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Gene: HACD4 (3-hydroxyacyl-CoA dehydratase 4) Homo sapiens
Symbol: HACD4
Name: 3-hydroxyacyl-CoA dehydratase 4
Description: Exhibits 3-hydroxyacyl-CoA dehydratase activity and enzyme binding activity. Involved in fatty acid elongation and very long-chain fatty acid biosynthetic process. Localizes to the endoplasmic reticulum; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp686F01145; DKFZp686G24132; protein tyrosine phosphatase-like protein PTPLAD2; protein-tyrosine phosphatase-like A domain-containing protein 2; PTPLAD2; very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 4; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4
Mus musculus (house mouse) : Hacd4 (3-hydroxyacyl-CoA dehydratase 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hacd4 (3-hydroxyacyl-CoA dehydratase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hacd4 (3-hydroxyacyl-CoA dehydratase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : HACD4 (3-hydroxyacyl-CoA dehydratase 4)
Canis lupus familiaris (dog) : HACD4 (3-hydroxyacyl-CoA dehydratase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hacd4 (3-hydroxyacyl-CoA dehydratase 4)
Sus scrofa (pig) : HACD4 (3-hydroxyacyl-CoA dehydratase 4)
Chlorocebus sabaeus (green monkey) : HACD4 (3-hydroxyacyl-CoA dehydratase 4)
Heterocephalus glaber (naked mole-rat) : Hacd4 (3-hydroxyacyl-CoA dehydratase 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl920,999,509 - 21,031,640 (-)Ensembl
GRCh38920,999,509 - 21,031,712 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37921,003,620 - 21,031,635 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36920,996,365 - 21,021,635 (-)NCBINCBI36hg18NCBI36
Celera920,944,643 - 20,969,914 (-)NCBI
Cytogenetic Map9p21.3NCBI
HuRef920,969,219 - 20,994,493 (-)NCBIHuRef
CHM1_1921,003,401 - 21,031,454 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HACD4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1601904
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.