthoDB, Panther, Treefam
Chlorocebus sabaeus (green monkey):	DUS3L (dihydrouridine synthase 3 like)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Dus3l (dihydrouridine synthase 3 like)	NCBI	Ortholog
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Dus3l (dihydrouridine synthase 3-like)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dus3l (dihydrouridine synthase 3-like (S. cerevisiae))	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	dus3l (dihydrouridine synthase 3-like (S. cerevisiae))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	CG10463	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	DUS3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y37E11B.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	5,785,140 - 5,791,163 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	19	5,784,832 - 5,791,225 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	5,785,151 - 5,791,174 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	5,736,151 - 5,742,192 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	5,723,144 - 5,730,021 (-)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	5,546,085 - 5,552,589 (-)	NCBI		HuRef
CHM1_1	19	5,785,079 - 5,791,308 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	5,771,937 - 5,778,591 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-methylcholine (EXP)

acrylamide (ISO)

antirheumatic drug (EXP)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

caffeine (EXP)

choline (ISO)

clothianidin (EXP)

coumarin (EXP)

cyclosporin A (EXP,ISO)

decabromodiphenyl ether (ISO)

diethyl maleate (ISO)

enzyme inhibitor (EXP)

ethanol (ISO)

folic acid (ISO)

L-methionine (ISO)

paracetamol (ISO)

perfluorononanoic acid (EXP)

progesterone (EXP)

sodium arsenite (EXP)

Soman (ISO)

tamoxifen (ISO)

tetrachloroethene (ISO)

trichostatin A (EXP)

valproic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mRNA processing (IEA)

regulation of translation (IDA)

tRNA dihydrouridine synthesis (IDA,IEA,IMP)

tRNA processing (IEA)

Molecular Function

flavin adenine dinucleotide binding (IEA)

metal ion binding (IEA)

mRNA dihydrouridine synthase activity (IDA)

oxidoreductase activity (IEA)

protein binding (IPI)

RNA binding (HDA)

tRNA dihydrouridine synthase activity (IBA,IDA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8125298	PMID:12477932	PMID:14702039	PMID:15489334	PMID:16344560	PMID:21832049	PMID:21873635	PMID:22681889	PMID:22863883	PMID:24104479	PMID:24163370	PMID:24623722
PMID:26186194	PMID:26344197	PMID:28514442	PMID:29229926	PMID:29467282	PMID:29845934	PMID:30561431	PMID:31091453	PMID:31586073	PMID:32203420	PMID:32572027	PMID:32814053
PMID:33742100	PMID:33961781	PMID:34011540	PMID:34556860	PMID:34798057	PMID:35256949	PMID:35271311	PMID:35384245	PMID:35439318	PMID:35563538	PMID:35944360

Genomics

Comparative Map Data

DUS3L
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	5,785,140 - 5,791,163 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	19	5,784,832 - 5,791,225 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	5,785,151 - 5,791,174 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	5,736,151 - 5,742,192 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	5,723,144 - 5,730,021 (-)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	5,546,085 - 5,552,589 (-)	NCBI		HuRef
CHM1_1	19	5,785,079 - 5,791,308 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	5,771,937 - 5,778,591 (-)	NCBI		T2T-CHM13v2.0

Dus3l
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	57,069,224 - 57,077,093 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	57,071,757 - 57,077,093 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	56,764,751 - 56,770,093 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	56,764,757 - 56,770,093 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	56,904,174 - 56,909,516 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	56,449,902 - 56,454,965 (+)	NCBI		MGSCv36	mm8
Celera	17	61,108,892 - 61,114,234 (+)	NCBI		Celera
Cytogenetic Map	17	D	NCBI

Dus3l
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	1,593,491 - 1,598,663 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	1,594,123 - 1,598,655 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	2,028,265 - 2,032,806 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	9	7,377,380 - 7,381,917 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	9	6,333,460 - 6,338,001 (+)	NCBI	Rnor_WKY
Rnor_6.0	9	10,289,440 - 10,294,213 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	10,289,446 - 10,293,980 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	9,286,520 - 9,291,291 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	9	6,918,090 - 6,922,626 (-)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

Dus3l
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	3,653,257 - 3,660,331 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	3,653,613 - 3,660,331 (+)	NCBI	ChiLan1.0	ChiLan1.0

DUS3L
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	54,250,369 - 54,255,981 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	54,250,871 - 54,255,995 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	53,977,808 - 53,983,421 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	54,902,723 - 54,908,336 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	54,903,204 - 54,908,350 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	53,969,030 - 53,974,635 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	54,449,603 - 54,455,181 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	54,646,813 - 54,652,426 (+)	NCBI		UU_Cfam_GSD_1.0

