MIR584 (microRNA 584) - Rat Genome Database

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Gene: MIR584 (microRNA 584) Homo sapiens
Analyze
Symbol: MIR584
Name: microRNA 584
RGD ID: 1603091
HGNC Page HGNC:32840
Description: Predicted to be involved in miRNA-mediated post-transcriptional gene silencing. Located in extracellular space.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: hsa-mir-584; MIRN584
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385149,062,313 - 149,062,409 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5149,062,313 - 149,062,409 (-)EnsemblGRCh38hg38GRCh38
GRCh375148,441,876 - 148,441,972 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365148,422,068 - 148,422,164 (-)NCBINCBI36Build 36hg18NCBI36
Celera5144,523,931 - 144,524,027 (-)NCBICelera
Cytogenetic Map5q32NCBI
HuRef5143,587,150 - 143,587,246 (-)NCBIHuRef
CHM1_15147,874,371 - 147,874,467 (-)NCBICHM1_1
T2T-CHM13v2.05149,597,158 - 149,597,254 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:16505370   PMID:17604727   PMID:17616659   PMID:19665576   PMID:21119662   PMID:22536353   PMID:23479725   PMID:23943853   PMID:25336585   PMID:25674221   PMID:26133786  
PMID:26405762   PMID:26494299   PMID:26646931   PMID:26715733   PMID:27424220   PMID:27661106   PMID:27881000   PMID:28431583   PMID:28609011   PMID:28827574   PMID:30382096   PMID:30429198  
PMID:30431107   PMID:30616889   PMID:30628644   PMID:31044566   PMID:31257521   PMID:31863331   PMID:32096176   PMID:32208890   PMID:32373978   PMID:32420810   PMID:32522621   PMID:32615958  
PMID:33135290   PMID:35451652   PMID:35695194   PMID:36227666   PMID:36382967   PMID:37579846   PMID:38093594  


Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 5q23.3-33.2(chr5:129847794-153353546)x3 copy number gain See cases [RCV000138808] Chr5:129847794..153353546 [GRCh38]
Chr5:129183487..152733106 [GRCh37]
Chr5:129211386..152713299 [NCBI36]
Chr5:5q23.3-33.2		 pathogenic
GRCh38/hg38 5q31.3-32(chr5:141089988-149530678)x3 copy number gain See cases [RCV000139504] Chr5:141089988..149530678 [GRCh38]
Chr5:140469572..148910241 [GRCh37]
Chr5:140449756..148890434 [NCBI36]
Chr5:5q31.3-32		 pathogenic
GRCh38/hg38 5q23.3-33.2(chr5:130860928-155321811)x3 copy number gain See cases [RCV000051193] Chr5:130860928..155321811 [GRCh38]
Chr5:130196621..154701371 [GRCh37]
Chr5:130224520..154681564 [NCBI36]
Chr5:5q23.3-33.2		 pathogenic
GRCh38/hg38 5q21.3-33.2(chr5:106619588-156124387)x1 copy number loss See cases [RCV000053524] Chr5:106619588..156124387 [GRCh38]
Chr5:105955289..155551397 [GRCh37]
Chr5:105983188..155483975 [NCBI36]
Chr5:5q21.3-33.2		 pathogenic
miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
ROCK1hsa-miR-584-5pMirtarbaseexternal_infoImmunohistochemistry//Luciferase reporter assay//MFunctional MTI21119662
ROCK1hsa-miR-584-5pOncomiRDBexternal_infoNANA21119662

Predicted Targets
Summary Value
Count of predictions:30941
Count of gene targets:11668
Count of transcripts:23380
Interacting mature miRNAs:hsa-miR-584-3p, hsa-miR-584-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 1
Low 33 4 11 3 12 3 39 7 10 9 19 28 3 3 10
Below cutoff 34 22 7 11 2 37 30 24 10 23 11 9 17 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000384981
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5149,062,313 - 149,062,409 (-)Ensembl
RefSeq Acc Id: NR_030310
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385149,062,313 - 149,062,409 (-)NCBI
GRCh375148,441,876 - 148,441,972 (-)RGD
Celera5144,523,931 - 144,524,027 (-)RGD
HuRef5143,587,150 - 143,587,246 (-)ENTREZGENE
CHM1_15147,874,371 - 147,874,467 (-)NCBI
T2T-CHM13v2.05149,597,158 - 149,597,254 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC MIR584 COSMIC
Ensembl Genes ENSG00000207714 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000384981 ENTREZGENE
GTEx ENSG00000207714 GTEx
HGNC ID HGNC:32840 ENTREZGENE
Human Proteome Map MIR584 Human Proteome Map
miRBase MI0003591 ENTREZGENE
NCBI Gene 693169 ENTREZGENE
PharmGKB PA164722881 PharmGKB
RNAcentral URS000006BE7D RNACentral
  URS0000576F83 RNACentral
  URS000066A55E RNACentral