Ints13 (integrator complex subunit 13)

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Gene: Ints13 (integrator complex subunit 13) Rattus norvegicus

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Symbol:

Ints13

Name:

integrator complex subunit 13

RGD ID:

1592236

Description:

Predicted to be involved in centrosome localization and regulation of mitotic cell cycle. Predicted to act upstream of or within mitotic spindle organization and protein localization to nuclear envelope. Predicted to be located in cytoplasm and nuclear body. Predicted to be part of integrator complex. Orthologous to human INTS13 (integrator complex subunit 13); INTERACTS WITH bisphenol A; cadmium dichloride; endosulfan.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Asun; asunder, spermatogenesis regulator; asunder, spermatogenesis regulator homolog (Drosphila); hypothetical protein LOC690728; LOC690728; similar to Protein C12orf11 (Sarcoma antigen NY-SAR-95); uncharacterized protein LOC690728

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	INTS13 (integrator complex subunit 13)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Ints13 (integrator complex subunit 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ints13 (integrator complex subunit 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	INTS13 (integrator complex subunit 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	INTS13 (integrator complex subunit 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ints13 (integrator complex subunit 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	INTS13 (integrator complex subunit 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	INTS13 (integrator complex subunit 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ints13 (integrator complex subunit 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Ints13 (integrator complex subunit 13)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	INTS13 (integrator complex subunit 13)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	R02D3.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	asun	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ints13	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ints13	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	181,190,438 - 181,222,235 (-)	NCBI		GRCr8
mRatBN7.2	4	179,459,740 - 179,491,541 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	179,459,740 - 179,491,541 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	185,745,425 - 185,777,043 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	181,529,950 - 181,561,568 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	180,150,367 - 180,181,986 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	180,854,988 - 180,887,095 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	180,855,800 - 180,887,050 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	245,014,695 - 245,046,802 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	184,121,971 - 184,152,890 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	167,956,851 - 167,988,083 (-)	NCBI		Celera
Cytogenetic Map	4	q44	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chloracne (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2-hydroxypropanoic acid (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

aristolochic acid A (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

chlorpyrifos (ISO)

coumarin (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

endosulfan (EXP)

ethyl methanesulfonate (ISO)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

hydrogen peroxide (ISO)

ivermectin (ISO)

methyl methanesulfonate (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

quercetin (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

testosterone (ISO)

thiram (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

centrosome localization (IBA,ISO)

mitotic spindle organization (ISO)

protein localization to nuclear envelope (ISO)

regulation of mitotic cell cycle (IBA,ISO)

Cellular Component

cytoplasm (ISO)

integrator complex (IBA)

intracellular membrane-bounded organelle (ISO)

nuclear body (IEA,ISO)

nucleoplasm (ISO)

nucleus (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15737938	PMID:23097494	PMID:23904267

Genomics

Comparative Map Data

Ints13
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	181,190,438 - 181,222,235 (-)	NCBI		GRCr8
mRatBN7.2	4	179,459,740 - 179,491,541 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	179,459,740 - 179,491,541 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	185,745,425 - 185,777,043 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	181,529,950 - 181,561,568 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	180,150,367 - 180,181,986 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	180,854,988 - 180,887,095 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	180,855,800 - 180,887,050 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	245,014,695 - 245,046,802 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	184,121,971 - 184,152,890 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	167,956,851 - 167,988,083 (-)	NCBI		Celera
Cytogenetic Map	4	q44	NCBI

INTS13
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	26,905,181 - 26,938,332 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	26,905,181 - 26,938,326 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	27,058,114 - 27,090,914 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	26,949,379 - 26,982,521 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	26,949,384 - 26,982,186	NCBI
Celera	12	32,204,262 - 32,237,410 (-)	NCBI		Celera
Cytogenetic Map	12	p11.23	NCBI
HuRef	12	26,828,162 - 26,861,311 (-)	NCBI		HuRef
CHM1_1	12	27,023,152 - 27,056,298 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	26,777,183 - 26,810,389 (-)	NCBI		T2T-CHM13v2.0

