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Gene: NUAK2 (NUAK family kinase 2) Homo sapiens
Symbol: NUAK2
Name: NUAK family kinase 2
Description: Exhibits ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in several processes, including actin cytoskeleton organization; cellular response to glucose starvation; and negative regulation of apoptotic process. Predicted to localize to the cytoplasm and nucleus; INTERACTS WITH aflatoxin B1; antirheumatic drug; arsane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp434J037; DKFZp686F01113; FLJ90349; NUAK family SNF1-like kinase 2; NUAK family, SNF1-like kinase, 2; omphalocele kinase 2; SNARK; SNF1/AMP activated protein kinase; SNF1/AMP kinase-related kinase
Mus musculus (house mouse) : Nuak2 (NUAK family, SNF1-like kinase, 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nuak2 (NUAK family kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nuak2 (NUAK family kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NUAK2 (NUAK family kinase 2)
Canis lupus familiaris (dog) : NUAK2 (NUAK family kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nuak2 (NUAK family kinase 2)
Sus scrofa (pig) : NUAK2 (NUAK family kinase 2)
Chlorocebus sabaeus (green monkey) : NUAK2 (NUAK family kinase 2)
Heterocephalus glaber (naked mole-rat) : Nuak2 (NUAK family kinase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1205,302,063 - 205,321,760 (-)Ensembl
GRCh381205,302,059 - 205,321,745 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371205,271,191 - 205,290,883 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361203,537,814 - 203,557,506 (-)NCBINCBI36hg18NCBI36
Celera1178,406,280 - 178,425,974 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1176,436,830 - 176,456,534 (-)NCBIHuRef
CHM1_11206,694,514 - 206,714,241 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NUAK2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603952
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.