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Gene: MIR548D1 (microRNA 548d-1) Homo sapiens
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Symbol: MIR548D1
Name: microRNA 548d-1
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: MIRN548D1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl8123,348,034 - 123,348,130 (-)Ensembl
GRCh388123,348,034 - 123,348,130 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378124,360,274 - 124,360,370 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368124,429,454 - 124,429,550 (-)NCBINCBI36hg18NCBI36
Celera8120,548,926 - 120,549,022 (-)NCBI
Cytogenetic Map8q24.13NCBI
HuRef8119,686,026 - 119,686,122 (-)NCBIHuRef
CHM1_18124,400,708 - 124,400,804 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
References - curated
References - uncurated

Genomics


Expression


Sequence

Nucleotide Sequences
Clinical Variants

Additional Information

External Database Links
 
More on MIR548D1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603126
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.