Dus3l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	214,497,957 - 214,502,948 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	3,331,904 - 3,337,277 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936588	3,331,563 - 3,337,276 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DUS3L
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	73,197,669 - 73,204,977 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	73,197,614 - 73,202,676 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	73,719,549 - 73,724,598 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DUS3L
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	5,430,558 - 5,437,638 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	5,430,580 - 5,437,452 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666081	2,627,456 - 2,630,452 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dus3l
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	4,431,167 - 4,437,365 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	4,431,172 - 4,437,459 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 19p13.3-13.2(chr19:1972245-9648879)x3	copy number gain	See cases [RCV000052879]	Chr19:1972245..9648879 [GRCh38] Chr19:1972244..9759555 [GRCh37] Chr19:1923244..9620555 [NCBI36] Chr19:19p13.3-13.2	pathogenic
GRCh38/hg38 19p13.3-13.2(chr19:4039158-9176125)x3	copy number gain	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052881]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052881]\|See cases [RCV000052881]	Chr19:4039158..9176125 [GRCh38] Chr19:4039156..9286801 [GRCh37] Chr19:3990156..9147801 [NCBI36] Chr19:19p13.3-13.2	pathogenic
GRCh38/hg38 19p13.3(chr19:4934885-6501642)x3	copy number gain	See cases [RCV000052882]	Chr19:4934885..6501642 [GRCh38] Chr19:4934897..6501653 [GRCh37] Chr19:4885897..6452653 [NCBI36] Chr19:19p13.3	pathogenic
GRCh38/hg38 19p13.3-13.2(chr19:265917-8564134)x3	copy number gain	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052876]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052876]\|See cases [RCV000052876]	Chr19:265917..8564134 [GRCh38] Chr19:265917..8629018 [GRCh37] Chr19:216917..8535018 [NCBI36] Chr19:19p13.3-13.2	pathogenic
GRCh38/hg38 19p13.3(chr19:259395-6795611)x3	copy number gain	See cases [RCV000142627]	Chr19:259395..6795611 [GRCh38] Chr19:259395..6795622 [GRCh37] Chr19:210395..6746622 [NCBI36] Chr19:19p13.3	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3	copy number gain	See cases [RCV000511289]	Chr19:260912..58956888 [GRCh37] Chr19:19p13.3-q13.43	pathogenic\|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)	copy number gain	See cases [RCV000512296]	Chr19:260912..58956888 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19p13.3-13.2(chr19:3120160-9732820)x3	copy number gain	not provided [RCV000684096]	Chr19:3120160..9732820 [GRCh37] Chr19:19p13.3-13.2	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3	copy number gain	not provided [RCV000752444]	Chr19:260912..59097160 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3	copy number gain	not provided [RCV000752439]	Chr19:68029..59110290 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19p13.3(chr19:5455422-5995450)x3	copy number gain	not provided [RCV000740012]	Chr19:5455422..5995450 [GRCh37] Chr19:19p13.3	benign
GRCh37/hg19 19p13.3(chr19:5543902-5787595)x3	copy number gain	not provided [RCV000740015]	Chr19:5543902..5787595 [GRCh37] Chr19:19p13.3	benign
GRCh37/hg19 19p13.3(chr19:5655792-5867913)x3	copy number gain	not provided [RCV000740016]	Chr19:5655792..5867913 [GRCh37] Chr19:19p13.3	benign
NC_000019.9:g.(?_5678562)_(5903719_?)dup	duplication	not provided [RCV002239957]	Chr19:5678562..5903719 [GRCh37] Chr19:19p13.3	uncertain significance
NC_000019.9:g.(?_5678562)_(5897028_?)dup	duplication	not provided [RCV001918791]	Chr19:5678562..5897028 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.520G>A (p.Gly174Ser)	single nucleotide variant	Inborn genetic diseases [RCV002729997]	Chr19:5789587 [GRCh38] Chr19:5789598 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.698G>A (p.Arg233His)	single nucleotide variant	Inborn genetic diseases [RCV002687726]	Chr19:5789409 [GRCh38] Chr19:5789420 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.1523G>A (p.Arg508His)	single nucleotide variant	Inborn genetic diseases [RCV002794170]	Chr19:5786506 [GRCh38] Chr19:5786517 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.1822C>T (p.Arg608Cys)	single nucleotide variant	Inborn genetic diseases [RCV002687806]	Chr19:5785441 [GRCh38] Chr19:5785452 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.767G>A (p.Arg256Lys)	single nucleotide variant	Inborn genetic diseases [RCV002992916]	Chr19:5789340 [GRCh38] Chr19:5789351 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.982G>A (p.Gly328Arg)	single nucleotide variant	Inborn genetic diseases [RCV002688441]	Chr19:5788137 [GRCh38] Chr19:5788148 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.986C>T (p.Ala329Val)	single nucleotide variant	Inborn genetic diseases [RCV002758679]	Chr19:5788133 [GRCh38] Chr19:5788144 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.1876A>C (p.Ile626Leu)	single nucleotide variant	Inborn genetic diseases [RCV003000601]	Chr19:5785387 [GRCh38] Chr19:5785398 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.1838C>T (p.Thr613Met)	single nucleotide variant	Inborn genetic diseases [RCV002951034]	Chr19:5785425 [GRCh38] Chr19:5785436 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.1478C>T (p.Pro493Leu)	single nucleotide variant	Inborn genetic diseases [RCV002984149]	Chr19:5786757 [GRCh38] Chr19:5786768 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.435C>G (p.His145Gln)	single nucleotide variant	Inborn genetic diseases [RCV002767715]	Chr19:5789672 [GRCh38] Chr19:5789683 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.700C>T (p.Arg234Trp)	single nucleotide variant	Inborn genetic diseases [RCV002768066]	Chr19:5789407 [GRCh38] Chr19:5789418 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.911G>A (p.Arg304His)	single nucleotide variant	Inborn genetic diseases [RCV002666053]	Chr19:5788388 [GRCh38] Chr19:5788399 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.229C>G (p.Leu77Val)	single nucleotide variant	Inborn genetic diseases [RCV002696895]	Chr19:5790205 [GRCh38] Chr19:5790216 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.155A>C (p.Lys52Thr)	single nucleotide variant	Inborn genetic diseases [RCV002988985]	Chr19:5790279 [GRCh38] Chr19:5790290 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.397G>A (p.Ala133Thr)	single nucleotide variant	Inborn genetic diseases [RCV002920011]	Chr19:5789710 [GRCh38] Chr19:5789721 [GRCh37] Chr19:19p13.3	uncertain significance
NM_020175.3(DUS3L):c.1715G>A (p.Arg572Gln)	single nucleotide variant	Inborn genetic diseases [RCV002987911]	Chr19:5785639 [GRCh38] Chr19:5785650 [GRCh37] Chr19:19p13.3	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	4760
Count of miRNA genes:	994
Interacting mature miRNAs:	1245
Transcripts:	ENST00000309061, ENST00000320699, ENST00000585587, ENST00000589085, ENST00000589841, ENST00000589854, ENST00000590087, ENST00000590110, ENST00000590343, ENST00000590681, ENST00000591560, ENST00000592468, ENST00000592491, ENST00000592673, ENST00000593229
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

