Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane | multiple interactions | ISO | Endod1 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:19414516 | 1,2-dimethylhydrazine | multiple interactions | ISO | Endod1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ENDOD1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Endod1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ENDOD1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of ENDOD1 mRNA | CTD | PMID:31614463 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | EXP | | 6480464 | Dihydrotestosterone results in increased expression of ENDOD1 mRNA | CTD | PMID:29581250 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Endod1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ENDOD1 mRNA | CTD | PMID:19770486 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ENDOD1 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Endod1 (Mus musculus) | 6480464 | AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of ENDOD1 mRNA] | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Endod1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ENDOD1 mRNA | CTD | PMID:15034205 and PMID:19465110 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Endod1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ENDOD1 mRNA | CTD | PMID:21570461 | 2,4,6-tribromophenol | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31675489 | 2-butoxyethanol | increases expression | ISO | Endod1 (Mus musculus) | 6480464 | n-butoxyethanol results in increased expression of ENDOD1 mRNA | CTD | PMID:19812364 | 2-hydroxypropanoic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of ENDOD1 mRNA | CTD | PMID:30851411 | 3',5'-cyclic AMP | multiple interactions | ISO | Endod1 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:19414516 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | Endod1 (Mus musculus) | 6480464 | tetrabromobisphenol A results in decreased expression of ENDOD1 mRNA | CTD | PMID:25172293 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | EXP | | 6480464 | tetrabromobisphenol A results in decreased expression of ENDOD1 protein | CTD | PMID:31675489 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Endod1 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of ENDOD1 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of ENDOD1 mRNA | CTD | PMID:24780913 | aflatoxin B1 | decreases expression | ISO | Endod1 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of ENDOD1 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases methylation | EXP | | 6480464 | Aflatoxin B1 results in increased methylation of ENDOD1 intron | CTD | PMID:30157460 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of ENDOD1 mRNA | CTD | PMID:22100608 | benzo[a]pyrene | decreases expression | ISO | Endod1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ENDOD1 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ENDOD1 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of ENDOD1 intron | CTD | PMID:30157460 | benzo[a]pyrene | increases expression | ISO | Endod1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ENDOD1 mRNA | CTD | PMID:15034205 and PMID:22228805 | benzo[a]pyrene | multiple interactions | ISO | Endod1 (Mus musculus) | 6480464 | AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of ENDOD1 mRNA] | CTD | PMID:15034205 | bilirubin IXalpha | decreases expression | EXP | | 6480464 | Bilirubin results in decreased expression of ENDOD1 mRNA | CTD | PMID:20196124 | bisphenol A | decreases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ENDOD1 mRNA | CTD | PMID:25181051 and PMID:26982218 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of ENDOD1 gene | CTD | PMID:31601247 | bisphenol A | increases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of ENDOD1 mRNA | CTD | PMID:32145629 | cadmium dichloride | affects expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | Cadmium Chloride affects the expression of ENDOD1 mRNA | CTD | PMID:22110744 | caffeine | decreases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | Caffeine results in decreased expression of ENDOD1 mRNA | CTD | PMID:20864626 | cannabidiol | decreases expression | EXP | | 6480464 | Cannabidiol results in decreased expression of ENDOD1 protein | CTD | PMID:34122009 | carbon nanotube | decreases expression | ISO | Endod1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of ENDOD1 mRNA | CTD | PMID:25620056 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ENDOD1 gene] | CTD | PMID:28238834 | choline | multiple