ZC3H12C (zinc finger CCCH-type containing 12C) - Rat Genome Database

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Gene: ZC3H12C (zinc finger CCCH-type containing 12C) Homo sapiens
Analyze
Symbol: ZC3H12C
Name: zinc finger CCCH-type containing 12C
RGD ID: 1602083
HGNC Page HGNC:29362
Description: Predicted to enable RNA endonuclease activity and mRNA binding activity. Predicted to be active in cytoplasmic ribonucleoprotein granule and nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: KIAA1726; MCP induced protein 3; MCP-induced protein 3; MCPIP3; probable ribonuclease ZC3H12C; zinc finger CCCH domain-containing protein 12C
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811110,093,392 - 110,171,841 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11110,093,392 - 110,171,841 (+)EnsemblGRCh38hg38GRCh38
GRCh3711109,964,118 - 110,042,566 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611109,469,297 - 109,547,776 (+)NCBINCBI36Build 36hg18NCBI36
Celera11107,117,954 - 107,196,032 (+)NCBICelera
Cytogenetic Map11q22.3NCBI
HuRef11105,888,503 - 105,966,975 (+)NCBIHuRef
CHM1_111109,847,682 - 109,925,765 (+)NCBICHM1_1
T2T-CHM13v2.011110,103,649 - 110,181,661 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11214970   PMID:14702039   PMID:17114934   PMID:17903301   PMID:18178554   PMID:20379614   PMID:21873635   PMID:21903422   PMID:23360436   PMID:25391383   PMID:26673895   PMID:29507755  
PMID:32296183   PMID:33277362   PMID:33961781   PMID:34215755  


Genomics

Comparative Map Data
ZC3H12C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811110,093,392 - 110,171,841 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11110,093,392 - 110,171,841 (+)EnsemblGRCh38hg38GRCh38
GRCh3711109,964,118 - 110,042,566 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611109,469,297 - 109,547,776 (+)NCBINCBI36Build 36hg18NCBI36
Celera11107,117,954 - 107,196,032 (+)NCBICelera
Cytogenetic Map11q22.3NCBI
HuRef11105,888,503 - 105,966,975 (+)NCBIHuRef
CHM1_111109,847,682 - 109,925,765 (+)NCBICHM1_1
T2T-CHM13v2.011110,103,649 - 110,181,661 (+)NCBIT2T-CHM13v2.0
Zc3h12c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39952,020,869 - 52,080,028 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl952,022,644 - 52,079,872 (-)EnsemblGRCm39 Ensembl
GRCm38952,109,569 - 52,168,730 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl952,111,344 - 52,168,572 (-)EnsemblGRCm38mm10GRCm38
MGSCv37951,920,090 - 51,976,216 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36951,864,350 - 51,920,476 (-)NCBIMGSCv36mm8
Celera949,387,963 - 49,443,774 (-)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map928.62NCBI
Zc3h12c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8861,340,446 - 61,404,932 (-)NCBIGRCr8
mRatBN7.2852,443,791 - 52,508,643 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl852,448,320 - 52,504,315 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx857,998,889 - 58,051,329 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0856,277,867 - 56,330,309 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0854,142,109 - 54,194,547 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0856,639,439 - 56,696,968 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl856,641,808 - 56,696,968 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0855,220,679 - 55,281,457 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4855,478,499 - 55,531,853 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera851,973,896 - 52,028,289 (-)NCBICelera
Cytogenetic Map8q24NCBI
Zc3h12c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541212,020,201 - 12,086,331 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541212,015,252 - 12,086,331 (+)NCBIChiLan1.0ChiLan1.0
ZC3H12C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29110,835,310 - 110,913,742 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111111,929,305 - 112,007,741 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011104,975,798 - 105,054,382 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111108,859,581 - 108,900,311 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11108,859,581 - 108,899,858 (+)Ensemblpanpan1.1panPan2
