MIR613 (microRNA 613) - Rat Genome Database

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Gene: MIR613 (microRNA 613) Homo sapiens
Analyze
Symbol: MIR613
Name: microRNA 613
RGD ID: 1603063
HGNC Page HGNC:32869
Description: Enables mRNA 3'-UTR binding activity and mRNA base-pairing post-transcriptional repressor activity. Involved in negative regulation of transport and regulation of gene expression.
Type: ncrna
RefSeq Status: PROVISIONAL
Previously known as: hsa-mir-613; MIRN613
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381212,764,649 - 12,764,743 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1212,764,649 - 12,764,743 (+)EnsemblGRCh38hg38GRCh38
GRCh371212,917,583 - 12,917,677 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361212,808,849 - 12,808,943 (+)NCBINCBI36hg18NCBI36
Celera1218,066,144 - 18,066,238 (+)NCBI
Cytogenetic Map12p13.1NCBI
HuRef1212,687,246 - 12,687,340 (+)NCBIHuRef
CHM1_11212,882,974 - 12,883,068 (+)NCBICHM1_1
T2T-CHM13v2.01212,638,215 - 12,638,309 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
progesterone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:16505370   PMID:21310851   PMID:23496987   PMID:24751522   PMID:26499784   PMID:26631045   PMID:26703210   PMID:26744345   PMID:27010138   PMID:27049311   PMID:27223438  
PMID:27534371   PMID:27545218   PMID:28351331   PMID:28415631   PMID:28701053   PMID:28718378   PMID:28901424   PMID:29067457   PMID:29187267   PMID:29339084   PMID:29551505   PMID:29744877  
PMID:29845707   PMID:30024598   PMID:30030888   PMID:30219232   PMID:30478856   PMID:31019537   PMID:31075412   PMID:31122697   PMID:31513352   PMID:31859457   PMID:31859543   PMID:31877552  
PMID:32633345   PMID:32726126   PMID:33107401   PMID:33294032   PMID:33398375   PMID:33760215   PMID:33849377   PMID:34101492   PMID:34255617   PMID:34268963   PMID:34516335   PMID:35435110  
PMID:35603775   PMID:35706002  


Genomics

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
NR1H3hsa-miR-613Mirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23496987

Predicted Targets
Summary Value
Count of predictions:13340
Count of gene targets:5692
Count of transcripts:10674
Interacting mature miRNAs:hsa-miR-613
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 2 33 3 9 9 3 4 6
Low 57 26 35 16 210 19 62 42 88 40 86 102 4 7 24 2
Below cutoff 30 25 15 4 31 5 41 10 30 5 26 28 13 21

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000385248
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1212,764,649 - 12,764,743 (+)Ensembl
RefSeq Acc Id: NR_030344
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381212,764,649 - 12,764,743 (+)NCBI
GRCh371212,917,583 - 12,917,677 (+)RGD
Celera1218,066,144 - 18,066,238 (+)RGD
HuRef1212,687,246 - 12,687,340 (+)RGD
CHM1_11212,882,974 - 12,883,068 (+)NCBI
T2T-CHM13v2.01212,638,215 - 12,638,309 (+)NCBI
Sequence:

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 12p13.2-12.3(chr12:12363649-15280588)x1 copy number loss See cases [RCV000135331] Chr12:12363649..15280588 [GRCh38]
Chr12:12514722..15433522 [GRCh37]
Chr12:12405989..15324789 [NCBI36]
Chr12:12p13.2-12.3
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:121255-34603274)x3 copy number gain See cases [RCV000136611] Chr12:121255..34603274 [GRCh38]
Chr12:282465..34756209 [GRCh37]
Chr12:100682..34647476 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.33-12.3(chr12:2871741-14987348)x3 copy number gain See cases [RCV000137694] Chr12:2871741..14987348 [GRCh38]
Chr12:2980907..15140282 [GRCh37]
Chr12:2851168..15031549 [NCBI36]
Chr12:12p13.33-12.3
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:121271-34603261)x3 copy number gain See cases [RCV000139052] Chr12:121271..34603261 [GRCh38]
Chr12:282465..34756196 [GRCh37]
Chr12:100698..34647463 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:54427-34608071)x4 copy number gain See cases [RCV000139787] Chr12:54427..34608071 [GRCh38]
Chr12:282465..34761006 [GRCh37]
Chr12:33854..34652273 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.33-12.2(chr12:1258274-20657577)x3 copy number gain See cases [RCV000141905] Chr12:1258274..20657577 [GRCh38]
Chr12:1367440..20810511 [GRCh37]
Chr12:1237701..20701778 [NCBI36]
Chr12:12p13.33-12.2
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:64620-34682902)x4 copy number gain See cases [RCV000142149] Chr12:64620..34682902 [GRCh38]
Chr12:173786..34835837 [GRCh37]
Chr12:44047..34727104 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.2-12.3(chr12:11121039-15908154)x1 copy number loss See cases [RCV000142882] Chr12:11121039..15908154 [GRCh38]
Chr12:11273638..16061088 [GRCh37]
Chr12:11164905..15952355 [NCBI36]
Chr12:12p13.2-12.3
likely pathogenic
GRCh38/hg38 12p13.2-13.1(chr12:11771233-13547775)x1 copy number loss See cases [RCV000050816] Chr12:11771233..13547775 [GRCh38]
Chr12:11924167..13700709 [GRCh37]
Chr12:11815434..13591976 [NCBI36]
Chr12:12p13.2-13.1
pathogenic
GRCh38/hg38 12p13.33-11.22(chr12:121055-28415184)x1 copy number loss See cases [RCV000052776] Chr12:121055..28415184 [GRCh38]
Chr12:282465..28568117 [GRCh37]
Chr12:100482..28459384 [NCBI36]
Chr12:12p13.33-11.22
pathogenic
GRCh38/hg38 12p13.2-12.3(chr12:12388842-15540422)x1 copy number loss See cases [RCV000052780] Chr12:12388842..15540422 [GRCh38]
Chr12:12541776..15693356 [GRCh37]
Chr12:12433043..15584623 [NCBI36]
Chr12:12p13.2-12.3
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:77187-34380176)x3 copy number gain See cases [RCV000053660] Chr12:77187..34380176 [GRCh38]
Chr12:282465..34533111 [GRCh37]
Chr12:56614..34424378 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.33-12.1(chr12:80412-25470329)x3 copy number gain See cases [RCV000053662] Chr12:80412..25470329 [GRCh38]
Chr12:282465..25623263 [GRCh37]
Chr12:59839..25514530 [NCBI36]
Chr12:12p13.33-12.1
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:212976-33926913)x4 copy number gain See cases [RCV000053666] Chr12:212976..33926913 [GRCh38]
Chr12:322142..34079848 [GRCh37]
Chr12:192403..33971115 [NCBI36]
Chr12:12p13.33-11.1
pathogenic

Additional Information

Database Acc Id Source(s)
COSMIC MIR613 COSMIC
Ensembl Genes ENSG00000207983 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000385248 ENTREZGENE
GTEx ENSG00000207983 GTEx
HGNC ID HGNC:32869 ENTREZGENE
Human Proteome Map MIR613 Human Proteome Map
miRBase MI0003626 ENTREZGENE
NCBI Gene 693198 ENTREZGENE
PharmGKB PA164722909 PharmGKB
RNAcentral URS000075B7E4 RNACentral
  URS000075EF41 RNACentral