Ints13
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	146,446,253 - 146,479,333 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	146,451,130 - 146,479,333 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	146,549,632 - 146,577,835 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	146,549,632 - 146,577,835 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	146,498,154 - 146,526,357 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	146,506,802 - 146,534,929 (-)	NCBI		MGSCv36	mm8
Celera	6	149,592,491 - 149,630,272 (-)	NCBI		Celera
Cytogenetic Map	6	G3	NCBI
cM Map	6	77.7	NCBI

Ints13
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	21,780,397 - 21,812,727 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	21,779,417 - 21,813,804 (-)	NCBI	ChiLan1.0	ChiLan1.0

INTS13
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	69,875,722 - 69,909,153 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	69,872,161 - 69,907,118 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	59,373,002 - 59,406,131 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	61,986,872 - 62,020,021 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	61,986,877 - 62,020,015 (+)	Ensembl	panpan1.1		panPan2

INTS13
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	20,704,673 - 20,734,119 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	20,706,207 - 20,733,830 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	25,654,817 - 25,682,231 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	20,899,450 - 20,928,700 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	20,899,446 - 20,928,692 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	20,711,942 - 20,739,576 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	20,734,172 - 20,761,808 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	25,817,461 - 25,845,099 (-)	NCBI		UU_Cfam_GSD_1.0

Ints13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	82,615,893 - 82,649,851 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936548	560,746 - 572,752 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

INTS13
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	46,824,150 - 46,860,553 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	46,823,746 - 46,860,552 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	50,376,013 - 50,404,425 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

INTS13
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	26,653,617 - 26,686,830 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	26,653,391 - 26,686,766 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666069	8,384,623 - 8,417,862 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ints13
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	12,258,949 - 12,290,295 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624752	12,257,427 - 12,291,269 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ints13
76 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	41
Count of miRNA genes:	36
Interacting mature miRNAs:	40
Transcripts:	ENSRNOT00000065730
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
6478754	Anxrr43	Anxiety related response QTL 43		0.14035	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	144639524	182687754	Rat
2303623	Vencon2	Ventilatory control QTL 2	3.8		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	4	135204660	180204660	Rat
6478693	Anxrr32	Anxiety related response QTL 32		0.00092	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	144639524	182687754	Rat
2293659	Bmd35	Bone mineral density QTL 35	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	4	137755016	181392681	Rat
1578674	Bmd12	Bone mineral density QTL 12	3.8		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	4	135699135	180699135	Rat
10401796	Kidm48	Kidney mass QTL 48			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	145568712	182687754	Rat
6478718	Anxrr34	Anxiety related response QTL 34		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	144639524	182687754	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	11320076	180699135	Rat
6478748	Anxrr42	Anxiety related response QTL 42		0.28008	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	144639524	182687754	Rat
6478700	Anxrr33	Anxiety related response QTL 33		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	144639524	182687754	Rat
1300109	Rf13	Renal function QTL 13	3.91		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	4	157710145	182687754	Rat
10053718	Scort25	Serum corticosterone level QTL 25	2.15	0.0097	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	155561574	182687754	Rat

Markers in Region

RH137259

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	179,459,858 - 179,460,077 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	180,855,101 - 180,855,319	NCBI	Rnor6.0
Rnor_5.0	4	245,014,808 - 245,015,026	UniSTS	Rnor5.0
RGSC_v3.4	4	184,121,272 - 184,121,490	UniSTS	RGSC3.4
Celera	4	167,956,152 - 167,956,370	UniSTS
Cytogenetic Map	4	q44	UniSTS

AA955382

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	179,459,959 - 179,460,819 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	180,855,202 - 180,856,061	NCBI	Rnor6.0
Rnor_5.0	4	245,014,909 - 245,015,768	UniSTS	Rnor5.0
RGSC_v3.4	4	184,121,373 - 184,122,232	UniSTS	RGSC3.4
Celera	4	167,956,253 - 167,957,112	UniSTS
RH 3.4 Map	4	1067.7	UniSTS
Cytogenetic Map	4	q44	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109608	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001398932	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006237689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108388	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286723	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005503317	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000065730 ⟹ ENSRNOP00000061847

