Dach1 (dachshund family transcription factor 1)

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Gene: Dach1 (dachshund family transcription factor 1) Rattus norvegicus

Analyze

Symbol:

Dach1

Name:

dachshund family transcription factor 1

RGD ID:

1592073

Description:

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of cell migration and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within several processes, including negative regulation of cell population proliferation; suckling behavior; and type B pancreatic cell proliferation. Predicted to be located in Golgi apparatus; cytosol; and nuclear speck. Predicted to be part of transcription regulator complex. Orthologous to human DACH1 (dachshund family transcription factor 1); INTERACTS WITH atrazine; bisphenol A; DDT.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

dachshund homolog 1; dachshund homolog 1 (Drosophila); LOC306096; similar to Dachshund homolog 1 (Dach1)

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	15	74,528,122 - 74,909,811 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	74,529,208 - 74,909,922 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	15	82,095,003 - 82,482,272 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	82,099,159 - 82,482,009 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	85,630,327 - 86,015,440 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	81,193,149 - 81,573,098 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	15	73,782,806 - 74,166,266 (-)	NCBI		Celera
Cytogenetic Map	15	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 13q14 deletion syndrome (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

atrazine (EXP,ISO)

azoxystrobin (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

Benzo[k]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

chloroprene (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

cyclosporin A (ISO)

DDT (EXP)

diallyl trisulfide (ISO)

dibenz[a,h]anthracene (ISO)

dorsomorphin (ISO)

entinostat (ISO)

folic acid (ISO)

fulvestrant (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

nickel atom (ISO)

nickel dichloride (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

phenylmercury acetate (ISO)

potassium dichromate (ISO)

progesterone (ISO)

rotenone (EXP)

SB 431542 (ISO)

temozolomide (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

tunicamycin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

development of primary female sexual characteristics (ISO)

epithelial cell proliferation (ISO)

negative regulation of cell migration (ISO)

negative regulation of cell proliferation involved in contact inhibition (ISO)

negative regulation of DNA biosynthetic process (ISO)

negative regulation of DNA-templated transcription (ISO)

negative regulation of fibroblast proliferation (ISO)

negative regulation of transcription by competitive promoter binding (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

regulation of DNA-templated transcription (ISO)

regulation of nuclear cell cycle DNA replication (ISO)

respiratory gaseous exchange by respiratory system (ISO)

suckling behavior (ISO)

type B pancreatic cell proliferation (ISO)

Cellular Component

cytoplasm (ISO)

cytosol (IEA,ISO)

Golgi apparatus (IEA,ISO)

nuclear speck (IEA,ISO)

nucleoplasm (ISO)

nucleus (ISO)

transcription regulator complex (IBA,ISO)

Molecular Function

DNA-binding transcription factor activity (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (ISO)

DNA-binding transcription repressor activity, RNA polymerase II-specific (ISO)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11025202	PMID:11238885	PMID:11543628	PMID:12203718	PMID:14628042	PMID:16024294	PMID:16980615	PMID:17182846	PMID:18395837	PMID:20869363	PMID:20956529	PMID:21750150

Genomics

Comparative Map Data

Dach1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	15	74,528,122 - 74,909,811 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	74,529,208 - 74,909,922 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	15	82,095,003 - 82,482,272 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	82,099,159 - 82,482,009 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	85,630,327 - 86,015,440 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	81,193,149 - 81,573,098 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	15	73,782,806 - 74,166,266 (-)	NCBI		Celera
Cytogenetic Map	15	q21	NCBI

DACH1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	71,437,966 - 71,867,204 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	13	71,437,966 - 71,867,204 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	72,012,098 - 72,441,342 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	70,910,099 - 71,339,331 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	13	52,914,100 - 53,343,311 (-)	NCBI		Celera
Cytogenetic Map	13	q21.33	NCBI
HuRef	13	52,714,019 - 53,142,879 (-)	NCBI		HuRef
CHM1_1	13	71,980,085 - 72,408,806 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	13	70,663,152 - 71,092,075 (-)	NCBI		T2T-CHM13v2.0

Dach1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	98,024,282 - 98,407,608 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	98,024,289 - 98,407,201 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	97,786,846 - 98,169,765 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	97,786,853 - 98,169,765 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	98,186,066 - 98,568,762 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	96,669,981 - 97,052,677 (-)	NCBI		MGSCv36	mm8
Celera	14	96,458,913 - 96,841,080 (-)	NCBI		Celera
Cytogenetic Map	14	E2.1	NCBI
cM Map	14	48.25	NCBI

Dach1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955404	34,740,026 - 35,137,490 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955404	34,739,780 - 35,118,037 (+)	NCBI	ChiLan1.0	ChiLan1.0

DACH1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	13	71,445,338 - 71,872,200 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	13	52,666,569 - 53,098,257 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

DACH1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	25,690,700 - 25,934,449 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	25,726,597 - 25,934,550 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	25,548,120 - 25,971,191 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	26,032,633 - 26,451,423 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	22	26,035,267 - 26,451,372 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	22	25,657,470 - 26,080,260 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	25,729,296 - 26,152,543 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	25,802,120 - 26,225,501 (-)	NCBI		UU_Cfam_GSD_1.0

Dach1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	133,481,740 - 133,870,853 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936511	9,061,676 - 9,253,486 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936511	8,899,245 - 9,253,024 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DACH1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	43,764,271 - 44,187,821 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	11	43,765,386 - 44,187,766 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	48,207,856 - 48,598,451 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DACH1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	50,591,136 - 51,020,042 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666046	6,672,701 - 7,107,250 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dach1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624751	28,703,108 - 29,080,750 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624751	28,702,797 - 29,080,751 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Dach1
2210 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	16
Count of miRNA genes:	16
Interacting mature miRNAs:	16
Transcripts:	ENSRNOT00000011926
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	16725528	80672115	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	22806240	98288169	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	22806240	98288169	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	22806240	98288169	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	28030665	82262678	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	28030665	82262678	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	28030665	82262678	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
1598828	Glom14	Glomerulus QTL 14	2.5		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	15	34054139	79054139	Rat
1300144	Rf23	Renal function QTL 23	3.61		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	15	40631268	98288169	Rat
1576315	Schws6	Schwannoma susceptibility QTL 6		0.0069	nervous system integrity trait (VT:0010566)	post-insult time of death (CMO:0002005)	15	53806152	98806152	Rat
61477	Aia4	Adjuvant induced arthritis QTL 4	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	15	55596089	91365858	Rat
631516	Gluco31	Glucose level QTL 31	7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	55596089	95018120	Rat
631655	Bp126	Blood pressure QTL 126	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	58156477	101769107	Rat
731177	Uae26	Urinary albumin excretion QTL 26	2.4	0.025	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	15	67588667	101769107	Rat
2300326	Plaw1	Placental weight QTL 1	15	0.005	placenta mass (VT:0004257)	placenta wet weight (CMO:0002088)	15	68327165	100062518	Rat
1331724	Bp223	Blood pressure QTL 223	3.53715		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	73690518	95018228	Rat
1641889	Colcr6	Colorectal carcinoma resistance QTL 6	2.9	0.0126	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	15	73690518	99794247	Rat
70182	BpQTLcluster12	Blood pressure QTL cluster 12	3.53		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	15	73690657	95018120	Rat

Markers in Region

D15Got75

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	74,907,682 - 74,907,853 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	82,481,065 - 82,481,235	NCBI	Rnor6.0
Rnor_5.0	15	86,014,233 - 86,014,403	UniSTS	Rnor5.0
RGSC_v3.4	15	81,571,984 - 81,572,155	RGD	RGSC3.4
RGSC_v3.4	15	81,571,985 - 81,572,155	UniSTS	RGSC3.4
RGSC_v3.1	15	81,587,764 - 81,587,935	RGD
Celera	15	74,164,010 - 74,164,182	UniSTS
RH 2.0 Map	15	428.6	RGD
Cytogenetic Map	15	q21	UniSTS

AI182278

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	74,528,206 - 74,528,496 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	82,096,527 - 82,096,816	NCBI	Rnor6.0
Rnor_5.0	15	85,630,400 - 85,630,689	UniSTS	Rnor5.0
RGSC_v3.4	15	81,191,047 - 81,191,336	UniSTS	RGSC3.4
Celera	15	73,784,330 - 73,784,619	UniSTS
Cytogenetic Map	15	q21	UniSTS

RH144008

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	74,808,794 - 74,809,011 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	82,382,141 - 82,382,357	NCBI	Rnor6.0
Rnor_5.0	15	85,915,309 - 85,915,525	UniSTS	Rnor5.0
RGSC_v3.4	15	81,472,957 - 81,473,173	UniSTS	RGSC3.4
Celera	15	74,064,641 - 74,064,857	UniSTS
RH 3.4 Map	15	500.71	UniSTS
Cytogenetic Map	15	q21	UniSTS

BF386288

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	74,834,696 - 74,834,892 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	82,408,041 - 82,408,237	NCBI	Rnor6.0
Rnor_5.0	15	85,941,209 - 85,941,405	UniSTS	Rnor5.0
RGSC_v3.4	15	81,498,830 - 81,499,301	UniSTS	RGSC3.4
Celera	15	74,090,541 - 74,090,736	UniSTS
Cytogenetic Map	15	q21	UniSTS

BE102739

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	74,851,855 - 74,852,009 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	82,425,531 - 82,425,684	NCBI	Rnor6.0
Rnor_5.0	15	85,958,699 - 85,958,852	UniSTS	Rnor5.0
RGSC_v3.4	15	81,516,262 - 81,516,415	UniSTS	RGSC3.4
Celera	15	74,107,695 - 74,107,848	UniSTS
RH 3.4 Map	15	500.07	UniSTS
Cytogenetic Map	15	q21	UniSTS

