HSP90AB2P (heat shock protein 90 alpha family class B member 2, pseudogene) - Rat Genome Database

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Gene: HSP90AB2P (heat shock protein 90 alpha family class B member 2, pseudogene) Homo sapiens
Analyze
No known orthologs.
Symbol: HSP90AB2P
Name: heat shock protein 90 alpha family class B member 2, pseudogene
RGD ID: 1602950
HGNC Page HGNC:32537
Description: Predicted to enable ATP binding activity; disordered domain specific binding activity; and unfolded protein binding activity. Predicted to be involved in cellular response to heat; protein folding; and protein stabilization. Located in extracellular exosome.
Type: pseudo (Ensembl: transcribed_processed_pseudogene)
RefSeq Status: INFERRED
Previously known as: heat shock protein 90kDa alpha family class B member 2, pseudogene; HSP90BB
RGD Orthologs
Alliance Genes
More Info homologs ...
Related Functional Gene: HSP90AB1  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38413,336,387 - 13,338,931 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl413,336,482 - 13,338,657 (+)EnsemblGRCh38hg38GRCh38
GRCh37413,338,011 - 13,340,555 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36412,944,135 - 12,949,023 (+)NCBINCBI36Build 36hg18NCBI36
Celera413,801,251 - 13,806,138 (+)NCBICelera
Cytogenetic Map4p15.33NCBI
HuRef412,675,869 - 12,678,397 (+)NCBIHuRef
CHM1_1413,336,585 - 13,339,113 (+)NCBICHM1_1
T2T-CHM13v2.0413,316,068 - 13,318,613 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16269234   PMID:16288044   PMID:16507910   PMID:20811636   PMID:21145461   PMID:21726808   PMID:21873635   PMID:22658674   PMID:22863883   PMID:22939629   PMID:23251661   PMID:23349634  
PMID:23533145   PMID:24347629   PMID:25921289   PMID:25963833   PMID:26167880   PMID:26831064   PMID:26972000   PMID:27025967   PMID:27173435   PMID:28027390   PMID:28302793   PMID:28515276  
PMID:28739485   PMID:29229926   PMID:29467282   PMID:29845934   PMID:30442766   PMID:30455355   PMID:30619736   PMID:30833792   PMID:31091453   PMID:31527615   PMID:31586073   PMID:31980649  
PMID:32344865   PMID:32466590   PMID:32707033   PMID:32807901   PMID:33567341   PMID:33961781   PMID:34650049   PMID:34732716   PMID:34901782   PMID:35256949   PMID:35271311   PMID:35384245  
PMID:35439318   PMID:35546148   PMID:35941108   PMID:35944360   PMID:35973513   PMID:36042349   PMID:36114006   PMID:36215168   PMID:36282215   PMID:36424410   PMID:37689310   PMID:37827155  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:542
Count of miRNA genes:343
Interacting mature miRNAs:359
Transcripts:ENST00000382444, ENST00000507090, ENST00000602906
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
WI-8585  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4p15.33UniSTS
Cytogenetic Map6p12UniSTS
Cytogenetic Map15q22.1UniSTS
Whitehead-YAC Contig Map4 UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 2 4 1
Low 90 80 182 53 425 53 313 59 136 142 417 287 4 21 110 1
Below cutoff 2257 2695 1430 472 1285 315 3950 2059 3366 194 992 1271 163 1160 2639 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000507090
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl413,336,482 - 13,338,657 (+)Ensembl
RefSeq Acc Id: ENST00000602906
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl413,333,414 - 13,338,302 (+)Ensembl
RefSeq Acc Id: NR_003132
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh37413,335,037 - 13,339,925 (+)RGD
Build 36412,944,135 - 12,949,023 (+)NCBI Archive
Celera413,801,251 - 13,806,138 (+)RGD
HuRef412,672,885 - 12,677,772 (+)RGD
CHM1_1413,275,111 - 13,280,000 (+)NCBI
Protein Sequences
GenBank Protein AAX38250 (Get FASTA)   NCBI Sequence Viewer  
  Q58FF8 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q58FF8-F1-model_v2 AlphaFold Q58FF8 1-381 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:32537 AgrOrtholog
COSMIC HSP90AB2P COSMIC
Ensembl Genes ENSG00000205940 Ensembl, ENTREZGENE
Gene3D-CATH 1.20.120.790 UniProtKB/Swiss-Prot
  3.30.565.10 UniProtKB/Swiss-Prot
  3.40.50.11260 UniProtKB/Swiss-Prot
GTEx ENSG00000205940 GTEx
HGNC ID HGNC:32537 ENTREZGENE
Human Proteome Map HSP90AB2P Human Proteome Map
InterPro HATPase_C_sf UniProtKB/Swiss-Prot
  HSP90_C UniProtKB/Swiss-Prot
  Hsp90_fam UniProtKB/Swiss-Prot
  Hsp90_N UniProtKB/Swiss-Prot
  Ribosomal_S5_D2-typ_fold UniProtKB/Swiss-Prot
NCBI Gene 391634 ENTREZGENE
PANTHER HEAT SHOCK PROTEIN HSP 90-BETA 2-RELATED UniProtKB/Swiss-Prot
  PTHR11528 UniProtKB/Swiss-Prot
Pfam HSP90 UniProtKB/Swiss-Prot
PharmGKB PA143485495 PharmGKB
PRINTS HEATSHOCK90 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF110942 UniProtKB/Swiss-Prot
  SSF54211 UniProtKB/Swiss-Prot
  SSF55874 UniProtKB/Swiss-Prot
UniProt H90B2_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-28 HSP90AB2P  heat shock protein 90 alpha family class B member 2, pseudogene    heat shock protein 90kDa alpha family class B member 2, pseudogene  Symbol and/or name change 5135510 APPROVED
2015-11-24 HSP90AB2P  heat shock protein 90kDa alpha family class B member 2, pseudogene    heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene  Symbol and/or name change 5135510 APPROVED
2011-07-27 HSP90AB2P  heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene  HSP90AB2P  heat shock protein 90kDa alpha (cytosolic), class B member 2 (pseudogene)  Symbol and/or name change 5135510 APPROVED