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	179,459,740 - 179,491,541 (-)	Ensembl
Rnor_6.0 Ensembl	4	180,855,800 - 180,887,050 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118399 ⟹ ENSRNOP00000083691

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	179,459,746 - 179,491,372 (-)	Ensembl

RefSeq Acc Id:

NM_001109608 ⟹ NP_001103078

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	181,191,256 - 181,222,166 (-)	NCBI
mRatBN7.2	4	179,460,558 - 179,491,472 (-)	NCBI
Rnor_6.0	4	180,855,800 - 180,887,050 (-)	NCBI
Rnor_5.0	4	245,014,695 - 245,046,802 (-)	NCBI
RGSC_v3.4	4	184,121,971 - 184,152,890 (-)	RGD
Celera	4	167,956,851 - 167,988,083 (-)	RGD

Sequence:

show sequence

GCTACCGGTCTGGACTGAAGGCGGAGAGGGGAGCTTGAGTGGGTGCGCTCTGCCTGTGCAGAGC
CGAGGCCGGCTTATCCCGGCTGCGGCTAGTACTTTGGGGGTTCTCTCAGGTGGTCCTGACCATT
CTTCCCAACGGTCGATTGGGAACAATCGTTAGAGCCTTCTTTTTTTTCCCCTCACTTGCTCCGC
CCTCTTCCGGTTCGGCCTCTGGTAGCCTCTAAGGGGAAGGGGAAGATGGCGGGACTGTGCGAGA
GCGCCGTGCGCACGCGCGAGCCCGAGTGCGCTTTGGTGGGTGCACGCGCATGCGCGCGCTCCTG
CGTTTAAGAAGCCGGAGTGTTGGGCGATGAGCCGGGCAGTCAGTCTTCTGCGGGTGGTACCAGA
CCGTCTGTGCGCCGACTCCCCACCCACCCTCGTCTGCCTTCTCCCTTAGCCTCCGTTCGCTCAC
TACAGGACCAGGCACGAAAATTAAAACAAAATGAAGATTTTTTCTGAATCTCATAAAACAGTGT
TTGTTGTGGATCACTGCCCATACATGGCAGAATCCTGTAGACAGCATGTGGAGTTTGATATGCT
GGTGAAGAACAGGACCCAAGGAATCATCCCTTTGGCTCCCATCTCCAAATCTTTGTGGACTTGC
TCAGTAGAATCTTCCATGGAATATTGTAGAATAATGTATGATATATTTCCTTTCAAAAAACTGG
TGAATTTCATTGTGAGTGACTCGGGAGCACATGTTTTAAACTCTTGGACTCAAGAAGACCAAAA
CTTACAGGAGCTAATGGCAGCACTAGCTACTGTGGGGCCTCCTAACCCTCGGGCAGATCCAGAG
TGCTGCAGCATTCTGCATGGTCTTGTTGCAGCAGTGGAAACCCTTTGCAAAATTACCGAATACC
AACATGAGGCTCGTACTTTACTCATGGAGAATGCAGAACGAGTTGGGAATAGAGGACGGATAAT
CTGCATTACAAATGCAAAAAGTGATAGTCATGTACGAATGCTTGAAGACTGTGTCCAGGAAACA
