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Gene: Nkx6-3 (NK6 homeobox 3) Rattus norvegicus
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Symbol: Nkx6-3
Name: NK6 homeobox 3
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including glandular epithelial cell differentiation; negative regulation of epithelial cell differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Orthologous to human NKX6-3 (NK6 homeobox 3); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: homeobox protein Nkx-6.3; LOC685102; similar to NK6 transcription factor related, locus 2
Orthologs:
Homo sapiens (human) : NKX6-3 (NK6 homeobox 3)  HGNC  Alliance
Mus musculus (house mouse) : Nkx6-3 (NK6 homeobox 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nkx6-3 (NK6 homeobox 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NKX6-3 (NK6 homeobox 3)
Canis lupus familiaris (dog) : NKX6-3 (NK6 homeobox 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nkx6-3 (NK6 homeobox 3)
Sus scrofa (pig) : NKX6-3 (NK6 homeobox 3)
Chlorocebus sabaeus (African green monkey) : NKX6-3 (NK6 homeobox 3)
Heterocephalus glaber (naked mole-rat) : Nkx6-3 (NK6 homeobox 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01673,665,269 - 73,670,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1673,665,269 - 73,670,482 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01673,297,719 - 73,302,932 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41673,325,677 - 73,330,890 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1666,760,348 - 66,765,561 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Nkx6-3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1597780
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.