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Gene: Ocrl (OCRL, inositol polyphosphate-5-phosphatase) Rattus norvegicus
Symbol: Ocrl
Name: OCRL, inositol polyphosphate-5-phosphatase
Description: Predicted to have GTPase activator activity; Rac GTPase binding activity; and phosphatase activity. Predicted to be involved in several processes, including cilium assembly; dephosphorylation; and regulation of GTPase activity. Predicted to localize to several cellular components, including cytoplasmic vesicle; photoreceptor outer segment; and trans-Golgi network. Human ortholog(s) of this gene implicated in Dent disease and oculocerebrorenal syndrome. Orthologous to human OCRL (OCRL inositol polyphosphate-5-phosphatase); PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 2,6-dinitrotoluene; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: inositol polyphosphate 5-phosphatase OCRL; inositol polyphosphate 5-phosphatase OCRL-1; OCRL-1; Ocrl_mapped; oculocerebrorenal syndrome of Lowe; oculocerebrorenal syndrome of Lowe (mapped); phosphatidylinositol 3,4,5-triphosphate 5-phosphatase
Homo sapiens (human) : OCRL (OCRL inositol polyphosphate-5-phosphatase)  HGNC  Alliance
Mus musculus (house mouse) : Ocrl (OCRL, inositol polyphosphate-5-phosphatase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ocrl (OCRL inositol polyphosphate-5-phosphatase)
Pan paniscus (bonobo/pygmy chimpanzee) : OCRL (OCRL inositol polyphosphate-5-phosphatase)
Canis lupus familiaris (dog) : OCRL (OCRL inositol polyphosphate-5-phosphatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ocrl (OCRL inositol polyphosphate-5-phosphatase)
Sus scrofa (pig) : OCRL (OCRL inositol polyphosphate-5-phosphatase)
Chlorocebus sabaeus (African green monkey) : OCRL (OCRL inositol polyphosphate-5-phosphatase)
Heterocephalus glaber (naked mole-rat) : Ocrl (OCRL inositol polyphosphate-5-phosphatase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X134,742,226 - 134,793,411 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX134,742,356 - 134,792,618 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X134,814,622 - 134,865,807 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X134,271,916 - 134,322,751 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX126,040,210 - 126,091,039 (+)NCBICelera
Cytogenetic MapXq35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ocrl
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1594526
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.