ZC3H12C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1522,666,321 - 22,756,089 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl522,669,947 - 22,747,506 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha522,585,304 - 22,675,105 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0522,691,927 - 22,781,615 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl522,697,289 - 22,768,555 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1522,750,064 - 22,839,638 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0522,650,570 - 22,740,138 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0522,701,215 - 22,790,838 (-)NCBIUU_Cfam_GSD_1.0
Zc3h12c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494792,567,382 - 92,631,663 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366124,076,205 - 4,137,860 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366124,076,155 - 4,138,227 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZC3H12C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl938,138,004 - 38,207,027 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1938,133,440 - 38,209,365 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2942,847,525 - 42,918,884 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZC3H12C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11101,452,994 - 101,531,680 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1101,453,473 - 101,525,596 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604324,420,101 - 24,499,287 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zc3h12c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247845,113,931 - 5,173,198 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247845,113,608 - 5,179,490 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZC3H12C
32 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q22.1-25(chr11:100348599-135040246)x3 copy number gain See cases [RCV000053638] Chr11:100348599..135040246 [GRCh38]
Chr11:100219331..134910140 [GRCh37]
Chr11:99724541..134415350 [NCBI36]
Chr11:11q22.1-25
pathogenic
NM_033390.1(ZC3H12C):c.442A>G (p.Thr148Ala) single nucleotide variant Malignant melanoma [RCV000069155] Chr11:110137083 [GRCh38]
Chr11:110007808 [GRCh37]
Chr11:109513018 [NCBI36]
Chr11:11q22.3
not provided
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11q22.3(chr11:109558847-110079020)x3 copy number gain See cases [RCV000511370] Chr11:109558847..110079020 [GRCh37]
Chr11:11q22.3
uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
NM_033390.2(ZC3H12C):c.527A>G (p.Glu176Gly) single nucleotide variant Inborn genetic diseases [RCV003267526] Chr11:110137168 [GRCh38]
Chr11:110007893 [GRCh37]
Chr11:11q22.3
uncertain significance
GRCh37/hg19 11q13.4-23.3(chr11:71588805-116680918)x3 copy number gain not provided [RCV000683374] Chr11:71588805..116680918 [GRCh37]
Chr11:11q13.4-23.3
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11q14.1-23.2(chr11:80053454-113316236)x1 copy number loss not provided [RCV000737595] Chr11:80053454..113316236 [GRCh37]
Chr11:11q14.1-23.2
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11q22.3-23.3(chr11:104101411-116680918)x1 copy number loss not provided [RCV000848741] Chr11:104101411..116680918 [GRCh37]
Chr11:11q22.3-23.3
pathogenic
GRCh37/hg19 11q22.3-23.2(chr11:103320065-114349787)x1 copy number loss not provided [RCV001006439] Chr11:103320065..114349787 [GRCh37]
Chr11:11q22.3-23.2
pathogenic
GRCh37/hg19 11q22.3-23.3(chr11:105699599-114524876)x1 copy number loss not provided [RCV001006445] Chr11:105699599..114524876 [GRCh37]
Chr11:11q22.3-23.3
pathogenic
NM_033390.2(ZC3H12C):c.355C>G (p.Gln119Glu) single nucleotide variant X-linked Alport syndrome [RCV001563714] Chr11:110136996 [GRCh38]
Chr11:110007721 [GRCh37]
Chr11:11q22.3
uncertain significance
NC_000011.9:g.(?_94153285)_(111965700_?)del deletion Ataxia-telangiectasia syndrome [RCV001389105] Chr11:94153285..111965700 [GRCh37]
Chr11:11q21-23.1
pathogenic
NC_000011.9:g.104288964_134937416dup duplication Distal trisomy 11q [RCV001250234] Chr11:104288964..134937416 [GRCh37]
Chr11:11q22.3-25
pathogenic