BE108573

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	74,750,476 - 74,750,629 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	82,323,610 - 82,323,762	NCBI	Rnor6.0
Rnor_5.0	15	85,856,778 - 85,856,930	UniSTS	Rnor5.0
RGSC_v3.4	15	81,414,641 - 81,414,793	UniSTS	RGSC3.4
Celera	15	74,006,416 - 74,006,568	UniSTS
RH 3.4 Map	15	500.11	UniSTS
Cytogenetic Map	15	q21	UniSTS

BE118787

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	74,571,247 - 74,571,420 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	82,139,563 - 82,139,735	NCBI	Rnor6.0
Rnor_5.0	15	85,673,436 - 85,673,608	UniSTS	Rnor5.0
RGSC_v3.4	15	81,234,141 - 81,234,313	UniSTS	RGSC3.4
Celera	15	73,827,417 - 73,827,589	UniSTS
RH 3.4 Map	15	500.01	UniSTS
Cytogenetic Map	15	q21	UniSTS

BE107302

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	74,773,100 - 74,773,280 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	82,346,235 - 82,346,414	NCBI	Rnor6.0
Rnor_5.0	15	85,879,403 - 85,879,582	UniSTS	Rnor5.0
RGSC_v3.4	15	81,437,263 - 81,437,442	UniSTS	RGSC3.4
Celera	15	74,029,035 - 74,029,214	UniSTS
RH 3.4 Map	15	500.71	UniSTS
Cytogenetic Map	15	q21	UniSTS

DACH1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	74,528,220 - 74,528,439 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	82,096,541 - 82,096,759	NCBI	Rnor6.0
Rnor_5.0	15	85,630,414 - 85,630,632	UniSTS	Rnor5.0
RGSC_v3.4	15	81,191,061 - 81,191,279	UniSTS	RGSC3.4
Celera	15	73,784,344 - 73,784,562	UniSTS
Cytogenetic Map	15	q21	UniSTS

D13S1087E

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	74,529,793 - 74,529,913 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	82,098,114 - 82,098,233	NCBI	Rnor6.0
Rnor_5.0	15	85,631,987 - 85,632,106	UniSTS	Rnor5.0
RGSC_v3.4	15	81,192,634 - 81,192,753	UniSTS	RGSC3.4
Celera	15	73,785,917 - 73,786,036	UniSTS
Cytogenetic Map	15	q21	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			2						55	35	20	11
Low	3	43	36	22	19	22	8	10	19		20		8
Below cutoff			18	18		18		1			1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008770204	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770929	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACYVU010000272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000011926 ⟹ ENSRNOP00000011926

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	74,529,208 - 74,909,922 (-)	Ensembl
Rnor_6.0 Ensembl	15	82,099,159 - 82,482,009 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000108512 ⟹ ENSRNOP00000081723

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	74,529,208 - 74,909,922 (-)	Ensembl

RefSeq Acc Id:

XM_039093963 ⟹ XP_038949891

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	74,528,122 - 74,909,811 (-)	NCBI

RefSeq Acc Id:

XM_039093964 ⟹ XP_038949892

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	74,528,122 - 74,909,805 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_038949891	(Get FASTA)	NCBI Sequence Viewer
	XP_038949892	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

ENSRNOP00000011926 ⟸ ENSRNOT00000011926

RefSeq Acc Id:	XP_038949891 ⟸ XM_039093963
- Peptide Label:	isoform X1
- UniProtKB:	F1M0Y6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038949892 ⟸ XM_039093964
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZUP7 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000081723 ⟸ ENSRNOT00000108512

Protein Domains

SKI/SNO/DAC

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M0Y6-F1-model_v2	AlphaFold	F1M0Y6	1-531	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1592073	AgrOrtholog
BioCyc Gene	G2FUF-12802	BioCyc
Ensembl Genes	ENSRNOG00000008834	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000011926	ENTREZGENE
	ENSRNOP00000011926.7	UniProtKB/TrEMBL
	ENSRNOP00000081723	ENTREZGENE
	ENSRNOP00000081723.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000011926	ENTREZGENE
	ENSRNOT00000011926.8	UniProtKB/TrEMBL
	ENSRNOT00000108512	ENTREZGENE
	ENSRNOT00000108512.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.260.20	UniProtKB/TrEMBL
InterPro	DNA-bd_dom_put	UniProtKB/TrEMBL
	Ski_DNA-bd_sf	UniProtKB/TrEMBL
	Transform_Ski	UniProtKB/TrEMBL
NCBI Gene	306096	ENTREZGENE
PANTHER	DACHSHUND	UniProtKB/TrEMBL
	DACHSHUND HOMOLOG 1	UniProtKB/TrEMBL
Pfam	Ski_Sno	UniProtKB/TrEMBL
PhenoGen	Dach1	PhenoGen
Superfamily-SCOP	SSF46955	UniProtKB/TrEMBL
UniProt	A0A8I5ZUP7	ENTREZGENE, UniProtKB/TrEMBL
	F1M0Y6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2014-02-13	Dach1	dachshund family transcription factor 1	Dach1	dachshund homolog 1 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-12-11	Dach1	dachshund homolog 1 (Drosophila)	LOC306096	similar to Dachshund homolog 1 (Dach1)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC306096	similar to Dachshund homolog 1 (Dach1)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar