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Gene: E4f1 (E4F transcription factor 1) Rattus norvegicus
Symbol: E4f1
Name: E4F transcription factor 1
Description: Predicted to have cAMP response element binding activity. Predicted to be involved in several processes, including DNA replication; negative regulation of transcription by RNA polymerase II; and regulation of mitotic cell cycle, embryonic. Predicted to localize to the nucleoplasm and spindle. Orthologous to human E4F1 (E4F transcription factor 1); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH bisphenol A; endosulfan; 1-Hydroxypyrene (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: deoxyribonuclease 1-like 2; Dnase1l2; LOC287114; LOC681359; similar to p120E4F; transcription factor E4F1
Homo sapiens (human) : E4F1 (E4F transcription factor 1)  HGNC  Alliance
Mus musculus (house mouse) : E4f1 (E4F transcription factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : E4f1 (E4F transcription factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : E4F1 (E4F transcription factor 1)
Canis lupus familiaris (dog) : E4F1 (E4F transcription factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : E4f1 (E4F transcription factor 1)
Sus scrofa (pig) : E4F1 (E4F transcription factor 1)
Chlorocebus sabaeus (African green monkey) : E4F1 (E4F transcription factor 1)
Heterocephalus glaber (naked mole-rat) : E4f1 (E4F transcription factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01013,812,335 - 13,835,847 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,815,293 - 13,826,945 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,629,321 - 13,644,753 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,701,558 - 13,713,008 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11013,698,967 - 13,713,008 (-)NCBI
Celera1013,154,954 - 13,166,469 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on E4f1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1596731
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.