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Gene: POLR1E (RNA polymerase I subunit E) Homo sapiens
Symbol: POLR1E
Name: RNA polymerase I subunit E
Description: Predicted to contribute to RNA polymerase I activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly; nucleolar large rRNA transcription by RNA polymerase I; and transcription elongation from RNA polymerase I promoter. Localizes to the fibrillar center and nucleoplasm; PARTICIPATES IN purine metabolic pathway; pyrimidine metabolic pathway; RNA polymerase I transcription pathway; INTERACTS WITH 2-hydroxypropanoic acid; aflatoxin B1; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA-directed RNA polymerase I subunit E; DNA-directed RNA polymerase I subunit RPA49; FLJ13390; FLJ13970; FLJ43482; PAF53; polymerase (RNA) I associated factor 1; polymerase (RNA) I polypeptide E; polymerase (RNA) I polypeptide E, 53kDa; polymerase (RNA) I subunit E; PRAF1; RNA polymerase I associated factor 53; RNA polymerase I subunit A49; RNA polymerase I-associated factor 1; RNA polymerase I-associated factor 53; RP11-405L18.3
Mus musculus (house mouse) : Polr1e (polymerase (RNA) I polypeptide E)  MGI  Alliance
Rattus norvegicus (Norway rat) : Polr1e (RNA polymerase I subunit E)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Polr1e (RNA polymerase I subunit E)
Pan paniscus (bonobo/pygmy chimpanzee) : POLR1E (RNA polymerase I subunit E)
Canis lupus familiaris (dog) : POLR1E (RNA polymerase I subunit E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Polr1e (RNA polymerase I subunit E)
Sus scrofa (pig) : POLR1E (RNA polymerase I subunit E)
Chlorocebus sabaeus (green monkey) : POLR1E (RNA polymerase I subunit E)
Heterocephalus glaber (naked mole-rat) : Polr1e (RNA polymerase I subunit E)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl937,485,948 - 37,503,697 (+)Ensembl
GRCh38937,485,935 - 37,503,697 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37937,485,945 - 37,503,694 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36937,475,945 - 37,493,693 (+)NCBINCBI36hg18NCBI36
Celera937,419,179 - 37,436,922 (+)NCBI
Cytogenetic Map9p13.2NCBI
HuRef937,437,994 - 37,455,737 (+)NCBIHuRef
CHM1_1937,487,637 - 37,505,394 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on POLR1E
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1602318
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.