RH98517

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	19	5,785,203 - 5,785,449	UniSTS	GRCh37
Build 36	19	5,736,203 - 5,736,449	RGD	NCBI36
Celera	19	5,723,196 - 5,723,442	RGD
Cytogenetic Map	19	p13.3	UniSTS
HuRef	19	5,546,137 - 5,546,383	UniSTS
GeneMap99-GB4 RH Map	19	34.07	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

visual system

adipose tissue

appendage

entire extraembryonic component

pharyngeal arch

High

Medium

2358

1746

1542

455

1330

298

3927

1376

2049

299

1421

1540

170

1186

2373

Low

1245

184

169

621

167

429

821

1685

120

415

Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001161619	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_020175	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017027020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047439111	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002958335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_244033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_936193	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC011499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF074704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF091072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK023958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK225840	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK297037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK315691	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL365411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC004549	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC008362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC009973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA839738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENST00000309061 ⟹ ENSP00000311977

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,785,140 - 5,791,163 (-)	Ensembl

RefSeq Acc Id:

ENST00000320699 ⟹ ENSP00000315558

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,785,140 - 5,791,206 (-)	Ensembl

RefSeq Acc Id:

ENST00000585587 ⟹ ENSP00000468233

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,789,251 - 5,790,954 (-)	Ensembl

RefSeq Acc Id:

ENST00000589085

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,785,140 - 5,791,210 (-)	Ensembl

RefSeq Acc Id:

ENST00000589841

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,785,456 - 5,785,999 (-)	Ensembl

RefSeq Acc Id:

ENST00000589854

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,789,937 - 5,791,210 (-)	Ensembl

RefSeq Acc Id:

ENST00000590087

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,787,247 - 5,788,170 (-)	Ensembl

RefSeq Acc Id:

ENST00000590110 ⟹ ENSP00000465369

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,788,024 - 5,791,225 (-)	Ensembl

RefSeq Acc Id:

ENST00000590343 ⟹ ENSP00000466351

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,784,832 - 5,785,755 (-)	Ensembl

RefSeq Acc Id:

ENST00000590681

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,789,294 - 5,791,038 (-)	Ensembl

RefSeq Acc Id:

ENST00000591560 ⟹ ENSP00000467987

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,785,456 - 5,788,176 (-)	Ensembl

RefSeq Acc Id:

ENST00000592468 ⟹ ENSP00000468075

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,785,456 - 5,788,034 (-)	Ensembl

RefSeq Acc Id:

ENST00000592491 ⟹ ENSP00000467302

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,789,134 - 5,790,265 (-)	Ensembl

RefSeq Acc Id:

ENST00000592673

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,785,464 - 5,786,930 (-)	Ensembl

RefSeq Acc Id:

ENST00000593229

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	19	5,787,556 - 5,788,122 (-)	Ensembl

RefSeq Acc Id:

NM_001161619 ⟹ NP_001155091

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	5,785,140 - 5,791,163 (-)	NCBI
GRCh37	19	5,785,151 - 5,791,249 (-)	RGD
Celera	19	5,723,144 - 5,730,021 (-)	RGD
HuRef	19	5,546,085 - 5,552,589 (-)	ENTREZGENE
CHM1_1	19	5,785,079 - 5,791,308 (-)	NCBI
T2T-CHM13v2.0	19	5,771,937 - 5,778,591 (-)	NCBI

Sequence:

