Gene: Ackr4 (atypical chemokine receptor 4) Rattus norvegicus
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Symbol: Ackr4
Name: atypical chemokine receptor 4
Description: ENCODES a protein that exhibits chemokine receptor activity (ortholog); INVOLVED IN chemokine-mediated signaling pathway (inferred); G protein-coupled receptor signaling pathway (inferred); vesicle-mediated transport (inferred); ASSOCIATED WITH Spontaneous Abortion (ortholog); FOUND IN integral component of membrane (inferred); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; diuron; endosulfan
AGR Description: Predicted to have C-C chemokine binding activity and C-C chemokine receptor activity; predicted to be involved in several processes, including calcium-mediated signaling, cell chemotaxis, and immune response; predicted to localize to the external side of plasma membrane; orthologous to human ACKR4 (atypical chemokine receptor 4).
Merged Description: Predicted to have C-C chemokine binding activity and C-C chemokine receptor activity; predicted to be involved in several processes, including calcium-mediated signaling, cell chemotaxis, and immune response; predicted to localize to the external side of plasma membrane; orthologous to human ACKR4 (atypical chemokine receptor 4); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; diuron; endosulfan.
Type: protein-coding
RefSeq Status: MODEL
Also known as: C-C chemokine receptor type 11; Ccrl1; chemokine (C-C motif) receptor-like 1; LOC685243; similar to C-C chemokine receptor type 11 (C-C CKR-11) (CC-CKR-11) (CCR-11) (Chemokine receptor-like 1) (CCRL1) (CCX CKR)
Orthologs:
Homo sapiens (human) : ACKR4 (atypical chemokine receptor 4)  HGNC  Alliance
Mus musculus (house mouse) : Ackr4 (atypical chemokine receptor 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ackr4 (atypical chemokine receptor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ACKR4 (atypical chemokine receptor 4)
Canis lupus familiaris (dog) : ACKR4 (atypical chemokine receptor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ackr4 (atypical chemokine receptor 4)
Sus scrofa (pig) : ACKR4 (atypical chemokine receptor 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08112,643,838 - 112,651,668 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08112,031,054 - 112,038,505 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48109,160,740 - 109,161,792 (-)NCBIRGSC3.4rn4RGSC3.4
Celera8104,081,309 - 104,089,096 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ackr4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1596453
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.