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Gene: ICMT (isoprenylcysteine carboxyl methyltransferase) Homo sapiens
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Symbol: ICMT
Name: isoprenylcysteine carboxyl methyltransferase
Description: Predicted to have protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity. Predicted to be involved in C-terminal protein methylation. Localizes to endoplasmic reticulum.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HSTE14; MGC39955; MST098; MSTP098; PCCMT; PCMT; PPMT; prenylated protein carboxyl methyltransferase; prenylcysteine carboxyl methyltransferase; protein-S isoprenylcysteine O-methyltransferase; protein-S-isoprenylcysteine O-methyltransferase
Orthologs:
Mus musculus (house mouse) : Icmt (isoprenylcysteine carboxyl methyltransferase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Icmt (isoprenylcysteine carboxyl methyltransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Icmt (isoprenylcysteine carboxyl methyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : ICMT (isoprenylcysteine carboxyl methyltransferase)
Canis lupus familiaris (dog) : ICMT (isoprenylcysteine carboxyl methyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Icmt (isoprenylcysteine carboxyl methyltransferase)
Sus scrofa (pig) : ICMT (isoprenylcysteine carboxyl methyltransferase)
Chlorocebus sabaeus (African green monkey) : ICMT (isoprenylcysteine carboxyl methyltransferase)
Heterocephalus glaber (naked mole-rat) : Icmt (isoprenylcysteine carboxyl methyltransferase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl16,221,193 - 6,235,972 (-)EnsemblGRCh38hg38GRCh38
GRCh3816,221,193 - 6,235,964 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3716,281,253 - 6,296,044 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3616,203,840 - 6,218,631 (-)NCBINCBI36hg18NCBI36
Celera15,395,764 - 5,410,546 (-)NCBI
Cytogenetic Map1p36.31NCBI
HuRef15,429,524 - 5,444,303 (-)NCBIHuRef
CHM1_116,269,895 - 6,284,684 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ICMT
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603405
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.