show sequence

AGAGCGGATGTGAGGGGCGCCGATGGCGGAGGGAACGGCGGAGGCTCCTCTAGAGAATGGTGGT
GGTGGCGACTCGGGAGCCGGAGCTTTGGAACGAGGAGTGGCGCCCATTAAGCGTCAATACCTCA
CCACCAAGGAGCAGTTTCACCAATTCCTGGAAGCCAAAGGGCAGGAGAAGACTTGCCGGGAAAC
CGAGCTGGACATCCGTGGCAAACTTTACCTGGCCCCCCTCACCACGTGTGGGAACCTGCCCTTC
CGACGGATCTGCAAGCGCTTCGGGGCGGATGTGACATGTGGAGAGATGGCCGTCTGCACCAACC
TGCTGCAGGGCCAGATGTCCGAGTGGGCCCTACTCAAACGCCACCAGTGTGAGGACATCTTTGG
CGTCCAGCTGGAGGGCGCCTTCCCCGACACCATGACCAAGTGTGCCGAGCTGCTGAGCCGCACC
GTGGAGGTGGACTTTGTGGACATCAACGTCGGCTGCCCCATCGACCTCGTGTACAAGAAGGGTG
GGGGCTGTGCCCTCATGAATCGCTCCACCAAGTTCCAGCAGATCGTCCGTGGCATGAACCAGGT
GCTGGATGTGCCGCTGACTGTGAAGATCCGCACAGGCGTCCAGGAGCGTGTGAACCTGGCGCAC
CGCCTGCTGCCCGAGCTGCGGGACTGGGGCGTGGCACTCGTCACGCTCCACGGCCGCTCTCGGG
AGCAGCGCTACACCAAGCTAGCCGACTGGCAGTACATCGAGGAGTGCGTGCAGGCCGCCAGCCC
CATGCCCCTGTTCGGAAATGGGGACATCTTGTCATTTGAGGATGCCAACCGCGCCATGCAGACT
GGTGTCACCGGGATCATGATTGCCCGTGGCGCCCTGCTCAAGCCGTGGCTCTTCACGGAGATCA
AGGAGCAGCGGCACTGGGACATCTCGTCGTCCGAGCGCCTGGACATCCTGCGGGACTTCACCAA
CTACGGCCTGGAGCACTGGGGCTCGGACACGCAGGGCGTGGAGAAGACCCGGCGCTTTCTGCTC
GAGTGGCTGTCCTTCCTGTGCCGGTACGTGCCCGTGGGGCTGCTGGAGCGGCTCCCACAGAGGA
TCAACGAGCGGCCGCCCTACTACCTGGGCCGCGACTACCTGGAGACGCTGATGGCCAGCCAGAA
GGCAGCCGACTGGATCCGCATCAGCGAGATGCTCCTTGGGCCAGTGCCCCCCAGCTTCGCCTTC
TTGCCGAAGCACAAGGCCAACGCGTACAAGTAGCCTCAGGCTTTCCCAGGGGCACCCTGGGGCG
AGGAGAGTACAATAAATTTTATTCTTTTAAAA

hide sequence

RefSeq Acc Id:

NM_020175 ⟹ NP_064560

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	5,785,140 - 5,791,163 (-)	NCBI
GRCh37	19	5,785,151 - 5,791,249 (-)	RGD
Build 36	19	5,736,151 - 5,742,192 (-)	NCBI Archive
Celera	19	5,723,144 - 5,730,021 (-)	RGD
HuRef	19	5,546,085 - 5,552,589 (-)	ENTREZGENE
CHM1_1	19	5,785,079 - 5,791,308 (-)	NCBI
T2T-CHM13v2.0	19	5,771,937 - 5,778,591 (-)	NCBI

Sequence:

show sequence

AGAGCGGATGTGAGGGGCGCCGATGGCGGAGGGAACGGCGGAGGCTCCTCTAGAGAATGGTGGT
GGTGGCGACTCGGGAGCCGGAGCTTTGGAACGAGGAGTGGCGCCCATTAAGCGTCAATACCTCA
CCACCAAGGAGCAGTTTCACCAATTCCTGGAAGCCAAAGGGCAGGAGAAGACTTGCCGGGAAAC
CGAGGTAGGAGACCCTGCTGGCAATGAGCTGGCTGAGCCTGAGGCTAAGCGGATCCGACTGGAG
GATGGACAGACGGCGGACGGGCAGACGGAGGAGGCAGCAGAGCCCGGGGAGCAGCTACAGACTC
AGAAGAGGGCCCGGGGACAAAACAAGGGCCGGCCCCATGTGAAGCCCACGAACTACGACAAGAA
CAGGCTGTGTCCCTCCCTAATCCAGGAGTCGGCTGCTAAGTGTTTCTTCGGTGATCGCTGCCGC
TTTCTGCACGACGTGGGGCGCTACCTGGAGACCAAGCCGGCCGACCTGGGCCCCCGCTGCGTGC
TCTTCGAGACCTTCGGCCGGTGCCCCTACGGCGTGACCTGCCGCTTCGCTGGGGCCCACCTGAG
GCCCGAGGGACAGAACCTGGTGCAGGAGGAGTTGGCGGCCCGCGGGACCCAGCCCCCGTCCATC
CGCAACGGCCTGGACAAAGCCCTGCAGCAGCAGCTGCGGAAGCGCGAGGTCCGCTTCGAGCGAG
CTGAGCAGGCCCTGCGCCGGTTCAGCCAGGGCCCCACACCCGCTGCCGCTGTCCCCGAGGGCAC
GGCAGCCGAGGGCGCTCCCAGGCAGGAAAACTGTGGTGCCCAGCAGGTCCCCGCAGGGCCGGGC
ACTAGCACCCCTCCCAGCAGCCCCGTGCGGACCTGCGGGCCCCTGACGGATGAGGACGTGGTCA
GGCTGCGGCCCTGTGAGAAGAAGCGGCTGGACATCCGTGGCAAACTTTACCTGGCCCCCCTCAC
CACGTGTGGGAACCTGCCCTTCCGACGGATCTGCAAGCGCTTCGGGGCGGATGTGACATGTGGA
GAGATGGCCGTCTGCACCAACCTGCTGCAGGGCCAGATGTCCGAGTGGGCCCTACTCAAACGCC
ACCAGTGTGAGGACATCTTTGGCGTCCAGCTGGAGGGCGCCTTCCCCGACACCATGACCAAGTG
TGCCGAGCTGCTGAGCCGCACCGTGGAGGTGGACTTTGTGGACATCAACGTCGGCTGCCCCATC
GACCTCGTGTACAAGAAGGGTGGGGGCTGTGCCCTCATGAATCGCTCCACCAAGTTCCAGCAGA
TCGTCCGTGGCATGAACCAGGTGCTGGATGTGCCGCTGACTGTGAAGATCCGCACAGGCGTCCA
GGAGCGTGTGAACCTGGCGCACCGCCTGCTGCCCGAGCTGCGGGACTGGGGCGTGGCACTCGTC
ACGCTCCACGGCCGCTCTCGGGAGCAGCGCTACACCAAGCTAGCCGACTGGCAGTACATCGAGG
AGTGCGTGCAGGCCGCCAGCCCCATGCCCCTGTTCGGAAATGGGGACATCTTGTCATTTGAGGA
TGCCAACCGCGCCATGCAGACTGGTGTCACCGGGATCATGATTGCCCGTGGCGCCCTGCTCAAG
CCGTGGCTCTTCACGGAGATCAAGGAGCAGCGGCACTGGGACATCTCGTCGTCCGAGCGCCTGG
ACATCCTGCGGGACTTCACCAACTACGGCCTGGAGCACTGGGGCTCGGACACGCAGGGCGTGGA
GAAGACCCGGCGCTTTCTGCTCGAGTGGCTGTCCTTCCTGTGCCGGTACGTGCCCGTGGGGCTG
CTGGAGCGGCTCCCACAGAGGATCAACGAGCGGCCGCCCTACTACCTGGGCCGCGACTACCTGG
AGACGCTGATGGCCAGCCAGAAGGCAGCCGACTGGATCCGCATCAGCGAGATGCTCCTTGGGCC
AGTGCCCCCCAGCTTCGCCTTCTTGCCGAAGCACAAGGCCAACGCGTACAAGTAGCCTCAGGCT
TTCCCAGGGGCACCCTGGGGCGAGGAGAGTACAATAAATTTTATTCTTTTAAAA