GRCh37/hg19 11q14.1-23.3(chr11:85422071-118022671)x1 copy number loss not provided [RCV001832892] Chr11:85422071..118022671 [GRCh37]
Chr11:11q14.1-23.3
uncertain significance
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25
pathogenic
NM_033390.2(ZC3H12C):c.398G>T (p.Arg133Leu) single nucleotide variant Inborn genetic diseases [RCV003262774] Chr11:110137039 [GRCh38]
Chr11:110007764 [GRCh37]
Chr11:11q22.3
uncertain significance
GRCh37/hg19 11q22.3-23.3(chr11:109328787-116414966)x1 copy number loss not provided [RCV002474547] Chr11:109328787..116414966 [GRCh37]
Chr11:11q22.3-23.3
pathogenic
NM_033390.2(ZC3H12C):c.380A>T (p.Glu127Val) single nucleotide variant Inborn genetic diseases [RCV002773383] Chr11:110137021 [GRCh38]
Chr11:110007746 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.712G>T (p.Val238Leu) single nucleotide variant Inborn genetic diseases [RCV002689739] Chr11:110137353 [GRCh38]
Chr11:110008078 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.469G>A (p.Asp157Asn) single nucleotide variant Inborn genetic diseases [RCV002684185] Chr11:110137110 [GRCh38]
Chr11:110007835 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.1146C>G (p.Asp382Glu) single nucleotide variant Inborn genetic diseases [RCV002773930] Chr11:110159488 [GRCh38]
Chr11:110030213 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.769A>G (p.Met257Val) single nucleotide variant Inborn genetic diseases [RCV002684363] Chr11:110137410 [GRCh38]
Chr11:110008135 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.2197C>T (p.His733Tyr) single nucleotide variant Inborn genetic diseases [RCV002946323] Chr11:110165282 [GRCh38]
Chr11:110036007 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.2590A>G (p.Met864Val) single nucleotide variant Inborn genetic diseases [RCV002734109] Chr11:110165675 [GRCh38]
Chr11:110036400 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.1417A>G (p.Ser473Gly) single nucleotide variant Inborn genetic diseases [RCV002849264] Chr11:110164502 [GRCh38]
Chr11:110035227 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.245A>G (p.Glu82Gly) single nucleotide variant Inborn genetic diseases [RCV002884655] Chr11:110136886 [GRCh38]
Chr11:110007611 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.1564G>A (p.Val522Ile) single nucleotide variant Inborn genetic diseases [RCV002872844] Chr11:110164649 [GRCh38]
Chr11:110035374 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.1756G>A (p.Asp586Asn) single nucleotide variant Inborn genetic diseases [RCV002916726] Chr11:110164841 [GRCh38]
Chr11:110035566 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.1937G>A (p.Arg646Gln) single nucleotide variant Inborn genetic diseases [RCV002892602] Chr11:110165022 [GRCh38]
Chr11:110035747 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.788A>C (p.Glu263Ala) single nucleotide variant Inborn genetic diseases [RCV002893574] Chr11:110152933 [GRCh38]
Chr11:110023658 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.1006G>A (p.Asp336Asn) single nucleotide variant Inborn genetic diseases [RCV002893606] Chr11:110159348 [GRCh38]
Chr11:110030073 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.445T>A (p.Ser149Thr) single nucleotide variant Inborn genetic diseases [RCV002699425] Chr11:110137086 [GRCh38]
Chr11:110007811 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.13G>C (p.Gly5Arg) single nucleotide variant Inborn genetic diseases [RCV002956825] Chr11:110093424 [GRCh38]
Chr11:109964150 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.479G>A (p.Arg160Gln) single nucleotide variant Inborn genetic diseases [RCV002763794] Chr11:110137120 [GRCh38]
Chr11:110007845 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.83G>A (p.Arg28His) single nucleotide variant Inborn genetic diseases [RCV002648373] Chr11:110136724 [GRCh38]
Chr11:110007449 [GRCh37]
Chr11:11q22.3
likely benign
NM_033390.2(ZC3H12C):c.1622G>A (p.Gly541Asp) single nucleotide variant Inborn genetic diseases [RCV002896263] Chr11:110164707 [GRCh38]
Chr11:110035432 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.82C>T (p.Arg28Cys) single nucleotide variant Inborn genetic diseases [RCV002657621] Chr11:110136723 [GRCh38]
