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Gene: RT1-Db2 (RT1 class II, locus Db2) Rattus norvegicus
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Symbol: RT1-Db2
Name: RT1 class II, locus Db2
Description: Predicted to be involved in antigen processing and presentation and immune response. Predicted to localize to MHC class II protein complex and integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including allergic hypersensitivity disease (multiple); autoimmune hypersensitivity disease (multiple); bacterial infectious disease (multiple); bone inflammation disease (multiple); and eye disease (multiple). Orthologous to human HLA-DRB1 (major histocompatibility complex, class II, DR beta 1) and HLA-DRB5 (major histocompatibility complex, class II, DR beta 5); INTERACTS WITH acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Db2; MHC class II beta chain; RT1 class II, locus Db2 (mapped); RT1-Db2_mapped
Orthologs:
No known orthologs. homologs ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0204,106,136 - 4,126,103 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,106,189 - 4,125,387 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,186,186 - 6,216,870 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,643,873 - 4,662,490 (-)NCBIRGSC3.4rn4RGSC3.4
Celera206,123,209 - 6,141,825 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on RT1-Db2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1595922
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-03-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.