ATTCATGAACATAACAAGCTCGCTGCAAATTCAGATCATCTCATGCAGATTCAAAAATGTGAGT
TGGTCTTGATTCACACCTATCCAGTTGGTGAAGATAGCCTTGTGTCTGATCGTCCTAAAAAGGA
ATTGTCCCCAGTTTTGACCAGTGAAGTCCATAGTGTCCGAGCTGGGCGGCATCTTGCTACCAAG
TTGAATGTTCTAGTACAGCAACACTTCGACTTGGCTTCAACGACCATCACAAACATCCCTATGA
AGGAAGAGCAGCACGCCAACACATCCGCCAACTACGACGTGGAGCTGCTCCATCACAAGGATGC
ACATGTAGACTTCCTGAGAAGTGGTGACGGCCACTCAGGGGGCAGCAGCAGAGAAGGGCCATTT
AAAGAGACAGTAACCCTGAAGTGGTGCACACCCAGGACCAACAGCATTGAATTACACTACTGCA
CTGGCGCTTACCGAATCTCACCTGTTGATGTAAATAGTAGACCTTCTTCCTGCCTCACTAATTT
TCTCCTCAATGGTCGGTCTGTGTTGCTGGAGCAGCCACGAAAGTCAGGTTCCAAAGTCATCAGT
CACATGCTTAGCAGCCATGGAGGAGAGATCTTTTTGCATGTCCTTAGCAGTTCTCGATCCATTC
TAGAAGATCCGCCTTCAATTAGTGAGGGCTGTGGAGGAAGAGTTACAGATTATCGGATTACAGA
TTTTGGTGAATTTATGAGGGAAAACAGGTTAACTCCTTTTCTAGACCCCAGATATAAAATGGAT
GCAAGTCTAGAGATCCCGTTGGAACGTGCAAAGGATCAGTTAGAAAAGCACACCCGTTACTGGC
CCATGATTATTTCACAAACCACCATTTTCAACATGCAAGCGGTAGTTCCATTAGCTGGTGTCAT
TGTGAAAGAGTCTTTGACAGAAGAGGATGTGTTAAACTGTCAGAAAACTATATACAACTTAGTC
GATATGGAAAGAAAGAATGACCCTCTTCCTGTTTCTACAGTTGGTACCAGAGGAAAGGGGCCGA
AAAGAGATGAACAGTACCGGATCATGTGGAATGAACTAGAGACTCTTGTAAGAGCCCATATCAG
CAACTCTGAGAAGCATCAGAGAGTTTTGGAGTGTCTGATGGCGTGTAGGAGCAAACCCCCAGAA
GAAGAAGAACGGAAGAAGCGAGGAAGGAAGAGGGAGGACAGAGAGGACAAGTCTGAACAAGCTG
GGAAGGAGCACGGCTCGGAAAAACCCCGGCCAGACGCAGATAGATTGAAAGGGATTTTAGAACG
AGGGAAAGAAGAGTTGGCCGAAGCGGAGGTCATAAAGGACTCACCTGATTCTCCAGAACCTCCA
AACAAAAAGCCCCTTGTTGAAATGGATGAGACACCACACATGGAAAAGTCTAAAGGGCCAGTGT
CCTTATTATCCTTGTGGAGTAACAGAATAAACACTGCCAATTCCAGAAAGCACCAGGAGTTTGC
TGGGCGTTTGAACTCTGTCAATAACAGAGCAGAGCTATATCAACACCTTAAGGAGGAAAATGGG
TTTGTGTAATTTCCTGTGGAAACTGCTTTGTTGATTGTGTAGTCCCGTAATGAAACTGCTCACT
TTTGGTCAGCAGTTTTGTTCTGCTATTATGAGCTAATTCTTACATTGCCTCTAAGGAGAAAGAT
ATAACCTGTTAGACCCATGGCTCTCACAAAAGGCAGGCCCAGTTTATTGACTGTGATTATGAAG
CTGTCTGC

