TAF1D (TATA-box binding protein associated factor, RNA polymerase I subunit D) - Rat Genome Database
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Gene: TAF1D (TATA-box binding protein associated factor, RNA polymerase I subunit D) Homo sapiens
Analyze
Symbol: TAF1D
Name: TATA-box binding protein associated factor, RNA polymerase I subunit D
RGD ID: 1601854
Description: Exhibits identical protein binding activity. Predicted to be involved in positive regulation of gene expression, epigenetic and transcription by RNA polymerase I. Localizes to cytosol; microtubule cytoskeleton; and nuclear lumen.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ23363; FLJ32621; FLJ46181; JOSD3; Josephin domain containing 3; MGC5306; RAFI41; RNA polymerase I-specific TBP-associated factor 41 kDa; TAF(I)41; TAFI41; TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa; TATA box binding protein associated factor 1D; TATA box-binding protein-associated factor 1D; TATA box-binding protein-associated factor RNA polymerase I subunit D; TATA-box binding protein associated factor, RNA polymerase I, D; TBP-associated factor 1D; transcription initiation factor SL1/TIF-IB subunit D
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1193,729,948 - 93,784,391 (-)EnsemblGRCh38hg38GRCh38
GRCh381193,730,194 - 93,741,495 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371193,463,368 - 93,474,703 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361193,108,743 - 93,114,310 (-)NCBINCBI36hg18NCBI36
Celera1190,760,547 - 90,766,156 (-)NCBI
Cytogenetic Map11q21NCBI
HuRef1189,546,328 - 89,551,937 (-)NCBIHuRef
CHM1_11193,352,108 - 93,357,722 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin M1  (EXP)
all-trans-retinoic acid  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbamazepine  (EXP)
carbon nanotube  (ISO)
chloroprene  (ISO)
chromium(6+)  (EXP,ISO)
cisplatin  (EXP)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (EXP)
DDT  (EXP)
diarsenic trioxide  (EXP)
dibutyl phthalate  (ISO)
dicrotophos  (EXP)
dorsomorphin  (EXP)
fluoranthene  (ISO)
glafenine  (ISO)
glyphosate  (ISO)
leflunomide  (EXP,ISO)
methapyrilene  (ISO)
methoxyacetic acid  (ISO)
methyl methanesulfonate  (EXP)
methylmercury chloride  (EXP,ISO)
methylparaben  (EXP)
Monobutylphthalate  (ISO)
oxaliplatin  (ISO)
paracetamol  (ISO)
phenobarbital  (EXP)
pirinixic acid  (ISO)
potassium chromate  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
rac-lactic acid  (EXP)
SB 431542  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP,ISO)
sodium fluoride  (ISO)
succimer  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
topotecan  (ISO)
trichostatin A  (EXP)
tungsten  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vincristine  (EXP)
vitamin E  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:15489334   PMID:15520167   PMID:16169070   PMID:17207965   PMID:17318177   PMID:19615732   PMID:21386990   PMID:21873635   PMID:21900206   PMID:25416956  
PMID:26186194   PMID:26496610   PMID:26760575   PMID:28514442   PMID:29150431   PMID:32296183  


Genomics

Comparative Map Data
TAF1D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1193,729,948 - 93,784,391 (-)EnsemblGRCh38hg38GRCh38
GRCh381193,730,194 - 93,741,495 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371193,463,368 - 93,474,703 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361193,108,743 - 93,114,310 (-)NCBINCBI36hg18NCBI36
Celera1190,760,547 - 90,766,156 (-)NCBI
Cytogenetic Map11q21NCBI
HuRef1189,546,328 - 89,551,937 (-)NCBIHuRef
CHM1_11193,352,108 - 93,357,722 (-)NCBICHM1_1
Taf1d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39915,217,485 - 15,228,293 (+)NCBI
GRCm38915,305,953 - 15,316,997 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl915,306,214 - 15,316,991 (+)EnsemblGRCm38mm10GRCm38
MGSCv37915,110,658 - 15,121,441 (+)NCBIGRCm37mm9NCBIm37
MGSCv36915,056,653 - 15,067,390 (+)NCBImm8
Celera912,585,532 - 12,595,986 (+)NCBICelera
Cytogenetic Map9A2NCBI
Taf1d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0813,861,242 - 13,871,508 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl813,861,459 - 13,871,354 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0813,800,779 - 13,811,374 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4812,107,144 - 12,117,177 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1812,108,474 - 12,117,177 (+)NCBI
Celera813,614,324 - 13,624,354 (+)NCBICelera
Cytogenetic Map8q12NCBI
Taf1d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955414799,138 - 803,005 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955414799,124 - 806,242 (+)NCBIChiLan1.0ChiLan1.0
TAF1D
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11192,241,125 - 92,250,412 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1192,241,126 - 92,250,416 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01188,752,779 - 88,763,136 (-)NCBIMhudiblu_PPA_v0panPan3
TAF1D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1217,013,383 - 7,023,497 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Taf1d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366741,044,519 - 1,053,744 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAF1D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl926,147,149 - 26,167,290 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1926,154,910 - 26,167,282 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2929,682,286 - 29,689,261 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TAF1D
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl184,988,280 - 84,994,290 (-)Ensembl
ChlSab1.1184,982,364 - 84,993,601 (-)NCBI
Taf1d
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473538,397,922 - 38,407,255 (-)NCBI

Position Markers
D11S4346  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371193,469,159 - 93,469,308UniSTSGRCh37
Build 361193,108,807 - 93,108,956RGDNCBI36
Celera1190,760,611 - 90,760,760RGD
Cytogenetic Map11q21UniSTS
HuRef1189,546,392 - 89,546,541UniSTS
Stanford-G3 RH Map114080.0UniSTS
NCBI RH Map11785.0UniSTS
GeneMap99-G3 RH Map114080.0UniSTS
RH35  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371193,463,414 - 93,463,566UniSTSGRCh37
Build 361193,103,062 - 93,103,214RGDNCBI36
Celera1190,754,866 - 90,755,018RGD
Cytogenetic Map11q21UniSTS
HuRef1189,540,645 - 89,540,797UniSTS
SHGC-132183  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371193,469,219 - 93,469,320UniSTSGRCh37
Build 361193,108,867 - 93,108,968RGDNCBI36
Celera1190,760,671 - 90,760,772RGD
Cytogenetic Map11q21UniSTS
HuRef1189,546,452 - 89,546,553UniSTS
TNG Radiation Hybrid Map1143214.0UniSTS
D11S4684  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371193,466,267 - 93,466,435UniSTSGRCh37
Build 361193,105,915 - 93,106,083RGDNCBI36
Celera1190,757,719 - 90,757,887RGD
Cytogenetic Map11q21UniSTS
HuRef1189,543,500 - 89,543,668UniSTS
TNG Radiation Hybrid Map1143202.0UniSTS
Stanford-G3 RH Map114075.0UniSTS
NCBI RH Map11785.0UniSTS
GeneMap99-G3 RH Map114075.0UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2561
Count of miRNA genes:887
Interacting mature miRNAs:1046
Transcripts:ENST00000323981, ENST00000393259, ENST00000448108, ENST00000525928, ENST00000526015, ENST00000527068, ENST00000527169, ENST00000527690, ENST00000528734, ENST00000529435, ENST00000529508, ENST00000529794, ENST00000529900, ENST00000530089, ENST00000530769, ENST00000532235, ENST00000532455, ENST00000533794, ENST00000534079, ENST00000534770, ENST00000540232, ENST00000546088
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2416 1986 1584 502 1447 345 4179 1675 3281 318 1438 1603 174 1 1203 2623 6 2
Low 23 1004 142 122 503 120 178 522 453 101 22 10 1 1 165
Below cutoff 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_024116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA449756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF086435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF275800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK027016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK057183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK128061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP001273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ774057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR457369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DW450227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HF584215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT585242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000323981   ⟹   ENSP00000314971
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,729,948 - 93,741,494 (-)Ensembl
RefSeq Acc Id: ENST00000393259   ⟹   ENSP00000376944
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,730,281 - 93,736,741 (-)Ensembl
RefSeq Acc Id: ENST00000448108   ⟹   ENSP00000410409
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,735,567 - 93,741,495 (-)Ensembl
RefSeq Acc Id: ENST00000525928
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,730,283 - 93,734,661 (-)Ensembl
RefSeq Acc Id: ENST00000526015   ⟹   ENSP00000435087
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,730,194 - 93,741,493 (-)Ensembl
RefSeq Acc Id: ENST00000527068
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,733,305 - 93,738,292 (-)Ensembl
RefSeq Acc Id: ENST00000527169   ⟹   ENSP00000433119
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,731,146 - 93,741,479 (-)Ensembl
RefSeq Acc Id: ENST00000527690   ⟹   ENSP00000432852
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,739,281 - 93,784,391 (-)Ensembl
RefSeq Acc Id: ENST00000528734
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,735,915 - 93,736,967 (-)Ensembl
RefSeq Acc Id: ENST00000529435
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,730,354 - 93,735,238 (-)Ensembl
RefSeq Acc Id: ENST00000529508
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,738,967 - 93,741,494 (-)Ensembl
RefSeq Acc Id: ENST00000529794
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,732,977 - 93,736,806 (-)Ensembl
RefSeq Acc Id: ENST00000529900
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,730,667 - 93,732,268 (-)Ensembl
RefSeq Acc Id: ENST00000530089
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,731,161 - 93,736,157 (-)Ensembl
RefSeq Acc Id: ENST00000530769
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,730,282 - 93,735,848 (-)Ensembl
RefSeq Acc Id: ENST00000532235
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,737,156 - 93,741,476 (-)Ensembl
RefSeq Acc Id: ENST00000532455   ⟹   ENSP00000431570
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,738,109 - 93,741,495 (-)Ensembl
RefSeq Acc Id: ENST00000533794   ⟹   ENSP00000446311
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,732,800 - 93,736,239 (-)Ensembl
RefSeq Acc Id: ENST00000534079
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,730,200 - 93,732,501 (-)Ensembl
RefSeq Acc Id: ENST00000534770   ⟹   ENSP00000435304
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,737,089 - 93,741,480 (-)Ensembl
RefSeq Acc Id: ENST00000540232   ⟹   ENSP00000441633
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,730,682 - 93,736,289 (-)Ensembl
RefSeq Acc Id: ENST00000546088
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1193,730,272 - 93,736,175 (-)Ensembl
RefSeq Acc Id: NM_024116   ⟹   NP_077021
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381193,735,567 - 93,741,495 (-)NCBI
GRCh371193,463,368 - 93,474,703 (-)NCBI
Build 361193,108,743 - 93,114,310 (-)NCBI Archive
Celera1190,760,547 - 90,766,156 (-)RGD
HuRef1189,546,328 - 89,551,937 (-)ENTREZGENE
CHM1_11193,352,108 - 93,357,722 (-)NCBI
Sequence:
RefSeq Acc Id: NR_146090
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381193,730,194 - 93,741,495 (-)NCBI
Sequence:
RefSeq Acc Id: NR_146091
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381193,730,194 - 93,741,495 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_077021   ⟸   NM_024116
- UniProtKB: Q9H5J8 (UniProtKB/Swiss-Prot),   A0A024R3A9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000431570   ⟸   ENST00000532455
RefSeq Acc Id: ENSP00000446311   ⟸   ENST00000533794
RefSeq Acc Id: ENSP00000314971   ⟸   ENST00000323981
RefSeq Acc Id: ENSP00000435304   ⟸   ENST00000534770
RefSeq Acc Id: ENSP00000376944   ⟸   ENST00000393259
RefSeq Acc Id: ENSP00000435087   ⟸   ENST00000526015
RefSeq Acc Id: ENSP00000410409   ⟸   ENST00000448108
RefSeq Acc Id: ENSP00000433119   ⟸   ENST00000527169
RefSeq Acc Id: ENSP00000432852   ⟸   ENST00000527690
RefSeq Acc Id: ENSP00000441633   ⟸   ENST00000540232

Promoters
RGD ID:6788894
Promoter ID:HG_KWN:13959
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000408243,   UC001PEC.2
Position:
Human AssemblyChrPosition (strand)Source
Build 361193,105,181 - 93,109,627 (-)MPROMDB
RGD ID:6814503
Promoter ID:HG_XEF:1563
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   Jurkat,   Lymphoblastoid
Transcripts:NM_001037586,   NM_029248
Position:
Human AssemblyChrPosition (strand)Source
Build 361193,110,821 - 93,112,207 (-)MPROMDB
RGD ID:6789422
Promoter ID:HG_KWN:13960
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000323981,   NM_014039,   UC001PDZ.2,   UC001PEA.1,   UC001PED.1,   UC001PEE.1,   UC001PEG.1,   UC001PEH.1,   UC001PEI.1,   UC009YWI.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361193,113,156 - 93,114,332 (-)MPROMDB
RGD ID:6850604
Promoter ID:EP73096
Type:single initiation site
Name:HS_MGC5306
Description:Hypothetical protein MGC5306.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 361193,114,308 - 93,114,368EPD
RGD ID:7221813
Promoter ID:EPDNEW_H16652
Type:multiple initiation site
Name:TAF1D_2
Description:TATA-box binding protein associated factor, RNA polymerase Isubunit D
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16653  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381193,740,432 - 93,740,492EPDNEW
RGD ID:7221815
Promoter ID:EPDNEW_H16653
Type:initiation region
Name:TAF1D_1
Description:TATA-box binding protein associated factor, RNA polymerase Isubunit D
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16652  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381193,741,494 - 93,741,554EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q14.1-22.3(chr11:78232836-106779420)x1 copy number loss See cases [RCV000052710] Chr11:78232836..106779420 [GRCh38]
Chr11:77943882..106650146 [GRCh37]
Chr11:77621530..106155356 [NCBI36]
Chr11:11q14.1-22.3
pathogenic
GRCh38/hg38 11q14.1-22.2(chr11:85242847-102920097)x1 copy number loss See cases [RCV000052711] Chr11:85242847..102920097 [GRCh38]
Chr11:84953891..102738968 [GRCh37]
Chr11:84631539..102296037 [NCBI36]
Chr11:11q14.1-22.2
pathogenic
NM_024116.3(TAF1D):c.326C>T (p.Pro109Leu) single nucleotide variant Malignant melanoma [RCV000069754] Chr11:93738242 [GRCh38]
Chr11:93471408 [GRCh37]
Chr11:93111056 [NCBI36]
Chr11:11q21
not provided
GRCh38/hg38 11q13.5-22.1(chr11:75941754-98357960)x1 copy number loss See cases [RCV000133838] Chr11:75941754..98357960 [GRCh38]
Chr11:75652798..98228688 [GRCh37]
Chr11:75330446..97733898 [NCBI36]
Chr11:11q13.5-22.1
pathogenic
GRCh38/hg38 11q14.3-22.3(chr11:91086659-109595582)x1 copy number loss See cases [RCV000138038] Chr11:91086659..109595582 [GRCh38]
Chr11:90819827..109466308 [GRCh37]
Chr11:90459475..108971518 [NCBI36]
Chr11:11q14.3-22.3
pathogenic
GRCh37/hg19 11q14.1-21(chr11:80318996-96116221)x1 copy number loss See cases [RCV000446395] Chr11:80318996..96116221 [GRCh37]
Chr11:11q14.1-21
pathogenic
GRCh37/hg19 11q14.1-21(chr11:84924674-93574799)x1 copy number loss See cases [RCV000448436] Chr11:84924674..93574799 [GRCh37]
Chr11:11q14.1-21
likely pathogenic
GRCh37/hg19 11q14.2-22.3(chr11:88152458-109414650)x1 copy number loss See cases [RCV000510457] Chr11:88152458..109414650 [GRCh37]
Chr11:11q14.2-22.3
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11q13.4-23.3(chr11:71588805-116680918)x3 copy number gain not provided [RCV000683374] Chr11:71588805..116680918 [GRCh37]
Chr11:11q13.4-23.3
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11q14.1-23.2(chr11:80053454-113316236)x1 copy number loss not provided [RCV000737595] Chr11:80053454..113316236 [GRCh37]
Chr11:11q14.1-23.2
pathogenic
GRCh37/hg19 11q14.1-21(chr11:83179196-94716998)x3 copy number gain not provided [RCV000750120] Chr11:83179196..94716998 [GRCh37]
Chr11:11q14.1-21
pathogenic
NM_033395.2(CEP295):c.7768-10C>T single nucleotide variant not provided [RCV000881636] Chr11:93730221 [GRCh38]
Chr11:93463387 [GRCh37]
Chr11:11q21
benign
GRCh37/hg19 11q21(chr11:93297444-94041273)x3 copy number gain not provided [RCV001006434] Chr11:93297444..94041273 [GRCh37]
Chr11:11q21
uncertain significance
GRCh37/hg19 11q14.3-21(chr11:92615227-93592229)x3 copy number gain not provided [RCV001260144] Chr11:92615227..93592229 [GRCh37]
Chr11:11q14.3-21
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:28759 AgrOrtholog
COSMIC TAF1D COSMIC
Ensembl Genes ENSG00000166012 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000314971 UniProtKB/Swiss-Prot
  ENSP00000376944 UniProtKB/TrEMBL
  ENSP00000410409 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000431570 UniProtKB/TrEMBL
  ENSP00000432852 UniProtKB/TrEMBL
  ENSP00000433119 UniProtKB/TrEMBL
  ENSP00000435087 UniProtKB/Swiss-Prot
  ENSP00000435304 UniProtKB/TrEMBL
  ENSP00000441633 UniProtKB/TrEMBL
  ENSP00000446311 UniProtKB/TrEMBL
Ensembl Transcript ENST00000323981 UniProtKB/Swiss-Prot
  ENST00000393259 UniProtKB/TrEMBL
  ENST00000448108 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000526015 UniProtKB/Swiss-Prot
  ENST00000527169 UniProtKB/TrEMBL
  ENST00000527690 UniProtKB/TrEMBL
  ENST00000532455 UniProtKB/TrEMBL
  ENST00000533794 UniProtKB/TrEMBL
  ENST00000534770 UniProtKB/TrEMBL
  ENST00000540232 UniProtKB/TrEMBL
GTEx ENSG00000166012 GTEx
HGNC ID HGNC:28759 ENTREZGENE
Human Proteome Map TAF1D Human Proteome Map
InterPro TAF1D UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:79101 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 79101 ENTREZGENE
OMIM 612823 OMIM
PANTHER PTHR14562 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TAF1D UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA164726421 PharmGKB
UniGene Hs.355750 ENTREZGENE
  Hs.732267 ENTREZGENE
UniProt A0A024R3A9 ENTREZGENE, UniProtKB/TrEMBL
  A0A1D5RMT6_HUMAN UniProtKB/TrEMBL
  E9PKU8_HUMAN UniProtKB/TrEMBL
  E9PM59_HUMAN UniProtKB/TrEMBL
  H0Y3L3_HUMAN UniProtKB/TrEMBL
  H0YCH2_HUMAN UniProtKB/TrEMBL
  H0YG36_HUMAN UniProtKB/TrEMBL
  H0YH71_HUMAN UniProtKB/TrEMBL
  L8ECK2_HUMAN UniProtKB/TrEMBL
  Q9H5J8 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q6I9Y6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-07 TAF1D  TATA-box binding protein associated factor, RNA polymerase I subunit D    TATA-box binding protein associated factor, RNA polymerase I, D  Symbol and/or name change 5135510 APPROVED
2015-11-24 TAF1D  TATA-box binding protein associated factor, RNA polymerase I, D    TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa  Symbol and/or name change 5135510 APPROVED
2011-09-01 TAF1D  TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa  TAF1D  TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa  Symbol and/or name change 5135510 APPROVED