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Gene: SDE2 (SDE2 telomere maintenance homolog) Homo sapiens
Symbol: SDE2
Name: SDE2 telomere maintenance homolog
RGD ID: 1603354
Description: Exhibits damaged DNA binding activity. Involved in several processes, including cellular response to UV; protein ubiquitination; and regulation of cell cycle arrest. Localizes to several cellular components, including Golgi apparatus; cytosol; and nuclear speck; INTERACTS WITH 2-hydroxypropanoic acid; aflatoxin B1; arsane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C1orf55; dJ671D7.1; FLJ35382; hypothetical protein LOC163859; protein SDE2 homolog; replication stress response regulator SDE2; RP4-671D7.1; SDE2 telomere maintenance homolog (S. pombe); UPF0667 protein C1orf55
Mus musculus (house mouse) : Sde2 (SDE2 telomere maintenance homolog (S. pombe))  MGI  Alliance
Rattus norvegicus (Norway rat) : Sde2 (SDE2 telomere maintenance homolog)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sde2 (SDE2 telomere maintenance homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : SDE2 (SDE2 telomere maintenance homolog)
Canis lupus familiaris (dog) : SDE2 (SDE2 telomere maintenance homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sde2 (SDE2 telomere maintenance homolog)
Sus scrofa (pig) : SDE2 (SDE2 telomere maintenance homolog)
Chlorocebus sabaeus (African green monkey) : SDE2 (SDE2 telomere maintenance homolog)
Heterocephalus glaber (naked mole-rat) : Sde2 (SDE2 telomere maintenance homolog)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1225,982,702 - 225,999,343 (-)EnsemblGRCh38hg38GRCh38
GRCh381225,982,702 - 225,999,343 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371226,170,403 - 226,187,099 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361224,237,026 - 224,253,689 (-)NCBINCBI36hg18NCBI36
Celera1199,361,495 - 199,378,155 (-)NCBI
Cytogenetic Map1q42.12NCBI
HuRef1196,688,260 - 196,704,921 (-)NCBIHuRef
CHM1_11227,443,144 - 227,459,807 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SDE2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603354
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.