Rnf133 (ring finger protein 133) - Rat Genome Database

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Gene: Rnf133 (ring finger protein 133) Rattus norvegicus
Analyze
Symbol: Rnf133
Name: ring finger protein 133
RGD ID: 1596695
Description: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein autoubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be active in Golgi apparatus; endoplasmic reticulum membrane; and late endosome. Orthologous to human RNF133 (ring finger protein 133); INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); 4,4'-sulfonyldiphenol (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E3 ubiquitin-protein ligase RNF133; LOC681395; RING-type E3 ubiquitin transferase RNF133; similar to ring finger protein 133
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8453,106,097 - 53,109,032 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl453,104,688 - 53,112,678 (-)EnsemblGRCr8
mRatBN7.2452,140,584 - 52,143,357 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl452,140,247 - 52,143,379 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx457,120,650 - 57,122,005 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0453,041,678 - 53,043,033 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0451,470,679 - 51,472,034 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0450,681,843 - 50,686,216 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0450,462,281 - 50,465,170 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4450,024,631 - 50,025,986 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera447,332,014 - 47,333,369 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:18574499  


Genomics

Comparative Map Data
Rnf133
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8453,106,097 - 53,109,032 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl453,104,688 - 53,112,678 (-)EnsemblGRCr8
mRatBN7.2452,140,584 - 52,143,357 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl452,140,247 - 52,143,379 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx457,120,650 - 57,122,005 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0453,041,678 - 53,043,033 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0451,470,679 - 51,472,034 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0450,681,843 - 50,686,216 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0450,462,281 - 50,465,170 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4450,024,631 - 50,025,986 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera447,332,014 - 47,333,369 (-)NCBICelera
Cytogenetic Map4q22NCBI
RNF133
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387122,697,735 - 122,699,117 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7122,697,735 - 122,699,117 (-)Ensemblhg38GRCh38
GRCh377122,337,789 - 122,339,171 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367122,125,002 - 122,126,444 (-)NCBIBuild 36Build 36hg18NCBI36
Build 347121,931,716 - 121,933,159NCBI
Celera7117,142,067 - 117,143,509 (-)NCBICelera
Cytogenetic Map7q31.32NCBI
HuRef7116,700,656 - 116,702,098 (-)NCBIHuRef
CHM1_17122,271,067 - 122,272,509 (-)NCBICHM1_1
T2T-CHM13v2.07124,013,735 - 124,015,117 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27121,732,467 - 121,733,909 (-)NCBI
Rnf133
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39623,648,868 - 23,650,304 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl623,648,868 - 23,650,304 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38623,648,869 - 23,650,305 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl623,648,869 - 23,650,305 (-)Ensemblmm10GRCm38
MGSCv37623,598,869 - 23,600,305 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36623,598,871 - 23,600,307 (-)NCBIMGSCv36mm8
Celera623,671,958 - 23,673,394 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
cM Map611.01NCBI
Rnf133
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554794,318,589 - 4,319,704 (-)Ensembl
ChiLan1.0NW_0049554794,318,513 - 4,319,974 (-)NCBIChiLan1.0ChiLan1.0
RNF133
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26159,568,096 - 159,572,711 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1711,578,350 - 11,582,965 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07114,707,995 - 114,709,482 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17127,391,684 - 127,393,125 (-)NCBIPanPan1.1PanPan1.1panPan2
RNF133
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11460,418,047 - 60,419,471 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1459,838,850 - 59,840,276 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01460,457,834 - 60,459,260 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11460,547,712 - 60,549,138 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01460,175,226 - 60,176,650 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01460,553,163 - 60,554,589 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rnf133
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511849,527,584 - 49,529,262 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366052,674,883 - 2,676,331 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF133
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11824,530,956 - 24,533,936 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21826,127,936 - 26,129,580 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF133
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12191,490,388 - 91,492,206 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2191,490,582 - 91,491,712 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604211,999,067 - 12,002,516 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf133
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478313,307,057 - 13,308,168 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462478313,306,762 - 13,308,226 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Rnf133
3 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)43952426474726312Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
10450825Scl78Serum cholesterol level QTL 783.70.01blood VLDL cholesterol amount (VT:0005144)blood low density lipoprotein cholesterol level (CMO:0000053)44917811657114705Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
10450821Scl77Serum cholesterol level QTL 774.10.01blood VLDL cholesterol amount (VT:0005144)blood high density lipoprotein cholesterol level (CMO:0000052)44917811657114705Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
10450818Scl76Serum cholesterol level QTL 763.60.01blood VLDL cholesterol amount (VT:0005144)blood high density lipoprotein cholesterol level (CMO:0000052)44917811657114705Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)43950527573892441Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41794699962946999Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43258419952754138Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
mesenchyme
mesoderm
musculoskeletal system
renal system
reproductive system
7 4 2 35 6 2 22 22