Chr11:110007448 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.274G>A (p.Glu92Lys) single nucleotide variant Inborn genetic diseases [RCV003282070] Chr11:110136915 [GRCh38]
Chr11:110007640 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.382C>T (p.Pro128Ser) single nucleotide variant Inborn genetic diseases [RCV003343216] Chr11:110137023 [GRCh38]
Chr11:110007748 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.1766A>G (p.Tyr589Cys) single nucleotide variant Inborn genetic diseases [RCV003364123] Chr11:110164851 [GRCh38]
Chr11:110035576 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.387C>G (p.His129Gln) single nucleotide variant Inborn genetic diseases [RCV003369428] Chr11:110137028 [GRCh38]
Chr11:110007753 [GRCh37]
Chr11:11q22.3
uncertain significance
NM_033390.2(ZC3H12C):c.119A>G (p.His40Arg) single nucleotide variant Inborn genetic diseases [RCV003378289] Chr11:110136760 [GRCh38]
Chr11:110007485 [GRCh37]
Chr11:11q22.3
uncertain significance
Single allele duplication not provided [RCV003448710] Chr11:102134973..134945611 [GRCh37]
Chr11:11q22.2-25
pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3887
Count of miRNA genes:942
Interacting mature miRNAs:1123
Transcripts:ENST00000278590, ENST00000453089, ENST00000528673
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-34524  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711110,042,282 - 110,042,407UniSTSGRCh37
Build 3611109,547,492 - 109,547,617RGDNCBI36
Celera11107,195,748 - 107,195,873RGD
Cytogenetic Map11q22.3UniSTS
HuRef11105,966,691 - 105,966,816UniSTS
TNG Radiation Hybrid Map1150339.0UniSTS
Stanford-G3 RH Map114853.0UniSTS
GeneMap99-GB4 RH Map11367.53UniSTS
Whitehead-RH Map11502.9UniSTS
NCBI RH Map111004.0UniSTS
GeneMap99-G3 RH Map114853.0UniSTS
STS-D59827  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711110,042,159 - 110,042,282UniSTSGRCh37
Build 3611109,547,369 - 109,547,492RGDNCBI36
Celera11107,195,625 - 107,195,748RGD
Cytogenetic Map11q22.3UniSTS
HuRef11105,966,568 - 105,966,691UniSTS
GeneMap99-GB4 RH Map11369.44UniSTS
D11S1865  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711109,999,201 - 109,999,338UniSTSGRCh37
Build 3611109,504,411 - 109,504,548RGDNCBI36
Celera11107,152,740 - 107,152,877RGD
Cytogenetic Map11q22.3UniSTS
HuRef11105,923,605 - 105,923,742UniSTS
D11S3389  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711110,024,408 - 110,024,544UniSTSGRCh37
Build 3611109,529,618 - 109,529,754RGDNCBI36
Celera11107,177,923 - 107,178,059RGD
Cytogenetic Map11q22.3UniSTS
HuRef11105,948,867 - 105,949,003UniSTS
SHGC-146834  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711109,996,335 - 109,996,534UniSTSGRCh37
Build 3611109,501,545 - 109,501,744RGDNCBI36
Celera11107,149,873 - 107,150,072RGD
Cytogenetic Map11q22.3UniSTS
HuRef11105,920,737 - 105,920,936UniSTS
TNG Radiation Hybrid Map1150302.0UniSTS
D11S4676  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711110,033,554 - 110,033,666UniSTSGRCh37
Build 3611109,538,764 - 109,538,876RGDNCBI36
Celera11107,187,021 - 107,187,133RGD
Cytogenetic Map11q22.3UniSTS
HuRef11105,957,968 - 105,958,080UniSTS
TNG Radiation Hybrid Map1150343.0UniSTS
Stanford-G3 RH Map114844.0UniSTS
NCBI RH Map111003.5UniSTS
D11S4469  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711110,040,298 - 110,040,362UniSTSGRCh37
Build 3611109,545,508 - 109,545,572RGDNCBI36
Celera11107,193,764 - 107,193,828RGD
Cytogenetic Map11q22.3UniSTS
HuRef11105,964,707 - 105,964,771UniSTS
RH66754  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711110,041,113 - 110,041,284UniSTSGRCh37
Build 3611109,546,323 - 109,546,494RGDNCBI36
Celera11107,194,579 - 107,194,750RGD
Cytogenetic Map11q22.3UniSTS
HuRef11105,965,522 - 105,965,693UniSTS
GeneMap99-GB4 RH Map11367.42UniSTS
NCBI RH Map111004.0UniSTS
RH47345  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711110,042,252 - 110,042,403UniSTSGRCh37
Build 3611109,547,462 - 109,547,613RGDNCBI36
Celera11107,195,718 - 107,195,869RGD
Cytogenetic Map11q22.3UniSTS
HuRef11105,966,661 - 105,966,812UniSTS
GeneMap99-GB4 RH Map11369.24UniSTS
