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Gene: PPP4R3B (protein phosphatase 4 regulatory subunit 3B) Homo sapiens
Symbol: PPP4R3B
Name: protein phosphatase 4 regulatory subunit 3B
Description: Predicted to be involved in positive regulation of gluconeogenesis; protein dephosphorylation; and regulation of lipid metabolic process. Localizes to centrosome and nuclear speck; INTERACTS WITH (-)-demecolcine; 2,3,7,8-tetrachlorodibenzodioxine; 2-hydroxypropanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLFL2; FLJ31474; KIAA1387; PP4R3B; PSY2; serine/threonine-protein phosphatase 4 regulatory subunit 3B; SMEK homolog 2, suppressor of mek1; SMEK2; smk1
Mus musculus (house mouse) : Ppp4r3b (protein phosphatase 4 regulatory subunit 3B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ppp4r3b (protein phosphatase 4, regulatory subunit 3B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppp4r3b (protein phosphatase 4 regulatory subunit 3B)
Pan paniscus (bonobo/pygmy chimpanzee) : PPP4R3B (protein phosphatase 4 regulatory subunit 3B)
Canis lupus familiaris (dog) : PPP4R3B (protein phosphatase 4 regulatory subunit 3B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppp4r3b (protein phosphatase 4 regulatory subunit 3B)
Sus scrofa (pig) : PPP4R3B (protein phosphatase 4 regulatory subunit 3B)
Chlorocebus sabaeus (African green monkey) : PPP4R3B (protein phosphatase 4 regulatory subunit 3B)
Heterocephalus glaber (naked mole-rat) : Ppp4r3b (protein phosphatase 4 regulatory subunit 3B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl255,547,292 - 55,618,880 (-)EnsemblGRCh38hg38GRCh38
GRCh38255,547,292 - 55,618,132 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37255,774,428 - 55,844,860 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36255,629,018 - 55,698,253 (-)NCBINCBI36hg18NCBI36
Celera255,615,913 - 55,685,202 (-)NCBI
Cytogenetic Map2p16.1NCBI
HuRef255,510,771 - 55,579,889 (-)NCBIHuRef
CHM1_1255,705,046 - 55,775,412 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PPP4R3B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603387
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.