ADPRM (ADP-ribose/CDP-alcohol diphosphatase, manganese dependent) - Rat Genome Database

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Gene: ADPRM (ADP-ribose/CDP-alcohol diphosphatase, manganese dependent) Homo sapiens
Analyze
Symbol: ADPRM
Name: ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
RGD ID: 1604325
HGNC Page HGNC:30925
Description: Predicted to enable 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity; manganese ion binding activity; and pyrophosphatase activity. Predicted to be located in cytosol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent; ADP-ribose/CDP-alcohol pyrophosphatase; ADPRibase-Mn; C17orf48; CDP-choline phosphohydrolase; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase; MDS006; NBLA03831
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381710,697,594 - 10,711,558 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1710,697,594 - 10,711,558 (+)EnsemblGRCh38hg38GRCh38
GRCh371710,600,911 - 10,614,875 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361710,541,652 - 10,555,600 (+)NCBINCBI36Build 36hg18NCBI36
Celera1710,631,781 - 10,645,729 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef1710,500,972 - 10,514,921 (+)NCBIHuRef
CHM1_11710,611,136 - 10,625,085 (+)NCBICHM1_1
T2T-CHM13v2.01710,605,146 - 10,619,111 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (TAS)
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16344560   PMID:18352857   PMID:19460752   PMID:21873635   PMID:25692488   PMID:30033366  


Genomics

Comparative Map Data
ADPRM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381710,697,594 - 10,711,558 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1710,697,594 - 10,711,558 (+)EnsemblGRCh38hg38GRCh38
GRCh371710,600,911 - 10,614,875 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361710,541,652 - 10,555,600 (+)NCBINCBI36Build 36hg18NCBI36
Celera1710,631,781 - 10,645,729 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef1710,500,972 - 10,514,921 (+)NCBIHuRef
CHM1_11710,611,136 - 10,625,085 (+)NCBICHM1_1
T2T-CHM13v2.01710,605,146 - 10,619,111 (+)NCBIT2T-CHM13v2.0
Adprm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391166,928,706 - 66,943,481 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1166,928,731 - 66,943,420 (-)EnsemblGRCm39 Ensembl
GRCm381167,037,880 - 67,052,631 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,037,905 - 67,052,594 (-)EnsemblGRCm38mm10GRCm38
MGSCv371166,851,382 - 66,866,120 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361166,854,100 - 66,868,789 (-)NCBIMGSCv36mm8
Celera1173,977,216 - 73,991,970 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.59NCBI
Adprm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81052,231,085 - 52,243,637 (-)NCBIGRCr8
mRatBN7.21051,732,073 - 51,744,635 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1051,731,993 - 51,744,635 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1056,388,140 - 56,400,623 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01055,878,112 - 55,890,583 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01051,388,498 - 51,400,954 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01053,583,275 - 53,595,821 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1053,583,276 - 53,595,827 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01053,334,308 - 53,346,857 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41053,738,762 - 53,751,242 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11053,752,385 - 53,764,865 (-)NCBI
Celera1050,915,191 - 50,927,669 (-)NCBICelera
Cytogenetic Map10q24NCBI
Adprm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554676,506,059 - 6,511,308 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554676,505,957 - 6,519,823 (-)NCBIChiLan1.0ChiLan1.0
ADPRM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21963,039,859 - 63,053,403 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11767,849,369 - 67,862,922 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01740,942,944 - 40,956,494 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11745,690,100 - 45,703,632 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1745,690,100 - 45,703,632 (-)Ensemblpanpan1.1panPan2