Sequence


Ensembl Acc Id: ENSRNOT00000115813   ⟹   ENSRNOP00000079460
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl453,104,688 - 53,110,009 (-)Ensembl
mRatBN7.2 Ensembl452,140,247 - 52,143,379 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000171415   ⟹   ENSRNOP00000100309
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl453,105,246 - 53,112,678 (-)Ensembl
RefSeq Acc Id: NM_001044278   ⟹   NP_001037743
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8453,106,206 - 53,107,561 (-)NCBI
mRatBN7.2452,140,588 - 52,141,943 (-)NCBI
Rnor_6.0450,681,949 - 50,683,304 (-)NCBI
Rnor_5.0450,462,281 - 50,465,170 (-)NCBI
RGSC_v3.4450,024,631 - 50,025,986 (-)RGD
Celera447,332,014 - 47,333,369 (-)RGD
Sequence:
RefSeq Acc Id: XM_006236144   ⟹   XP_006236206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8453,106,097 - 53,109,032 (-)NCBI
mRatBN7.2452,140,584 - 52,143,357 (-)NCBI
Rnor_6.0450,681,843 - 50,686,216 (-)NCBI
Rnor_5.0450,462,281 - 50,465,170 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001037743 (Get FASTA)   NCBI Sequence Viewer  
  XP_006236206 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79249 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000079460
  ENSRNOP00000079460.1
GenBank Protein Q6AY01 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001037743   ⟸   NM_001044278
- UniProtKB: Q6AY01 (UniProtKB/Swiss-Prot),   A6IE77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236206   ⟸   XM_006236144
- Peptide Label: isoform X1
- UniProtKB: Q6AY01 (UniProtKB/Swiss-Prot),   A6IE77 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000079460   ⟸   ENSRNOT00000115813
Ensembl Acc Id: ENSRNOP00000100309   ⟸   ENSRNOT00000171415
Protein Domains
PA   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AY01-F1-model_v2 AlphaFold Q6AY01 1-381 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1596695 AgrOrtholog
BioCyc Gene G2FUF-45495 BioCyc
Ensembl Genes ENSRNOG00000065130 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000115813 ENTREZGENE
  ENSRNOT00000115813.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot
  3.50.30.30 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7133029 IMAGE-MGC_LOAD
InterPro PA_dom_sf UniProtKB/Swiss-Prot
  PA_domain UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
KEGG Report rno:681395 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94340 IMAGE-MGC_LOAD
NCBI Gene 681395 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE ATL42 UniProtKB/Swiss-Prot
  RING FINGER PROTEIN 128 UniProtKB/Swiss-Prot
Pfam PF02225 UniProtKB/Swiss-Prot
  zf-RING_2 UniProtKB/Swiss-Prot
PhenoGen Rnf133 PhenoGen
PROSITE ZF_RING_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000065130 RatGTEx
SMART RING UniProtKB/Swiss-Prot
Superfamily-SCOP PA domain UniProtKB/Swiss-Prot
  RING/U-box UniProtKB/Swiss-Prot
UniProt A6IE77 ENTREZGENE, UniProtKB/TrEMBL
  Q6AY01 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-21 Rnf133  ring finger protein 133  LOC681395  similar to ring finger protein 133  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC681395  similar to ring finger protein 133  LOC681784  similar to ring finger protein 133  Data merged from RGD:1591621 1643240 APPROVED
2006-11-20 LOC681395  similar to ring finger protein 133      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC681784  similar to ring finger protein 133      Symbol and Name status set to provisional 70820 PROVISIONAL