Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MRGPRX2 (MAS related GPR family member X2) Homo sapiens
Symbol: MRGPRX2
Name: MAS related GPR family member X2
Description: Exhibits G protein-coupled receptor activity and neuropeptide binding activity. Involved in mast cell degranulation and positive regulation of cytokinesis. Predicted to localize to integral component of membrane; INTERACTS WITH (+)-catechin; colistin; doxorubicin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G protein-coupled receptor MRGX2; Mas-related G protein-coupled receptor G3; mas-related G-protein coupled receptor member X2; MAS-related GPR, member X2; MGRG3; MRGX2
Mus musculus (house mouse) : Mrgprx2 (MAS-related GPR, member X2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mrgprx2 (MAS related GPR family member X2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MRGPRX2 (MAS related GPR family member X2)
Canis lupus familiaris (dog) : MRGPRX2 (MAS related GPR family member X2)
Sus scrofa (pig) : MRGPRX2 (MAS related GPR family member X2)
Chlorocebus sabaeus (African green monkey) : MRGPRX2 (MAS related GPR family member X2)
more info ...
Related Pseudogenes: MRGPRX12P   MRGPRX8P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1119,054,455 - 19,060,717 (-)EnsemblGRCh38hg38GRCh38
GRCh381119,054,455 - 19,060,717 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371119,076,002 - 19,082,228 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361119,032,578 - 19,038,804 (-)NCBINCBI36hg18NCBI36
Celera1119,208,469 - 19,214,692 (-)NCBI
Cytogenetic Map11p15.1NCBI
HuRef1118,759,875 - 18,766,099 (-)NCBIHuRef
CHM1_11119,075,324 - 19,081,548 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MRGPRX2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603280
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.