ADPRM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1534,971,737 - 34,982,581 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl534,971,660 - 34,982,134 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha535,108,381 - 35,122,471 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0535,076,818 - 35,090,932 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl535,076,757 - 35,087,280 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1535,042,279 - 35,056,393 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0534,999,403 - 35,013,300 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0535,180,807 - 35,194,664 (+)NCBIUU_Cfam_GSD_1.0
Adprm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560250,063,748 - 50,075,044 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365953,537,893 - 3,549,879 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365953,537,988 - 3,550,565 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADPRM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1255,423,889 - 55,442,676 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11255,423,092 - 55,524,140 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21258,056,080 - 58,078,323 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADPRM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11610,036,943 - 10,050,420 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1610,044,098 - 10,052,261 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605911,293,999 - 11,307,472 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adprm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478613,053,303 - 13,068,228 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478613,053,214 - 13,068,110 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ADPRM
14 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17p13.2-12(chr17:5732953-12095349)x3 copy number gain See cases [RCV000134851] Chr17:5732953..12095349 [GRCh38]
Chr17:5636273..11998666 [GRCh37]
Chr17:5576997..11939391 [NCBI36]
Chr17:17p13.2-12		 pathogenic
GRCh38/hg38 17p13.3-12(chr17:162016-12343901)x3 copy number gain See cases [RCV000138531] Chr17:162016..12343901 [GRCh38]
Chr17:45835..12247218 [GRCh37]
Chr17:11807..12187943 [NCBI36]
Chr17:17p13.3-12		 pathogenic
GRCh38/hg38 17p13.1-12(chr17:10334509-10900316)x1 copy number loss See cases [RCV000139368] Chr17:10334509..10900316 [GRCh38]
Chr17:10237826..10803633 [GRCh37]
Chr17:10178551..10744358 [NCBI36]
Chr17:17p13.1-12		 pathogenic
GRCh38/hg38 17p13.3-12(chr17:150732-14764202)x3 copy number gain See cases [RCV000142236] Chr17:150732..14764202 [GRCh38]
Chr17:525..14667519 [GRCh37]
Chr17:525..14608244 [NCBI36]
Chr17:17p13.3-12		 pathogenic
GRCh38/hg38 17p13.1-12(chr17:9701182-11983353)x1 copy number loss Breast ductal adenocarcinoma [RCV000207166] Chr17:9701182..11983353 [GRCh38]
Chr17:9604499..11886670 [GRCh37]
Chr17:17p13.1-12		 uncertain significance
Single allele complex Breast ductal adenocarcinoma [RCV000207129] Chr17:9586165..16325968 [GRCh37]
Chr17:17p13.1-11.2		 uncertain significance
GRCh37/hg19 17p13.1(chr17:10583805-10633471)x1 copy number loss See cases [RCV000448993] Chr17:10583805..10633471 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-12(chr17:525-15027737)x3 copy number gain See cases [RCV000511786] Chr17:525..15027737 [GRCh37]
Chr17:17p13.3-12		 pathogenic
NM_020233.5(ADPRM):c.802C>G (p.His268Asp) single nucleotide variant Inborn genetic diseases [RCV003266399] Chr17:10710917 [GRCh38]
Chr17:10614234 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-12(chr17:525-11186432)x3 copy number gain not provided [RCV000683866] Chr17:525..11186432 [GRCh37]
Chr17:17p13.3-12		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
NM_020233.5(ADPRM):c.-18+76G>C single nucleotide variant not provided [RCV001678753] Chr17:10697743 [GRCh38]
Chr17:10601060 [GRCh37]
Chr17:17p13.1		 benign
GRCh37/hg19 17p13.1(chr17:10583589-10698588)x3 copy number gain not provided [RCV000751926] Chr17:10583589..10698588 [GRCh37]
