SNORA75 (small nucleolar RNA, H/ACA box 75) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: SNORA75 (small nucleolar RNA, H/ACA box 75) Homo sapiens
Analyze
Symbol: SNORA75
Name: small nucleolar RNA, H/ACA box 75
RGD ID: 1602778
HGNC Page HGNC:32661
Description: Predicted to be involved in RNA processing. Predicted to be located in nucleolus; INTERACTS WITH (-)-alpha-phellandrene; (-)-epigallocatechin 3-gallate; alpha-phellandrene.
Type: snorna
RefSeq Status: VALIDATED
Previously known as: SNORA75A; U23
RGD Orthologs
Mouse
Rat
Dog
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,455,800 - 231,455,936 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,455,800 - 231,455,936 (-)EnsemblGRCh38hg38GRCh38
GRCh372232,320,511 - 232,320,647 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362232,028,755 - 232,028,891 (-)NCBINCBI36Build 36hg18NCBI36
Celera2226,096,864 - 226,097,000 (-)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2224,161,994 - 224,162,130 (-)NCBIHuRef
CHM1_12232,326,327 - 232,326,463 (-)NCBICHM1_1
T2T-CHM13v2.02231,940,239 - 231,940,375 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (HEP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients. Xiong Y, etal., Emerg Microbes Infect. 2020 Dec;9(1):761-770. doi: 10.1080/22221751.2020.1747363.
Additional References at PubMed
PMID:9182768   PMID:15199136   PMID:16381836   PMID:19446021   PMID:33852194  


Genomics

Comparative Map Data
SNORA75
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,455,800 - 231,455,936 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,455,800 - 231,455,936 (-)EnsemblGRCh38hg38GRCh38
GRCh372232,320,511 - 232,320,647 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362232,028,755 - 232,028,891 (-)NCBINCBI36Build 36hg18NCBI36
Celera2226,096,864 - 226,097,000 (-)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2224,161,994 - 224,162,130 (-)NCBIHuRef
CHM1_12232,326,327 - 232,326,463 (-)NCBICHM1_1
T2T-CHM13v2.02231,940,239 - 231,940,375 (-)NCBIT2T-CHM13v2.0
Snora75
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39186,278,892 - 86,279,007 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl186,278,891 - 86,279,023 (-)EnsemblGRCm39 Ensembl
GRCm38186,351,170 - 86,351,285 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl186,351,169 - 86,351,301 (-)EnsemblGRCm38mm10GRCm38
MGSCv37188,247,745 - 88,247,860 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera189,316,075 - 89,316,190 (-)NCBICelera
Cytogenetic Map1C5NCBI
cM Map143.94NCBI
LOC120094881
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8994,448,219 - 94,448,355 (-)NCBIGRCr8
mRatBN7.2987,000,248 - 87,000,384 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl987,000,248 - 87,000,384 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0 Ensembl993,369,779 - 93,369,915 (-)NCBIRnor6.0rn6Rnor6.0
Cytogenetic Map9q35NCBI
LOC119866031
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha2543,890,934 - 43,891,068 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02543,589,455 - 43,589,589 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2543,589,455 - 43,589,589 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12543,517,258 - 43,517,392 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02543,360,100 - 43,360,234 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02543,515,814 - 43,515,948 (-)NCBIUU_Cfam_GSD_1.0


