Gene: Lin28b (lin-28 homolog B) Rattus norvegicus
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Symbol: Lin28b
Name: lin-28 homolog B
Description: ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN miRNA catabolic process (ortholog); pre-miRNA processing (ortholog); RNA 3'-end processing (ortholog); ASSOCIATED WITH Cell Transformation, Neoplastic (ortholog); disease of cellular proliferation (ortholog); neuroblastoma (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH atrazine; bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)
AGR Description: Predicted to have RNA binding activity; predicted to be involved in RNA 3'-end processing, miRNA catabolic process, and pre-miRNA processing; predicted to localize to the cytosol and nucleolus; orthologous to human LIN28B (lin-28 homolog B).
Merged Description: Predicted to have RNA binding activity; predicted to be involved in RNA 3'-end processing, miRNA catabolic process, and pre-miRNA processing; predicted to localize to the cytosol and nucleolus; orthologous to human LIN28B (lin-28 homolog B); INTERACTS WITH atrazine; bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: lin-28 homolog B (C. elegans); LOC683611; LOC689054; similar to lin-28 homolog b
Orthologs:
Homo sapiens (human) : LIN28B (lin-28 homolog B)  HGNC  Alliance
Mus musculus (house mouse) : Lin28b (lin-28 homolog B (C. elegans))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lin28b (lin-28 homolog B)
Pan paniscus (bonobo/pygmy chimpanzee) : LIN28B (lin-28 homolog B)
Canis lupus familiaris (dog) : LIN28B (lin-28 homolog B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lin28b (lin-28 homolog B)
Sus scrofa (pig) : LIN28B (lin-28 homolog B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02050,482,536 - 50,580,273 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02052,094,397 - 52,182,964 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42049,685,524 - 49,765,967 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2051,065,112 - 51,157,124 (+)NCBICelera
Cytogenetic Map20q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lin28b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1597432
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.