Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Usp49 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of USP49 mRNA] | CTD | PMID:31150632 | 1,2-dimethylhydrazine | decreases expression | ISO | Usp49 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of USP49 mRNA | CTD | PMID:22206623 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Usp49 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Usp49 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2-hydroxypropanoic acid | increases expression | EXP | | 6480464 | Lactic Acid results in increased expression of USP49 mRNA | CTD | PMID:30851411 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Usp49 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of USP49 exon | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Usp49 (Mus musculus) | 6480464 | bisphenol S affects the methylation of USP49 gene | CTD | PMID:31683443 | 6-propyl-2-thiouracil | decreases expression | ISO | Usp49 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of USP49 mRNA | CTD | PMID:24780913 and PMID:25825206 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of USP49 mRNA | CTD | PMID:21934132 | aristolochic acid A | increases expression | EXP | | 6480464 | aristolochic acid I results in increased expression of USP49 mRNA | CTD | PMID:33212167 | bisphenol A | decreases expression | ISO | Usp49 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of USP49 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Usp49 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of USP49 mRNA | CTD | PMID:33221593 | bromobenzene | increases expression | ISO | Usp49 (Rattus norvegicus) | 6480464 | bromobenzene results in increased expression of USP49 mRNA | CTD | PMID:32479839 | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of USP49 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of USP49 mRNA | CTD | PMID:35301059 | chlorpyrifos | decreases expression | ISO | Usp49 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of USP49 mRNA | CTD | PMID:37019170 | copper atom | multiple interactions | EXP | | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of USP49 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | EXP | | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of USP49 mRNA | CTD | PMID:20971185 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | increases expression | ISO | Usp49 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of USP49 mRNA | CTD | PMID:29391264 | entinostat | decreases expression | EXP | | 6480464 | entinostat results in decreased expression of USP49 mRNA | CTD | PMID:26272509 | ethyl methanesulfonate | increases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in increased expression of USP49 mRNA | CTD | PMID:23649840 | fenvalerate | increases expression | ISO | Usp49 (Rattus norvegicus) | 6480464 | fenvalerate results in increased expression of USP49 mRNA | CTD | PMID:30307764 | formaldehyde | increases expression | EXP | | 6480464 | Formaldehyde results in increased expression of USP49 mRNA | CTD | PMID:23649840 | gentamycin | increases expression | ISO | Usp49 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of USP49 mRNA | CTD | PMID:33387578 | hydralazine | multiple interactions | EXP | | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of USP49 mRNA | CTD | PMID:17183730 | hydrogen peroxide | affects expression | EXP | | 6480464 | Hydrogen Peroxide affects the expression of USP49 mRNA | CTD | PMID:21179406 | methyl methanesulfonate | increases expression | EXP | | 6480464 | Methyl Methanesulfonate results in increased expression of USP49 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of USP49 mRNA | CTD | PMID:28001369 | N-methyl-4-phenylpyridinium | increases expression | ISO | Usp49 (Rattus norvegicus) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of USP49 mRNA | CTD | PMID:28801915 | ozone | multiple interactions | ISO | Usp49 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of USP49 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of USP49 mRNA | CTD | PMID:34911549 | panobinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of USP49 mRNA | CTD | PMID:27188386 | panobinostat | decreases expression | EXP | | 6480464 | panobinostat results in decreased expression of USP49 mRNA | CTD | PMID:26272509 | paracetamol | affects expression | ISO | Usp49 (Mus musculus) | 6480464 | Acetaminophen affects the expression of USP49 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | Usp49 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of USP49 mRNA | CTD | PMID:33387578 | PCB138 | multiple interactions | ISO | Usp49 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | pentanal | decreases expression | EXP | | 6480464 | pentanal results in decreased expression of USP49 mRNA | CTD | PMID:26079696 | phenylmercury acetate | decreases expression | EXP | | 6480464 | Phenylmercuric Acetate results in decreased expression of USP49 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of USP49 mRNA | CTD | PMID:27188386 | pirinixic acid | multiple interactions | EXP | | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of USP49 mRNA | CTD | PMID:19710929 | rac-lactic acid | increases expression | EXP | | 6480464 | Lactic Acid results in increased expression of USP49 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide analog results in increased expression of USP49 mRNA | CTD | PMID:23806026 | Soman | increases expression | ISO | Usp49 (Rattus norvegicus) | 6480464 | Soman results in increased expression of USP49 mRNA | CTD | PMID:19281266 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of USP49 mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | EXP | | 6480464 | Temozolomide results in decreased expression of USP49 mRNA | CTD | PMID:31758290 | tetrachloromethane | decreases expression | ISO | Usp49 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of USP49 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | ISO | Usp49 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of USP49 mRNA] | CTD | PMID:31150632 | thimerosal | decreases expression | EXP | | 6480464 | Thimerosal results in decreased expression of USP49 mRNA | CTD | PMID:27188386 | torcetrapib | increases expression | EXP | | 6480464 | torcetrapib results in increased expression of USP49 mRNA | CTD | PMID:23228038 | trichloroethene | decreases expression | ISO | Usp49 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of USP49 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | EXP | | 6480464 | trichostatin A results in decreased expression of USP49 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | affects expression | EXP | | 6480464 | trichostatin A affects the expression of USP49 mRNA | CTD | PMID:28542535 | trichostatin A | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of USP49 mRNA | CTD | PMID:27188386 | triptonide | increases expression | ISO | Usp49 (Mus musculus) | 6480464 | triptonide results in increased expression of USP49 mRNA | CTD | PMID:33045310 | valproic acid | multiple interactions | EXP | | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of USP49 mRNA more ... | CTD | PMID:17183730 and PMID:27188386 | valproic acid | affects expression | ISO | Usp49 (Mus musculus) | 6480464 | Valproic Acid affects the expression of USP49 mRNA | CTD | PMID:17292431 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of USP49 mRNA | CTD | PMID:23179753 more ... | vorinostat | decreases expression | EXP | | 6480464 | vorinostat results in decreased expression of USP49 mRNA | CTD | PMID:26272509 and PMID:27188386 | |