Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: LARP1 (La ribonucleoprotein 1, translational regulator) Homo sapiens
Symbol: LARP1
Name: La ribonucleoprotein 1, translational regulator
Description: Exhibits eukaryotic initiation factor 4E binding activity; nucleic acid binding activity; and ribosomal small subunit binding activity. Involved in several processes, including TORC1 signaling; cellular response to rapamycin; and posttranscriptional regulation of gene expression. Localizes to the cytoplasmic stress granule. Colocalizes with the TORC1 complex and polysomal ribosome; INTERACTS WITH 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA0731; La ribonucleoprotein domain family member 1; La ribonucleoprotein domain family, member 1; la-related protein 1; LARP; MGC19556
Mus musculus (house mouse) : Larp1 (La ribonucleoprotein domain family, member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Larp1 (La ribonucleoprotein 1, translational regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Larp1 (La ribonucleoprotein 1, translational regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : LARP1 (La ribonucleoprotein 1, translational regulator)
Canis lupus familiaris (dog) : LARP1 (La ribonucleoprotein 1, translational regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Larp1 (La ribonucleoprotein 1, translational regulator)
Sus scrofa (pig) : LARP1 (La ribonucleoprotein 1, translational regulator)
more info ...
Related Pseudogenes: LARP1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh385154,682,979 - 154,817,605 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375154,062,224 - 154,197,167 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365154,072,655 - 154,177,358 (+)NCBINCBI36hg18NCBI36
Celera5150,169,448 - 150,274,651 (+)NCBI
Cytogenetic Map5q33.2NCBI
HuRef5149,234,294 - 149,339,464 (+)NCBIHuRef
CHM1_15153,524,904 - 153,629,585 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LARP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603686
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.