hide sequence

RefSeq Acc Id:

XM_017027020 ⟹ XP_016882509

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	5,785,140 - 5,791,163 (-)	NCBI

Sequence:

show sequence

AATCAGGGAAGACACGCGTGACCCGGAAGGTCTTCCCGCCACACTCCAGAGCGGATGTGAGGGG
CGCCGATGGCGGAGGGAACGGCGGAGGCTCCTCTAGAGAATGGTGGTGGTGGCGACTCGGGAGC
CGGAGCTTTGGAACGAGGAGTGGCGCCCATTAAGCGTCAATACCTCACCACCAAGGAGCAGTTT
CACCAATTCCTGGAAGCCAAAGGGCAGGAGAAGACTTGCCGGGAAACCGAGGTAGGAGACCCTG
CTGGCAATGAGCTGGCTGAGCCTGAGGCTAAGCGGATCCGACTGGAGGATGGACAGACGGCGGA
CGGGCAGACGGAGGAGGCAGCAGAGCCCGGGGAGCAGCTACAGACTCAGAAGAGGGCCCGGGGA
CAAAACAAGGGCCGGCCCCATGTGAAGCCCACGAACTACGACAAGAACAGGCTGTGTCCCTCCC
TAATCCAGGAGTCGGCTGCTAAGTGTTTCTTCGGTGATCGCTGCCGCTTTCTGCACGACGTGGG
GCGCTACCTGGAGACCAAGCCGGCCGACCTGGGCCCCCGCTGCGTGCTCTTCGAGACCTTCGGC
CGGTGCCCCTACGGCGTGACCTGCCGCTTCGCTGGGGCCCACCTGAGGCCCGAGGGACAGAACC
TGGTGCAGGAGGAGTTGGCGGCCCGCGGGACCCAGCCCCCGTCCATCCGCAACGGCCTGGACAA
AGCCCTGCAGCAGCAGCTGCGGAAGCGCGAGGTCCGCTTCGAGCGAGCTGAGCAGGCCCTGCGC
CGGTTCAGCCAGGGCCCCACACCCGCTGCCGCTGTCCCCGAGGGCACGGCAGCCGAGGGCGCTC
CCAGGCAGGAAAACTGTGGTGCCCAGCAGGTCCCCGCAGGGCCGGGCACTAGCACCCCTCCCAG
CAGCCCCGTGCGGACCTGCGGGCCCCTGACGGATGAGGACGTGGTCAGGCTGCGGCCCTGTGAG
AAGAAGCGGTGTGGGAACCTGCCCTTCCGACGGATCTGCAAGCGCTTCGGGGCGGATGTGACAT
GTGGAGAGATGGCCGTCTGCACCAACCTGCTGCAGGGCCAGATGTCCGAGTGGGCCCTACTCAA
ACGCCACCAGTGTGAGGACATCTTTGGCGTCCAGCTGGAGGGCGCCTTCCCCGACACCATGACC
AAGTGTGCCGAGCTGCTGAGCCGCACCGTGGAGGTGGACTTTGTGGACATCAACGTCGGCTGCC
CCATCGACCTCGTGTACAAGAAGGGTGGGGGCTGTGCCCTCATGAATCGCTCCACCAAGTTCCA
GCAGATCGTCCGTGGCATGAACCAGGTGCTGGATGTGCCGCTGACTGTGAAGATCCGCACAGGC
GTCCAGGAGCGTGTGAACCTGGCGCACCGCCTGCTGCCCGAGCTGCGGGACTGGGGCGTGGCAC
TCGTCACGCTCCACGGCCGCTCTCGGGAGCAGCGCTACACCAAGCTAGCCGACTGGCAGTACAT
CGAGGAGTGCGTGCAGGCCGCCAGCCCCATGCCCCTGTTCGGAAATGGGGACATCTTGTCATTT
GAGGATGCCAACCGCGCCATGCAGACTGGTGTCACCGGGATCATGATTGCCCGTGGCGCCCTGC
TCAAGCCGTGGCTCTTCACGGAGATCAAGGAGCAGCGGCACTGGGACATCTCGTCGTCCGAGCG
CCTGGACATCCTGCGGGACTTCACCAACTACGGCCTGGAGCACTGGGGCTCGGACACGCAGGGC
GTGGAGAAGACCCGGCGCTTTCTGCTCGAGTGGCTGTCCTTCCTGTGCCGGTACGTGCCCGTGG
GGCTGCTGGAGCGGCTCCCACAGAGGATCAACGAGCGGCCGCCCTACTACCTGGGCCGCGACTA
CCTGGAGACGCTGATGGCCAGCCAGAAGGCAGCCGACTGGATCCGCATCAGCGAGATGCTCCTT
GGGCCAGTGCCCCCCAGCTTCGCCTTCTTGCCGAAGCACAAGGCCAACGCGTACAAGTAGCCTC
AGGCTTTCCCAGGGGCACCCTGGGGCGAGGAGAGTACAATAAATTTTATTCTTTTAAAATCCA