NCBI RH Map111004.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 96 17 129 7 411 12 858 252 626 43 108 282 3 17 748
Low 2306 2202 1590 609 637 446 3497 1919 3086 372 1329 1325 168 1187 2040 4
Below cutoff 20 752 7 6 796 6 24 14 4 16 2 2 1

Sequence


RefSeq Acc Id: ENST00000278590   ⟹   ENSP00000278590
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11110,093,392 - 110,171,841 (+)Ensembl
RefSeq Acc Id: ENST00000453089   ⟹   ENSP00000413094
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11110,135,854 - 110,171,839 (+)Ensembl
RefSeq Acc Id: ENST00000528673   ⟹   ENSP00000431821
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11110,131,004 - 110,165,934 (+)Ensembl
RefSeq Acc Id: NM_001411037   ⟹   NP_001397966
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811110,131,000 - 110,171,841 (+)NCBI
T2T-CHM13v2.011110,140,890 - 110,181,661 (+)NCBI
RefSeq Acc Id: NM_033390   ⟹   NP_203748
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811110,093,392 - 110,171,841 (+)NCBI
GRCh3711109,963,673 - 110,042,566 (+)NCBI
Build 3611109,469,297 - 109,547,776 (+)NCBI Archive
Celera11107,117,954 - 107,196,032 (+)RGD
HuRef11105,888,503 - 105,966,975 (+)ENTREZGENE
CHM1_111109,847,682 - 109,925,765 (+)NCBI
T2T-CHM13v2.011110,103,649 - 110,181,661 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001397966 (Get FASTA)   NCBI Sequence Viewer  
  NP_203748 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB21817 (Get FASTA)   NCBI Sequence Viewer  
  BAG58377 (Get FASTA)   NCBI Sequence Viewer  
  BAG61159 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000278590
  ENSP00000278590.3
  ENSP00000413094.2
  ENSP00000431821
  ENSP00000431821.1
GenBank Protein Q9C0D7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_203748   ⟸   NM_033390
- Peptide Label: isoform 1
- UniProtKB: B4DI65 (UniProtKB/Swiss-Prot),   B4DR47 (UniProtKB/Swiss-Prot),   Q9C0D7 (UniProtKB/Swiss-Prot),   E9PP00 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000413094   ⟸   ENST00000453089
RefSeq Acc Id: ENSP00000431821   ⟸   ENST00000528673
RefSeq Acc Id: ENSP00000278590   ⟸   ENST00000278590
RefSeq Acc Id: NP_001397966   ⟸   NM_001411037
- Peptide Label: isoform 2
- UniProtKB: E9PP00 (UniProtKB/TrEMBL)
Protein Domains
C3H1-type   RNase NYN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9C0D7-F1-model_v2 AlphaFold Q9C0D7 1-883 view protein structure

Promoters
RGD ID:6789593
Promoter ID:HG_KWN:14132
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   K562,   Lymphoblastoid
Transcripts:NM_033390
Position:
Human AssemblyChrPosition (strand)Source
Build 3611109,468,636 - 109,469,767 (+)MPROMDB
RGD ID:6789595
Promoter ID:HG_KWN:14133
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:UC001PKQ.2,   UC001PKR.2
Position:
Human AssemblyChrPosition (strand)Source
Build 3611109,512,771 - 109,513,271 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:29362 AgrOrtholog
COSMIC ZC3H12C COSMIC
Ensembl Genes ENSG00000149289 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000278590 ENTREZGENE
  ENST00000278590.8 UniProtKB/Swiss-Prot
  ENST00000453089.2 UniProtKB/TrEMBL
  ENST00000528673 ENTREZGENE
  ENST00000528673.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.11980 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000149289 GTEx
HGNC ID HGNC:29362 ENTREZGENE
Human Proteome Map ZC3H12C Human Proteome Map
InterPro Rege-1_UBA-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Regnase_1/ZC3H12_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNase_Zc3h12_NYN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:85463 UniProtKB/Swiss-Prot
NCBI Gene 85463 ENTREZGENE
OMIM 615001 OMIM
PANTHER N4BP1-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIBONUCLEASE ZC3H12C-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Regnase_1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNase_Zc3h12a UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA128394739 PharmGKB
PROSITE ZF_C3H1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B4DI65 ENTREZGENE
  B4DR47 ENTREZGENE
  E9PP00 ENTREZGENE, UniProtKB/TrEMBL
  Q9C0D7 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B4DI65 UniProtKB/Swiss-Prot
  B4DR47 UniProtKB/Swiss-Prot