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Gene: WDR83 (WD repeat domain 83) Homo sapiens
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Symbol: WDR83
Name: WD repeat domain 83
Description: This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MAPK organizer 1; MGC4238; mitogen-activated protein kinase organizer 1; MORG1; WD repeat domain-containing protein 83
Orthologs:
Mus musculus (house mouse) : Wdr83 (WD repeat domain containing 83)  MGI  Alliance
Rattus norvegicus (Norway rat) : Wdr83 (WD repeat domain 83)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wdr83 (WD repeat domain 83)
Pan paniscus (bonobo/pygmy chimpanzee) : WDR83 (WD repeat domain 83)
Canis lupus familiaris (dog) : WDR83 (WD repeat domain 83)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wdr83 (WD repeat domain 83)
Sus scrofa (pig) : WDR83 (WD repeat domain 83)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381912,666,804 - 12,675,832 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371912,777,618 - 12,786,646 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,638,628 - 12,647,646 (+)NCBINCBI36hg18NCBI36
Celera1912,667,332 - 12,676,360 (+)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,350,706 - 12,359,681 (+)NCBIHuRef
CHM1_11912,778,123 - 12,787,151 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on WDR83
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1601942
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2019-08-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.