Chr17:17p13.1		 benign
GRCh37/hg19 17p13.1-12(chr17:10604119-10744366)x1 copy number loss not provided [RCV000849322] Chr17:10604119..10744366 [GRCh37]
Chr17:17p13.1-12		 uncertain significance
NM_020233.5(ADPRM):c.974G>A (p.Gly325Asp) single nucleotide variant Inborn genetic diseases [RCV003250163] Chr17:10711089 [GRCh38]
Chr17:10614406 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_020233.5(ADPRM):c.-87G>A single nucleotide variant not provided [RCV001636014] Chr17:10697598 [GRCh38]
Chr17:10600915 [GRCh37]
Chr17:17p13.1		 benign
NM_020233.5(ADPRM):c.-18+136C>T single nucleotide variant not provided [RCV001596427] Chr17:10697803 [GRCh38]
Chr17:10601120 [GRCh37]
Chr17:17p13.1		 likely benign
NM_020233.5(ADPRM):c.-18+149_-18+150insG insertion not provided [RCV001673494] Chr17:10697816..10697817 [GRCh38]
Chr17:10601133..10601134 [GRCh37]
Chr17:17p13.1		 benign
GRCh37/hg19 17p13.1-12(chr17:10493837-15099023)x1 copy number loss See cases [RCV001195076] Chr17:10493837..15099023 [GRCh37]
Chr17:17p13.1-12		 uncertain significance
NM_020233.5(ADPRM):c.-31G>A single nucleotide variant not provided [RCV001640843] Chr17:10697654 [GRCh38]
Chr17:10600971 [GRCh37]
Chr17:17p13.1		 benign
NM_020233.5(ADPRM):c.-18+52T>G single nucleotide variant not provided [RCV001589693] Chr17:10697719 [GRCh38]
Chr17:10601036 [GRCh37]
Chr17:17p13.1		 likely benign
GRCh37/hg19 17p13.1-12(chr17:10517286-10814075)x3 copy number gain not provided [RCV002472694] Chr17:10517286..10814075 [GRCh37]
Chr17:17p13.1-12		 uncertain significance
NM_020233.5(ADPRM):c.971G>A (p.Arg324Lys) single nucleotide variant Inborn genetic diseases [RCV002990250] Chr17:10711086 [GRCh38]
Chr17:10614403 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_020233.5(ADPRM):c.256T>C (p.Ser86Pro) single nucleotide variant Inborn genetic diseases [RCV002799464] Chr17:10705182 [GRCh38]
Chr17:10608499 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_020233.5(ADPRM):c.742G>A (p.Ala248Thr) single nucleotide variant Inborn genetic diseases [RCV003000736] Chr17:10710857 [GRCh38]
Chr17:10614174 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_020233.5(ADPRM):c.46C>T (p.Arg16Cys) single nucleotide variant Inborn genetic diseases [RCV003173483] Chr17:10704972 [GRCh38]
Chr17:10608289 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_020233.5(ADPRM):c.13C>T (p.Pro5Ser) single nucleotide variant Inborn genetic diseases [RCV003265037] Chr17:10704939 [GRCh38]
Chr17:10608256 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh38/hg38 17p13.3-12(chr17:165730-11404096)x3 copy number gain Chromosome 17p13.3 duplication syndrome [RCV003327726] Chr17:165730..11404096 [GRCh38]
Chr17:17p13.3-12		 pathogenic
NM_020233.5(ADPRM):c.217G>A (p.Gly73Arg) single nucleotide variant Inborn genetic diseases [RCV003359929] Chr17:10705143 [GRCh38]
Chr17:10608460 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.3-11.2(chr17:525-21510992)x3 copy number gain not specified [RCV003987215] Chr17:525..21510992 [GRCh37]
Chr17:17p13.3-11.2		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:510
Count of miRNA genes:348
Interacting mature miRNAs:366
Transcripts:ENST00000379774, ENST00000468843, ENST00000527582, ENST00000609540
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH98491  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371710,608,285 - 10,608,441UniSTSGRCh37
Build 361710,549,010 - 10,549,166RGDNCBI36
Celera1710,639,139 - 10,639,295RGD
Cytogenetic Map17p13.1UniSTS
HuRef1710,508,331 - 10,508,487UniSTS
GeneMap99-GB4 RH Map1769.43UniSTS
RH94236  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371710,614,154 - 10,614,287UniSTSGRCh37
Build 361710,554,879 - 10,555,012RGDNCBI36
Celera1710,645,008 - 10,645,141RGD
Cytogenetic Map17p13.1UniSTS
HuRef1710,514,200 - 10,514,333UniSTS
GeneMap99-GB4 RH Map1769.43UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1764 1461 1004 194 1176 95 3520 1062 967 184 1281 1291 109 1 1015 2227 2
Low 675 1528 722 430 774 370 837 1134 2767 235 179 322 65 189 561 4 2
Below cutoff 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000379774   ⟹   ENSP00000369099