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2q36.3-37.3(chr2:228723579-241404867)x3 copy number gain See cases [RCV000134169] Chr2:228723579..241404867 [GRCh38]
Chr2:229588295..242344282 [GRCh37]
Chr2:229296539..241992955 [NCBI36]
Chr2:2q36.3-37.3
pathogenic
GRCh38/hg38 2q34-37.3(chr2:210579676-242126245)x3 copy number gain See cases [RCV000135934] Chr2:210579676..242126245 [GRCh38]
Chr2:211444400..243059659 [GRCh37]
Chr2:211152645..242717069 [NCBI36]
Chr2:2q34-37.3
pathogenic
GRCh38/hg38 2q36.3-37.2(chr2:228014149-234976424)x3 copy number gain See cases [RCV000136967] Chr2:228014149..234976424 [GRCh38]
Chr2:228878865..235885068 [GRCh37]
Chr2:228587109..235549807 [NCBI36]
Chr2:2q36.3-37.2
pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:189436149-241841232)x3 copy number gain See cases [RCV000142307] Chr2:189436149..241841232 [GRCh38]
Chr2:190300875..242783384 [GRCh37]
Chr2:190009120..242432057 [NCBI36]
Chr2:2q32.2-37.3
pathogenic
GRCh38/hg38 2q35-37.3(chr2:218101759-242126245)x3 copy number gain See cases [RCV000143216] Chr2:218101759..242126245 [GRCh38]
Chr2:218966482..243059659 [GRCh37]
Chr2:218674727..242717069 [NCBI36]
Chr2:2q35-37.3
pathogenic
GRCh38/hg38 2q32.3-37.3(chr2:194898783-236473913)x3 copy number gain See cases [RCV000051119] Chr2:194898783..236473913 [GRCh38]
Chr2:195763507..237382556 [GRCh37]
Chr2:195471752..237047295 [NCBI36]
Chr2:2q32.3-37.3
pathogenic
GRCh38/hg38 2q36.3-37.3(chr2:226978129-236886599)x1 copy number loss See cases [RCV000052637] Chr2:226978129..236886599 [GRCh38]
Chr2:227842845..237795242 [GRCh37]
Chr2:227551089..237459981 [NCBI36]
Chr2:2q36.3-37.3
pathogenic
GRCh38/hg38 2q36.3-37.2(chr2:227343278-235339168)x1 copy number loss See cases [RCV000052638] Chr2:227343278..235339168 [GRCh38]
Chr2:228207994..236247812 [GRCh37]
Chr2:227916238..235912551 [NCBI36]
Chr2:2q36.3-37.2
pathogenic
GRCh38/hg38 2q37.1-37.3(chr2:231375505-242065208)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052639]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052639]|See cases [RCV000052639] Chr2:231375505..242065208 [GRCh38]
Chr2:232240216..243007359 [GRCh37]
Chr2:231948460..242656032 [NCBI36]
Chr2:2q37.1-37.3
pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:188818195-242065208)x3 copy number gain See cases [RCV000052958] Chr2:188818195..242065208 [GRCh38]
Chr2:189682921..243007359 [GRCh37]
Chr2:189391166..242656032 [NCBI36]
Chr2:2q32.2-37.3
pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:190310736-241892770)x3 copy number gain See cases [RCV000052959] Chr2:190310736..241892770 [GRCh38]
Chr2:191175462..242834921 [GRCh37]
Chr2:190883707..242483594 [NCBI36]
Chr2:2q32.2-37.3
pathogenic
GRCh38/hg38 2q32.3-37.3(chr2:193122313-241074980)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052960]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052960]|See cases [RCV000052960] Chr2:193122313..241074980 [GRCh38]
Chr2:193987039..242014395 [GRCh37]
Chr2:193695284..241663068 [NCBI36]
Chr2:2q32.3-37.3
pathogenic
GRCh38/hg38 2q36.1-37.3(chr2:223992431-242126245)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052972]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052972]|See cases [RCV000052972] Chr2:223992431..242126245 [GRCh38]
Chr2:224857148..243059659 [GRCh37]
Chr2:224565392..242717069 [NCBI36]
Chr2:2q36.1-37.3
pathogenic
GRCh38/hg38 2q36.3-37.3(chr2:227803148-242086301)x3 copy number gain See cases [RCV000052973] Chr2:227803148..242086301 [GRCh38]
Chr2:228667864..243028452 [GRCh37]
Chr2:228376108..242677125 [NCBI36]
Chr2:2q36.3-37.3
pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:126
Count of miRNA genes:122
Interacting mature miRNAs:123
Transcripts:ENST00000384158
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH65048  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379139,707,751 - 139,707,856UniSTSGRCh37
GRCh372232,321,719 - 232,321,822UniSTSGRCh37
Build 362232,029,963 - 232,030,066RGDNCBI36
Celera9110,221,518 - 110,221,623UniSTS
Celera2226,098,072 - 226,098,175RGD
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map2q37.1UniSTS
HuRef9109,167,013 - 109,167,118UniSTS
HuRef2224,163,202 - 224,163,305UniSTS
RH120232  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372232,320,813 - 232,321,139UniSTSGRCh37
Build 362232,029,057 - 232,029,383RGDNCBI36
Celera2226,097,166 - 226,097,492RGD
Cytogenetic Map2q37.1UniSTS
HuRef2224,162,296 - 224,162,622UniSTS
TNG Radiation Hybrid Map2129386.0UniSTS
NCL  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372232,322,358 - 232,322,478UniSTSGRCh37
Celera2226,098,711 - 226,098,831UniSTS
HuRef2224,163,841 - 224,163,961UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 34 13 48 36 247 37 22 14 16 11 72 25 9
Low 2211 1726 1575 521 1200 378 3115 1167 2334 294 1303 1487 154 1099 1693 4
Below cutoff 125 724 63 42 198 29 599 538 840 43 46 47 13 66 526

Sequence


RefSeq Acc Id: ENST00000384158
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2231,455,800 - 231,455,936 (-)Ensembl
RefSeq Acc Id: NR_002921
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382231,455,800 - 231,455,936 (-)NCBI
GRCh372232,320,511 - 232,320,647 (-)RGD
Build 362232,028,755 - 232,028,891 (-)NCBI Archive
Celera2226,096,864 - 226,097,000 (-)RGD
HuRef2224,161,994 - 224,162,130 (-)ENTREZGENE
CHM1_12232,326,327 - 232,326,463 (-)NCBI
T2T-CHM13v2.02231,940,239 - 231,940,375 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC SNORA75 COSMIC
Ensembl Genes ENSG00000206885 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000384158 ENTREZGENE
GTEx ENSG00000206885 GTEx
HGNC ID HGNC:32661 ENTREZGENE
Human Proteome Map SNORA75 Human Proteome Map
NCBI Gene 654321 ENTREZGENE
PharmGKB PA144596277 PharmGKB
RNAcentral URS00004640CB RNACentral