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Gene: PLD6 (phospholipase D family member 6) Homo sapiens
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Symbol: PLD6
Name: phospholipase D family member 6
RGD ID: 1602058
Description: Exhibits cardiolipin hydrolase activity and protein homodimerization activity. Involved in mitochondrial fusion and positive regulation of mitochondrial fusion. Localizes to mitochondrial outer membrane; PARTICIPATES IN mitochondria fusion pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-hydroxypropanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: choline phosphatase 6; mitochondrial cardiolipin hydrolase; mitochondrial phospholipase; mitoPLD; phosphatidylcholine-hydrolyzing phospholipase D6; phospholipase D family, member 6; phospholipase D6; PLD 6; protein zucchini homolog; ZUC
Orthologs:
Mus musculus (house mouse) : Pld6 (phospholipase D family, member 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pld6 (phospholipase D family, member 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pld6 (phospholipase D family member 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PLD6 (phospholipase D family member 6)
Canis lupus familiaris (dog) : PLD6 (phospholipase D family member 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pld6 (phospholipase D family member 6)
Sus scrofa (pig) : PLD6 (phospholipase D family member 6)
Chlorocebus sabaeus (African green monkey) : PLD6 (phospholipase D family member 6)
Heterocephalus glaber (naked mole-rat) : Pld6 (phospholipase D family member 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1717,200,995 - 17,206,333 (-)EnsemblGRCh38hg38GRCh38
GRCh381717,200,990 - 17,206,905 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371717,104,309 - 17,109,646 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361717,045,034 - 17,050,357 (-)NCBINCBI36hg18NCBI36
Celera1718,043,902 - 18,049,239 (-)NCBI
Cytogenetic Map17p11.2NCBI
HuRef1716,857,227 - 16,862,559 (-)NCBIHuRef
CHM1_11717,113,918 - 17,119,251 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on PLD6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1602058
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.