hide sequence

RefSeq Acc Id:

NM_001398932 ⟹ NP_001385861

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	181,190,438 - 181,222,235 (-)	NCBI
mRatBN7.2	4	179,459,740 - 179,491,541 (-)	NCBI

RefSeq Acc Id:

XM_039108388 ⟹ XP_038964316

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	181,190,444 - 181,221,837 (-)	NCBI
mRatBN7.2	4	179,459,740 - 179,491,538 (-)	NCBI

RefSeq Acc Id:

XM_063286723 ⟹ XP_063142793

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	181,190,444 - 181,219,052 (-)	NCBI

RefSeq Acc Id:

XR_005503317

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	181,195,630 - 181,221,837 (-)	NCBI
mRatBN7.2	4	179,464,890 - 179,491,541 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001103078	(Get FASTA)	NCBI Sequence Viewer
	NP_001385861	(Get FASTA)	NCBI Sequence Viewer
	XP_038964316	(Get FASTA)	NCBI Sequence Viewer
	XP_063142793	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM01419	(Get FASTA)	NCBI Sequence Viewer
	EDM01420	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000061847.2
	ENSRNOP00000083691.1

RefSeq Acc Id:	NP_001103078 ⟸ NM_001109608
- Peptide Label:	isoform 2
- UniProtKB:	D4A6N9 (UniProtKB/TrEMBL), A6IN19 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKIFSESHKTVFVVDHCPYMAESCRQHVEFDMLVKNRTQGIIPLAPISKSLWTCSVESSMEYCR IMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALATVGPPNPRADPECCSILHGLVA AVETLCKITEYQHEARTLLMENAERVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAAN SDHLMQIQKCELVLIHTYPVGEDSLVSDRPKKELSPVLTSEVHSVRAGRHLATKLNVLVQQHFD LASTTITNIPMKEEQHANTSANYDVELLHHKDAHVDFLRSGDGHSGGSSREGPFKETVTLKWCT PRTNSIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEI FLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKMDASLEIPLERA KDQLEKHTRYWPMIISQTTIFNMQAVVPLAGVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLP VSTVGTRGKGPKRDEQYRIMWNELETLVRAHISNSEKHQRVLECLMACRSKPPEEEERKKRGRK REDREDKSEQAGKEHGSEKPRPDADRLKGILERGKEELAEAEVIKDSPDSPEPPNKKPLVEMDE TPHMEKSKGPVSLLSLWSNRINTANSRKHQEFAGRLNSVNNRAELYQHLKEENGFV hide sequence

Ensembl Acc Id:

ENSRNOP00000061847 ⟸ ENSRNOT00000065730

RefSeq Acc Id:	XP_038964316 ⟸ XM_039108388
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZWB2 (UniProtKB/TrEMBL), A6IN18 (UniProtKB/TrEMBL), D4A6N9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000083691 ⟸ ENSRNOT00000118399

RefSeq Acc Id:	NP_001385861 ⟸ NM_001398932
- Peptide Label:	isoform 1
- UniProtKB:	D4A6N9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142793 ⟸ XM_063286723
- Peptide Label:	isoform X2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A6N9-F1-model_v2	AlphaFold	D4A6N9	1-696	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693504

Promoter ID:

EPDNEW_R4026

Type:

initiation region

Name:

Ints13_1

Description:

integrator complex subunit 13

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	180,887,074 - 180,887,134	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1592236	AgrOrtholog
BioCyc Gene	G2FUF-42430	BioCyc
Ensembl Genes	ENSRNOG00000001808	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000065730.2	UniProtKB/TrEMBL
	ENSRNOT00000118399.1	UniProtKB/TrEMBL
InterPro	Cell_cycle_regulator_Mat89Bb	UniProtKB/TrEMBL
NCBI Gene	690728	ENTREZGENE
PANTHER	INTEGRATOR COMPLEX SUBUNIT 13	UniProtKB/TrEMBL
	PTHR12955	UniProtKB/TrEMBL
Pfam	DUF2151	UniProtKB/TrEMBL
PhenoGen	Ints13	PhenoGen
RatGTEx	ENSRNOG00000001808	RatGTEx
UniProt	A0A8I5ZWB2	ENTREZGENE, UniProtKB/TrEMBL
	A6IN18	ENTREZGENE, UniProtKB/TrEMBL
	A6IN19	ENTREZGENE, UniProtKB/TrEMBL
	D4A6N9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-01-03	Ints13	integrator complex subunit 13	Asun	asunder, spermatogenesis regulator	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-12-18	Asun	asunder, spermatogenesis regulator	Asun	asunder, spermatogenesis regulator homolog (Drosphila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-10-02	Asun	asunder, spermatogenesis regulator homolog (Drosphila)	LOC690728	similar to Protein C12orf11 (Sarcoma antigen NY-SAR-95)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC690728	similar to Protein C12orf11 (Sarcoma antigen NY-SAR-95)	LOC686480	similar to Protein C12orf11 (Sarcoma antigen NY-SAR-95)	Data merged from RGD:1597604	1643240	APPROVED
2006-11-20	LOC690728	similar to Protein C12orf11 (Sarcoma antigen NY-SAR-95)			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC686480	similar to Protein C12orf11 (Sarcoma antigen NY-SAR-95)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD