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Gene: WWC3 (WWC family member 3) Homo sapiens
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Symbol: WWC3
Name: WWC family member 3
Description: Exhibits kinase binding activity and molecular adaptor activity. Involved in negative regulation of hippo signaling; negative regulation of organ growth; and negative regulation of transcription by RNA polymerase II. Localizes to the cytosol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BM042; KIAA1280
Orthologs:
Rattus norvegicus (Norway rat) : Wwc3 (WWC family member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wwc3 (WWC family member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : WWC3 (WWC family member 3)
Canis lupus familiaris (dog) : WWC3 (WWC family member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wwc3 (WWC family member 3)
Sus scrofa (pig) : WWC3 (WWC family member 3)
Chlorocebus sabaeus (African green monkey) : WWC3 (WWC family member 3)
Heterocephalus glaber (naked mole-rat) : Wwc3 (WWC family member 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX10,015,562 - 10,144,478 (+)Ensembl
GRCh38X10,015,254 - 10,144,474 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X9,983,795 - 10,112,518 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X9,943,795 - 10,072,518 (+)NCBINCBI36hg18NCBI36
CeleraX14,155,064 - 14,283,798 (+)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX7,861,614 - 7,942,180 (+)NCBIHuRef
CHM1_1X10,014,187 - 10,142,938 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on WWC3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1601752
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.