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1710,697,594 - 10,711,558 (+)Ensembl
RefSeq Acc Id: ENST00000468843   ⟹   ENSP00000431622
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1710,697,614 - 10,711,233 (+)Ensembl
RefSeq Acc Id: ENST00000527582
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1710,697,616 - 10,705,928 (+)Ensembl
RefSeq Acc Id: ENST00000609540   ⟹   ENSP00000477021
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1710,704,900 - 10,711,230 (+)Ensembl
RefSeq Acc Id: NM_020233   ⟹   NP_064618
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381710,697,594 - 10,711,558 (+)NCBI
GRCh371710,600,927 - 10,616,264 (+)NCBI
Build 361710,541,652 - 10,555,600 (+)NCBI Archive
Celera1710,631,781 - 10,645,729 (+)RGD
HuRef1710,500,972 - 10,514,921 (+)RGD
CHM1_11710,611,136 - 10,625,085 (+)NCBI
T2T-CHM13v2.01710,605,146 - 10,619,111 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_064618   ⟸   NM_020233
- UniProtKB: Q9BVD4 (UniProtKB/Swiss-Prot),   D3DTS4 (UniProtKB/Swiss-Prot),   A8K9B4 (UniProtKB/Swiss-Prot),   Q9NRU8 (UniProtKB/Swiss-Prot),   Q3LIE5 (UniProtKB/Swiss-Prot),   W0NWJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000477021   ⟸   ENST00000609540
RefSeq Acc Id: ENSP00000431622   ⟸   ENST00000468843
RefSeq Acc Id: ENSP00000369099   ⟸   ENST00000379774
Protein Domains
Calcineurin-like phosphoesterase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3LIE5-F1-model_v2 AlphaFold Q3LIE5 1-342 view protein structure

Promoters
RGD ID:6794546
Promoter ID:HG_KWN:25012
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_004589,   NM_020233,   UC002GMS.2,   UC002GMU.1,   UC002GMV.1,   UC010COK.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361710,541,349 - 10,541,849 (-)MPROMDB
RGD ID:7234009
Promoter ID:EPDNEW_H22751
Type:single initiation site
Name:ADPRM_2
Description:ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22753  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381710,696,754 - 10,696,814EPDNEW
RGD ID:7234015
Promoter ID:EPDNEW_H22753
Type:initiation region
Name:ADPRM_1
Description:ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22751  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381710,697,643 - 10,697,703EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:30925 AgrOrtholog
COSMIC ADPRM COSMIC
Ensembl Genes ENSG00000170222 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000379774 ENTREZGENE
  ENST00000379774.5 UniProtKB/Swiss-Prot
  ENST00000468843.1 UniProtKB/Swiss-Prot
  ENST00000609540.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.21.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000170222 GTEx
HGNC ID HGNC:30925 ENTREZGENE
Human Proteome Map ADPRM Human Proteome Map
InterPro Calcineurin-like_PHP_ApaH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Metallo-depent_PP-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MPP_ADPRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:56985 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 56985 ENTREZGENE
PANTHER MANGANESE-DEPENDENT ADP-RIBOSE/CDP-ALCOHOL DIPHOSPHATASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16509 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Metallophos UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA142672231 PharmGKB
Superfamily-SCOP SSF56300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8K9B4 ENTREZGENE
  ADPRM_HUMAN UniProtKB/Swiss-Prot
  D3DTS4 ENTREZGENE
  Q3LIE5 ENTREZGENE
  Q9BVD4 ENTREZGENE
  Q9NRU8 ENTREZGENE
  V9GYR6_HUMAN UniProtKB/TrEMBL
  W0NWJ0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A8K9B4 UniProtKB/Swiss-Prot
  D3DTS4 UniProtKB/Swiss-Prot
  Q9BVD4 UniProtKB/Swiss-Prot
  Q9NRU8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-28 ADPRM  ADP-ribose/CDP-alcohol diphosphatase, manganese dependent    ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent  Symbol and/or name change 5135510 APPROVED
2012-07-24 ADPRM  ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent  C17orf48  chromosome 17 open reading frame 48  Symbol and/or name change 5135510 APPROVED