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Gene: LARP1 (La ribonucleoprotein 1, translational regulator) Homo sapiens
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Symbol: LARP1
Name: La ribonucleoprotein 1, translational regulator
Description: Exhibits eukaryotic initiation factor 4E binding activity; nucleic acid binding activity; and ribosomal small subunit binding activity. Involved in several processes, including TORC1 signaling; cellular response to rapamycin; and posttranscriptional regulation of gene expression. Localizes to the cytoplasmic stress granule. Colocalizes with the TORC1 complex and polysomal ribosome; INTERACTS WITH 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA0731; La ribonucleoprotein domain family member 1; La ribonucleoprotein domain family, member 1; la-related protein 1; LARP; MGC19556
Orthologs:
Mus musculus (house mouse) : Larp1 (La ribonucleoprotein domain family, member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Larp1 (La ribonucleoprotein 1, translational regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Larp1 (La ribonucleoprotein 1, translational regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : LARP1 (La ribonucleoprotein 1, translational regulator)
Canis lupus familiaris (dog) : LARP1 (La ribonucleoprotein 1, translational regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Larp1 (La ribonucleoprotein 1, translational regulator)
Sus scrofa (pig) : LARP1 (La ribonucleoprotein 1, translational regulator)
more info ...
Related Pseudogenes: LARP1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385154,682,979 - 154,817,605 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375154,062,224 - 154,197,167 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365154,072,655 - 154,177,358 (+)NCBINCBI36hg18NCBI36
Celera5150,169,448 - 150,274,651 (+)NCBI
Cytogenetic Map5q33.2NCBI
HuRef5149,234,294 - 149,339,464 (+)NCBIHuRef
CHM1_15153,524,904 - 153,629,585 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LARP1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603686
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.