hide sequence

RefSeq Acc Id:

XM_047439111 ⟹ XP_047295067

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	5,785,767 - 5,791,163 (-)	NCBI

RefSeq Acc Id:

XR_244033

RefSeq Status:

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	5,786,467 - 5,791,163 (-)	NCBI
GRCh37	19	5,785,151 - 5,791,249 (-)	NCBI

Sequence:

show sequence

AATCAGGGAAGACACGCGTGACCCGGAAGGTCTTCCCGCCACACTCCAGAGCGGATGTGAGGGG
CGCCGATGGCGGAGGGAACGGCGGAGGCTCCTCTAGAGAATGGTGGTGGTGGCGACTCGGGAGC
CGGAGCTTTGGAACGAGGAGTGGCGCCCATTAAGCGTCAATACCTCACCACCAAGGAGCAGTTT
CACCAATTCCTGGAAGCCAAAGGGCAGGAGAAGACTTGCCGGGAAACCGAGGTAGGAGACCCTG
CTGGCAATGAGCTGGCTGAGCCTGAGGCTAAGCGGATCCGACTGGAGGATGGACAGACGGCGGA
CGGGCAGACGGAGGAGGCAGCAGAGCCCGGGGAGCAGCTACAGACTCAGAAGAGGGCCCGGGGA
CAAAACAAGGGCCGGCCCCATGTGAAGCCCACGAACTACGACAAGAACAGGCTGTGTCCCTCCC
TAATCCAGGAGTCGGCTGCTAAGTGTTTCTTCGGTGATCGCTGCCGCTTTCTGCACGACGTGGG
GCGCTACCTGGAGACCAAGCCGGCCGACCTGGGCCCCCGCTGCGTGCTCTTCGAGACCTTCGGC
CGGTGCCCCTACGGCGTGACCTGCCGCTTCGCTGGGGCCCACCTGAGGCCCGAGGGACAGAACC
TGGTGCAGGAGGAGTTGGCGGCCCGCGGGACCCAGCCCCCGTCCATCCGCAACGGCCTGGACAA
AGCCCTGCAGCAGCAGCTGCGGAAGCGCGAGGTCCGCTTCGAGCGAGCTGAGCAGGCCCTGCGC
CGGTTCAGCCAGGGCCCCACACCCGCTGCCGCTGTCCCCGAGGGCACGGCAGCCGAGGGCGCTC
CCAGGCAGGAAAACTGTGGTGCCCAGCAGGTCCCCGCAGGGCCGGGCACTAGCACCCCTCCCAG
CAGCCCCGTGCGGACCTGCGGGCCCCTGACGGATGAGGACGTGGTCAGGCTGCGGCCCTGTGAG
AAGAAGCGGCTGGACATCCGTGGCAAACTTTACCTGGCCCCCCTCACCACGTGTGGGAACCTGC
CCTTCCGACGGATCTGCAAGCGCTTCGGGGCGGATGTGACATGTGGAGAGATGGCCGTCTGCAC
CAACCTGCTGCAGGGCCAGATGTCCGAGTGGGCCCTACTCAAACGCCACCAGTGTGAGGACATC
TTTGGCGTCCAGCTGGAGGGCGCCTTCCCCGACACCATGACCAAGTGTGCCGAGCTGCTGAGCC
GCACCGTGGAGGTGGACTTTGTGGACATCAACGTCGGCTGCCCCATCGACCTCGTGTACAAGAA
GGGTGGGGGCTGTGCCCTCATGAATCGCTCCACCAAGTTCCAGCAGATCGTCCGTGGCATGAAC
CAGGTGCTGGATGTGCCGCTGACTGTGAAGATCCGCACAGGCGTCCAGGAGCGTGTGAACCTGG
CGCACCGCCTGCTGCCCGAGCTGCGGGACTGGGGCGTGGCACTCGTCACGCCTGGCTCTCTTGG
TCTCTTCCTCTCTGCGTCTCACTCTCTGCCTCCTACCCTGCGTGGCGGCTTCTCCCCCAGCTCC
ACGGCCGCTCTCGGGAGCAGCGCTACACCAAGCTAGCCGACTGGCAGTACATCGAGGAGTGCGT
GCAGGCCGCCAGCCCCATGCCCCTGTTCGGAAATGGGGACATCTTGTCATTTGAGGATGCCAAC
CGCGCCATGCAGACTGGTGTCACCGGGATCATGATTGCCCGTGGCGCCCTGCTCAAGCCGTGGC
TCTTCACGGAGATCAAGGAGCAGCGGCACTGGGACATCTCGTCGTCCGAGCGCCTGGACATCCT
GCGGGACTTCACCAACTACGGCCTGGAGCACTGGGGCTCGGACACGCAGGGCGTGGAGAAGACC
CGGCGCTTTCTGCTCGAGTGGCTGTCCTTCCTGTGCCGGTACGTGCCCGTGGGGCTGCTGGAGC
GGCTCCCACAGAGGATCAACGAGCGGCCGCCCTACTACCTGGGCCGCGACTACCTGGAGACGCT
GATGGCCAGCCAGAAGGCAGCCGACTGGATCCGCATCAGCGAGATGCTCCTTGGGCCAGTGCCC
CCCAGCTTCGCCTTCTTGCCGAAGCACAAGGCCAACGCGTACAAGTAGCCTCAGGCTTTCCCAG
GGGCACCCTGGGGCGAGGAGAGTACAATAAATTTTATTCTTTTAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001155091	(Get FASTA)	NCBI Sequence Viewer
	NP_064560	(Get FASTA)	NCBI Sequence Viewer
	XP_016882509	(Get FASTA)	NCBI Sequence Viewer
	XP_047295067	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC72941	(Get FASTA)	NCBI Sequence Viewer
	AAH04549	(Get FASTA)	NCBI Sequence Viewer
	AAH08362	(Get FASTA)	NCBI Sequence Viewer
	AAH09973	(Get FASTA)	NCBI Sequence Viewer
	BAB14740	(Get FASTA)	NCBI Sequence Viewer
	BAG38054	(Get FASTA)	NCBI Sequence Viewer
	BAG59565	(Get FASTA)	NCBI Sequence Viewer
	CAB96955	(Get FASTA)	NCBI Sequence Viewer
	EAW69141	(Get FASTA)	NCBI Sequence Viewer
	EAW69142	(Get FASTA)	NCBI Sequence Viewer
	EAW69143	(Get FASTA)	NCBI Sequence Viewer
	EAW69144	(Get FASTA)	NCBI Sequence Viewer
	EAW69145	(Get FASTA)	NCBI Sequence Viewer
	EAW69146	(Get FASTA)	NCBI Sequence Viewer
	Q96G46	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_064560 ⟸ NM_020175
- Peptide Label:	isoform 1
- UniProtKB:	Q9NPR1 (UniProtKB/Swiss-Prot), Q96G46 (UniProtKB/Swiss-Prot), B2RDV7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEGTAEAPLENGGGGDSGAGALERGVAPIKRQYLTTKEQFHQFLEAKGQEKTCRETEVGDPAG NELAEPEAKRIRLEDGQTADGQTEEAAEPGEQLQTQKRARGQNKGRPHVKPTNYDKNRLCPSLI QESAAKCFFGDRCRFLHDVGRYLETKPADLGPRCVLFETFGRCPYGVTCRFAGAHLRPEGQNLV QEELAARGTQPPSIRNGLDKALQQQLRKREVRFERAEQALRRFSQGPTPAAAVPEGTAAEGAPR QENCGAQQVPAGPGTSTPPSSPVRTCGPLTDEDVVRLRPCEKKRLDIRGKLYLAPLTTCGNLPF RRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIFGVQLEGAFPDTMTKCAELLSRT VEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVRGMNQVLDVPLTVKIRTGVQERVNLAH RLLPELRDWGVALVTLHGRSREQRYTKLADWQYIEECVQAASPMPLFGNGDILSFEDANRAMQT GVTGIMIARGALLKPWLFTEIKEQRHWDISSSERLDILRDFTNYGLEHWGSDTQGVEKTRRFLL EWLSFLCRYVPVGLLERLPQRINERPPYYLGRDYLETLMASQKAADWIRISEMLLGPVPPSFAF LPKHKANAYK hide sequence