interactions | ISO | Endod1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ENDOD1 gene | CTD | PMID:20938992 | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of ENDOD1 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of ENDOD1 mRNA | CTD | PMID:27392435 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of ENDOD1 mRNA | CTD | PMID:19320972 | cobalt dichloride | increases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | cobaltous chloride results in increased expression of ENDOD1 mRNA | CTD | PMID:24386269 | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of ENDOD1 mRNA | CTD | PMID:19549813 | coumestrol | increases expression | EXP | | 6480464 | Coumestrol results in increased expression of ENDOD1 mRNA | CTD | PMID:19167446 | coumestrol | multiple interactions | EXP | | 6480464 | [Coumestrol co-treated with 2 more ... | CTD | PMID:19167446 | Cuprizon | decreases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of ENDOD1 mRNA | CTD | PMID:26577399 and PMID:27523638 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of ENDOD1 mRNA | CTD | PMID:25562108 | decabromodiphenyl ether | decreases expression | EXP | | 6480464 | decabromobiphenyl ether results in decreased expression of ENDOD1 protein | CTD | PMID:31675489 | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of ENDOD1 mRNA | CTD | PMID:12782123 | dibutyl phthalate | increases expression | ISO | Endod1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of ENDOD1 mRNA | CTD | PMID:21266533 | dioxygen | multiple interactions | ISO | Endod1 (Mus musculus) | 6480464 | Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of ENDOD1 mRNA] | CTD | PMID:22629407 | dioxygen | increases expression | ISO | Endod1 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of ENDOD1 mRNA | CTD | PMID:22629407 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ENDOD1 mRNA | CTD | PMID:27188386 | doxorubicin | increases expression | EXP | | 6480464 | Doxorubicin results in increased expression of ENDOD1 mRNA | CTD | PMID:30031762 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of ENDOD1 mRNA | CTD | PMID:29803840 | Enterolactone | multiple interactions | EXP | | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ENDOD1 mRNA | CTD | PMID:19167446 | entinostat | increases expression | EXP | | 6480464 | entinostat results in increased expression of ENDOD1 mRNA | CTD | PMID:27188386 | ethyl methanesulfonate | decreases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in decreased expression of ENDOD1 mRNA | CTD | PMID:23649840 | fenvalerate | increases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | fenvalerate results in increased expression of ENDOD1 mRNA | CTD | PMID:30307764 | folic acid | multiple interactions | ISO | Endod1 (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | folic acid | increases expression | ISO | Endod1 (Mus musculus) | 6480464 | Folic Acid results in increased expression of ENDOD1 mRNA | CTD | PMID:25629700 | glyphosate | increases expression | ISO | Endod1 (Mus musculus) | 6480464 | Glyphosate results in increased expression of ENDOD1 mRNA | CTD | PMID:35897073 | isoflavones | decreases expression | EXP | | 6480464 | Isoflavones results in decreased expression of ENDOD1 mRNA | CTD | PMID:17374662 | ivermectin | decreases expression | EXP | | 6480464 | Ivermectin results in decreased expression of ENDOD1 protein | CTD | PMID:32959892 | L-methionine | multiple interactions | ISO | Endod1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ENDOD1 gene | CTD | PMID:20938992 | lead(0) | affects expression | EXP | | 6480464 | Lead affects the expression of ENDOD1 mRNA | CTD | PMID:28903495 | methoxyacetic acid | decreases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | methoxyacetic acid results in decreased expression of ENDOD1 mRNA | CTD | PMID:20864626 | methyl methanesulfonate | decreases expression | EXP | | 6480464 | Methyl Methanesulfonate results in decreased expression of ENDOD1 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | methylmercuric chloride results in decreased expression of ENDOD1 mRNA | CTD | PMID:20864626 | Monobutylphthalate | decreases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | monobutyl phthalate results in decreased expression of ENDOD1 mRNA | CTD | PMID:20864626 | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of ENDOD1 mRNA | CTD | PMID:24810058 | N-nitrosodiethylamine | multiple interactions | ISO | Endod1 (Mus musculus) | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ENDOD1 mRNA | CTD | PMID:24535843 | nickel sulfate | decreases expression | EXP | | 6480464 | nickel sulfate results in decreased expression of ENDOD1 mRNA | CTD | PMID:22714537 | niclosamide | multiple interactions | EXP | | 6480464 | Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of ENDOD1 mRNA] | CTD | PMID:27542212 | paracetamol | affects expression | ISO | Endod1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ENDOD1 mRNA | CTD | PMID:17562736 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of ENDOD1 mRNA | CTD | PMID:25458485 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ENDOD1 mRNA | CTD | PMID:21420995 and PMID:29067470 | pentachlorophenol | increases expression | ISO | Endod1 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of ENDOD1 mRNA | CTD | PMID:23892564 | perfluorooctanoic acid | increases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | perfluorooctanoic acid results in increased expression of ENDOD1 mRNA | CTD | PMID:28511854 | phenobarbital | multiple interactions | ISO | Endod1 (Mus musculus) | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ENDOD1 mRNA and NR1I3 protein affects the reaction [Phenobarbital results in increased expression of ENDOD1 mRNA] | CTD | PMID:19482888 and PMID:24535843 | phenobarbital | affects expression | ISO | Endod1 (Mus musculus) | 6480464 | Phenobarbital affects the expression of ENDOD1 mRNA | CTD | PMID:23091169 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of ENDOD1 mRNA | CTD | PMID:19159669 | phenobarbital | increases expression | ISO | Endod1 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of ENDOD1 mRNA | CTD | PMID:19482888 | phenylmercury acetate | increases expression | EXP | | 6480464 | Phenylmercuric Acetate results in increased expression of ENDOD1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ENDOD1 mRNA | CTD | PMID:27188386 | pyrvinium | multiple interactions | EXP | | 6480464 | pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of ENDOD1 mRNA] | CTD | PMID:27542212 | quercetin | decreases expression | EXP | | 6480464 | Quercetin results in decreased expression of ENDOD1 mRNA | CTD | PMID:21632981 | rac-lactic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of ENDOD1 mRNA | CTD | PMID:30851411 | raloxifene | multiple interactions | EXP | | 6480464 | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ENDOD1 mRNA | CTD | PMID:19059307 | resveratrol | multiple interactions | EXP | | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of ENDOD1 mRNA | CTD | PMID:19167446 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of ENDOD1 mRNA | CTD | PMID:29955902 | rotenone | increases expression | ISO | Endod1 (Mus musculus) | 6480464 | Rotenone results in increased expression of ENDOD1 mRNA | CTD | PMID:32937126 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ENDOD1 mRNA | CTD | PMID:27188386 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of ENDOD1 mRNA | CTD | PMID:34032870 | sodium dichromate | affects expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | sodium bichromate affects the expression of ENDOD1 mRNA | CTD | PMID:22110744 | succimer | multiple interactions | ISO | Endod1 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of ENDOD1 mRNA and [Succimer co-treated with Magnetite Nanoparticles] affects the expression of ENDOD1 mRNA | CTD | PMID:21641980 and PMID:26378955 | sunitinib | increases expression | EXP | | 6480464 | Sunitinib results in increased expression of ENDOD1 mRNA | CTD | PMID:31533062 | tamoxifen | multiple interactions | EXP | | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in decreased expression of ENDOD1 mRNA | CTD | PMID:19059307 | tetrachloromethane | affects expression | ISO | Endod1 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of ENDOD1 mRNA | CTD | PMID:17484886 | thioacetamide | increases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of ENDOD1 mRNA | CTD | PMID:34492290 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of ENDOD1 mRNA | CTD | PMID:24935251 | triclosan | increases expression | EXP | | 6480464 | Triclosan results in increased expression of ENDOD1 mRNA | CTD | PMID:30510588 | Triptolide | increases expression | ISO | Endod1 (Mus musculus) | 6480464 | triptolide results in increased expression of ENDOD1 mRNA | CTD | PMID:32835833 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of ENDOD1 mRNA | CTD | PMID:23179753 more ... | vinclozolin | increases expression | ISO | Endod1 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of ENDOD1 mRNA | CTD | PMID:30207508 | |