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Gene: Ocrl (OCRL, inositol polyphosphate-5-phosphatase) Rattus norvegicus
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Symbol: Ocrl
Name: OCRL, inositol polyphosphate-5-phosphatase
Description: Predicted to have GTPase activator activity; Rac GTPase binding activity; and phosphatase activity. Predicted to be involved in several processes, including cilium assembly; dephosphorylation; and regulation of GTPase activity. Predicted to localize to several cellular components, including the cytoplasm; photoreceptor outer segment; and plasma membrane. Human ortholog(s) of this gene implicated in Dent disease and oculocerebrorenal syndrome. Orthologous to human OCRL (OCRL inositol polyphosphate-5-phosphatase); PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 2,6-dinitrotoluene; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: inositol polyphosphate 5-phosphatase OCRL-1; Ocrl_mapped; oculocerebrorenal syndrome of Lowe; oculocerebrorenal syndrome of Lowe (mapped)
Orthologs:
Homo sapiens (human) : OCRL (OCRL inositol polyphosphate-5-phosphatase)  HGNC  Alliance
Mus musculus (house mouse) : Ocrl (OCRL, inositol polyphosphate-5-phosphatase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ocrl (OCRL inositol polyphosphate-5-phosphatase)
Pan paniscus (bonobo/pygmy chimpanzee) : OCRL (OCRL inositol polyphosphate-5-phosphatase)
Canis lupus familiaris (dog) : OCRL (OCRL inositol polyphosphate-5-phosphatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ocrl (OCRL inositol polyphosphate-5-phosphatase)
Sus scrofa (pig) : OCRL (OCRL inositol polyphosphate-5-phosphatase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X134,742,226 - 134,793,411 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X134,814,622 - 134,865,807 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X134,271,916 - 134,322,751 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX126,040,210 - 126,091,039 (+)NCBICelera
Cytogenetic MapXq35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ocrl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1594526
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.