RefSeq Acc Id:	NP_001155091 ⟸ NM_001161619
- Peptide Label:	isoform 2
- UniProtKB:	Q96G46 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAEGTAEAPLENGGGGDSGAGALERGVAPIKRQYLTTKEQFHQFLEAKGQEKTCRETELDIRGK LYLAPLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIFGVQLEGAF PDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVRGMNQVLDVPLTV KIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRYTKLADWQYIEECVQAASPMPLFGNG DILSFEDANRAMQTGVTGIMIARGALLKPWLFTEIKEQRHWDISSSERLDILRDFTNYGLEHWG SDTQGVEKTRRFLLEWLSFLCRYVPVGLLERLPQRINERPPYYLGRDYLETLMASQKAADWIRI SEMLLGPVPPSFAFLPKHKANAYK hide sequence

RefSeq Acc Id:

XP_016882509 ⟸ XM_017027020

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAEGTAEAPLENGGGGDSGAGALERGVAPIKRQYLTTKEQFHQFLEAKGQEKTCRETEVGDPAG
NELAEPEAKRIRLEDGQTADGQTEEAAEPGEQLQTQKRARGQNKGRPHVKPTNYDKNRLCPSLI
QESAAKCFFGDRCRFLHDVGRYLETKPADLGPRCVLFETFGRCPYGVTCRFAGAHLRPEGQNLV
QEELAARGTQPPSIRNGLDKALQQQLRKREVRFERAEQALRRFSQGPTPAAAVPEGTAAEGAPR
QENCGAQQVPAGPGTSTPPSSPVRTCGPLTDEDVVRLRPCEKKRCGNLPFRRICKRFGADVTCG
EMAVCTNLLQGQMSEWALLKRHQCEDIFGVQLEGAFPDTMTKCAELLSRTVEVDFVDINVGCPI
DLVYKKGGGCALMNRSTKFQQIVRGMNQVLDVPLTVKIRTGVQERVNLAHRLLPELRDWGVALV
TLHGRSREQRYTKLADWQYIEECVQAASPMPLFGNGDILSFEDANRAMQTGVTGIMIARGALLK
PWLFTEIKEQRHWDISSSERLDILRDFTNYGLEHWGSDTQGVEKTRRFLLEWLSFLCRYVPVGL
LERLPQRINERPPYYLGRDYLETLMASQKAADWIRISEMLLGPVPPSFAFLPKHKANAYK

hide sequence

RefSeq Acc Id:

ENSP00000311977 ⟸ ENST00000309061

RefSeq Acc Id:

ENSP00000315558 ⟸ ENST00000320699

RefSeq Acc Id:

ENSP00000468233 ⟸ ENST00000585587

RefSeq Acc Id:

ENSP00000466351 ⟸ ENST00000590343

RefSeq Acc Id:

ENSP00000465369 ⟸ ENST00000590110

RefSeq Acc Id:

ENSP00000467987 ⟸ ENST00000591560

RefSeq Acc Id:

ENSP00000468075 ⟸ ENST00000592468

RefSeq Acc Id:

ENSP00000467302 ⟸ ENST00000592491

RefSeq Acc Id:	XP_047295067 ⟸ XM_047439111
- Peptide Label:	isoform X2

Protein Domains

C3H1-type DUS-like FMN-binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q96G46-F1-model_v2	AlphaFold	Q96G46	1-650	view protein structure

Promoters

RGD ID:

6795363

Promoter ID:

HG_KWN:28623

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, CD4+TCell_2Hour, HeLa_S3, Jurkat, K562, Lymphoblastoid, NB4

Transcripts:

UC002MDC.1, UC002MDD.1, UC010DUK.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	19	5,741,771 - 5,742,312 (-)	MPROMDB

RGD ID:

7238173

Promoter ID:

EPDNEW_H24832

Type:

initiation region

Name:

DUS3L_1

Description:

dihydrouridine synthase 3 like

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	5,791,163 - 5,791,223	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:26920	AgrOrtholog
COSMIC	DUS3L	COSMIC
Ensembl Genes	ENSG00000141994	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSP00000311977	ENTREZGENE
	ENSP00000311977.5	UniProtKB/Swiss-Prot
	ENSP00000315558	ENTREZGENE
	ENSP00000315558.7	UniProtKB/Swiss-Prot
	ENSP00000465369.1	UniProtKB/TrEMBL
	ENSP00000466351.1	UniProtKB/TrEMBL
	ENSP00000467302.1	UniProtKB/TrEMBL
	ENSP00000467987.1	UniProtKB/TrEMBL
	ENSP00000468075.1	UniProtKB/TrEMBL
	ENSP00000468233.1	UniProtKB/TrEMBL
Ensembl Transcript	ENST00000309061	ENTREZGENE
	ENST00000309061.12	UniProtKB/Swiss-Prot
	ENST00000320699	ENTREZGENE
	ENST00000320699.12	UniProtKB/Swiss-Prot
	ENST00000585587.1	UniProtKB/TrEMBL
	ENST00000590110.2	UniProtKB/TrEMBL
	ENST00000590343.1	UniProtKB/TrEMBL
	ENST00000591560.5	UniProtKB/TrEMBL
	ENST00000592468.5	UniProtKB/TrEMBL
	ENST00000592491.1	UniProtKB/TrEMBL
Gene3D-CATH	3.20.20.70	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Zinc finger, CCCH-type	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000141994	GTEx
HGNC ID	HGNC:26920	ENTREZGENE
Human Proteome Map	DUS3L	Human Proteome Map
InterPro	Aldolase_TIM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	DUS-like_FMN-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	tRNA_hU_synthase_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf-CCCH_4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_CCCH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:56931	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	56931	ENTREZGENE
PANTHER	TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE	UniProtKB/Swiss-Prot
	TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE	UniProtKB/Swiss-Prot
	TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE	UniProtKB/TrEMBL
	TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE	UniProtKB/TrEMBL
Pfam	Dus	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	zf-CCCH_4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA142671938	PharmGKB
PROSITE	UPF0034	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_C3H1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	FMN-linked oxidoreductases	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	B2RDV7	ENTREZGENE, UniProtKB/TrEMBL
	D6W636_HUMAN	UniProtKB/TrEMBL
	DUS3L_HUMAN	UniProtKB/Swiss-Prot
	K7EJX8_HUMAN	UniProtKB/TrEMBL
	K7EM42_HUMAN	UniProtKB/TrEMBL
	K7EPA4_HUMAN	UniProtKB/TrEMBL
	K7EQU9_HUMAN	UniProtKB/TrEMBL
	K7ER20_HUMAN	UniProtKB/TrEMBL
	K7ERF2_HUMAN	UniProtKB/TrEMBL
	Q96G46	ENTREZGENE
	Q9NPR1	ENTREZGENE
UniProt Secondary	Q96HM5	UniProtKB/Swiss-Prot
	Q9BSU4	UniProtKB/Swiss-Prot
	Q9H877	UniProtKB/Swiss-Prot
	Q9NPR1	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-18	DUS3L	dihydrouridine synthase 3 like		dihydrouridine synthase 3-like	Symbol and/or name change	5135510	APPROVED
2015-07-07	DUS3L	dihydrouridine synthase 3-like		dihydrouridine synthase 3-like (S. cerevisiae)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar