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Gene: MRGPRX4 (MAS related GPR family member X4) Homo sapiens
Symbol: MRGPRX4
Name: MAS related GPR family member X4
Description: Predicted to have G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; chemosensory behavior; and hematopoietic progenitor cell differentiation. Predicted to localize to integral component of membrane and plasma membrane; INTERACTS WITH leflunomide; bisphenol A (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G protein-coupled receptor MRGX4; G protein-coupled receptor SNSR5; G protein-coupled receptor SNSR6; GPCR; Mas-related G protein-coupled receptor X4; mas-related G-protein coupled receptor member X4; MAS-related GPR, member X4; MGC129753; MGC129754; MRGX4; sensory neuron-specific G-protein coupled receptor 5/6; SNSR6
Mus musculus (house mouse) : Mrgprx1 (MAS-related GPR, member X1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mrgprx4 (MAS related GPR family member X4)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MRGPRX4 (MAS related GPR family member X4)
Canis lupus familiaris (dog) : MGRH (mas-related G-protein coupled receptor member X2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1118,172,837 - 18,174,280 (+)EnsemblGRCh38hg38GRCh38
GRCh381118,172,837 - 18,174,280 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371118,194,384 - 18,195,827 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361118,150,960 - 18,152,401 (+)NCBINCBI36hg18NCBI36
Celera1118,326,688 - 18,328,131 (+)NCBI
Cytogenetic Map11p15.1NCBI
HuRef1117,877,287 - 17,878,730 (+)NCBIHuRef
CHM1_11118,193,904 - 18,195,347 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MRGPRX4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603278
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.