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Gene: UNC45A (unc-45 myosin chaperone A) Homo sapiens
Symbol: UNC45A
Name: unc-45 myosin chaperone A
Description: This gene encodes a regulatory component of the progesterone receptor/heat shock protein 90 chaperoning complex, which functions in the assembly and folding of the progesterone receptor. The encoded protein is thought to be essential for normal cell proliferation, and for the accumulation of myosin during development of muscle cells. [provided by RefSeq, Sep 2018]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ10043; GC-UNC45; GCUNC-45; GCUNC45; general cell UNC45; IRO039700; SMAP-1; SMAP1; smooth muscle cell associated protein-1; smooth muscle cell-associated protein 1; unc-45 homolog A; UNC-45A
Mus musculus (house mouse) : Unc45a (unc-45 myosin chaperone A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Unc45a (unc-45 myosin chaperone A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Unc45a (unc-45 myosin chaperone A)
Pan paniscus (bonobo/pygmy chimpanzee) : UNC45A (unc-45 myosin chaperone A)
Canis lupus familiaris (dog) : UNC45A (unc-45 myosin chaperone A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Unc45a (unc-45 myosin chaperone A)
Sus scrofa (pig) : UNC45A (unc-45 myosin chaperone A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381590,930,180 - 90,954,093 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371591,473,410 - 91,497,323 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361589,274,414 - 89,298,327 (+)NCBINCBI36hg18NCBI36
Celera1567,882,608 - 67,906,541 (+)NCBI
Cytogenetic Map15q26.1NCBI
HuRef1567,584,693 - 67,608,337 (+)NCBIHuRef
CHM1_11591,315,008 - 91,338,915 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on UNC45A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603630
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.