Rplp2l2 (ribosomal protein lateral stalk subunit P2 like 2) - Rat Genome Database

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Gene: Rplp2l2 (ribosomal protein lateral stalk subunit P2 like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rplp2l2
Name: ribosomal protein lateral stalk subunit P2 like 2
RGD ID: 1590791
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translational elongation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Orthologous to human RPLP2 (ribosomal protein lateral stalk subunit P2).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 60S acidic ribosomal protein P2-like; large ribosomal subunit protein P2-like; LOC498555; ribosomal protein lateral stalk subunit P2 like 1; Rplp2l1; similar to 60S acidic ribosomal protein P2
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81574,046,772 - 74,047,261 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1574,046,766 - 74,056,735 (+)EnsemblGRCr8
mRatBN7.21567,638,365 - 67,638,804 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1567,638,364 - 67,638,823 (+)EnsemblmRatBN7.2
Rnor_6.01575,067,284 - 75,067,724 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1575,067,297 - 75,067,723 (+)Ensemblrn6Rnor6.0
Rnor_5.01578,627,980 - 78,628,416 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41574,072,039 - 74,072,476 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1567,074,653 - 67,075,093 (+)NCBICelera
Cytogenetic Map15q21NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:35352799  


Genomics

Variants

.
Variants in Rplp2l2
1 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:10
Count of miRNA genes:10
Interacting mature miRNAs:10
Transcripts:ENSRNOT00000057931
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1567588667101769107Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)155380615298806152Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
61477Aia4Adjuvant induced arthritis QTL 43joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)155559608991365858Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155079449473699215Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)152788577486257085Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1558156477101769107Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
631516Gluco31Glucose level QTL 317blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)155559608995018120Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2317050Aia24Adjuvant induced arthritis QTL 242.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)155284790873690657Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
2313080Bss65Bone structure and strength QTL 653.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)156099046873690657Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat

Markers in Region
RH127513  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21567,638,524 - 67,638,739 (-)MAPPERmRatBN7.2
mRatBN7.21567,638,524 - 67,638,739 (+)MAPPERmRatBN7.2
mRatBN7.21442,745,339 - 42,745,554 (+)MAPPERmRatBN7.2
Rnor_6.01444,375,488 - 44,375,702NCBIRnor6.0
Rnor_6.01575,067,443 - 75,067,657NCBIRnor6.0
Rnor_5.01444,195,035 - 44,195,249UniSTSRnor5.0
Rnor_5.01578,628,135 - 78,628,349UniSTSRnor5.0
RGSC_v3.41445,439,196 - 45,439,410UniSTSRGSC3.4
RGSC_v3.41574,072,195 - 74,072,409UniSTSRGSC3.4
Celera1567,074,812 - 67,075,026UniSTS
Celera1441,896,305 - 41,896,519UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map1q41UniSTS
RH129225  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21567,638,528 - 67,638,740 (+)MAPPERmRatBN7.2
mRatBN7.21442,745,338 - 42,745,550 (-)MAPPERmRatBN7.2
mRatBN7.21442,745,338 - 42,745,550 (+)MAPPERmRatBN7.2
mRatBN7.21567,638,528 - 67,638,740 (-)MAPPERmRatBN7.2
Rnor_6.01575,067,447 - 75,067,658NCBIRnor6.0
Rnor_6.01444,375,487 - 44,375,698NCBIRnor6.0
Rnor_5.01444,195,034 - 44,195,245UniSTSRnor5.0
Rnor_5.01578,628,139 - 78,628,350UniSTSRnor5.0
RGSC_v3.41445,439,195 - 45,439,406UniSTSRGSC3.4
RGSC_v3.41574,072,199 - 74,072,410UniSTSRGSC3.4
Celera1567,074,816 - 67,075,027UniSTS
Celera1441,896,304 - 41,896,515UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map1q41UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000057931   ⟹   ENSRNOP00000054740
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1574,046,766 - 74,056,735 (+)Ensembl
mRatBN7.2 Ensembl1567,638,364 - 67,638,823 (+)Ensembl
Rnor_6.0 Ensembl1575,067,297 - 75,067,723 (+)Ensembl
RefSeq Acc Id: XM_039093959   ⟹   XP_038949887
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81574,046,772 - 74,047,261 (+)NCBI
mRatBN7.21567,638,365 - 67,638,804 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038949887 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000054740
  ENSRNOP00000054740.2
Ensembl Acc Id: ENSRNOP00000054740   ⟸   ENSRNOT00000057931
RefSeq Acc Id: XP_038949887   ⟸   XM_039093959
- UniProtKB: D4A4D5 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A4D5-F1-model_v2 AlphaFold D4A4D5 1-115 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699862
Promoter ID:EPDNEW_R10380
Type:initiation region
Name:LOC498555_1
Description:similar to 60S acidic ribosomal protein P2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01575,067,283 - 75,067,343EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1590791 AgrOrtholog
BioCyc Gene G2FUF-12878 BioCyc
Ensembl Genes ENSRNOG00000038074 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057931 ENTREZGENE
  ENSRNOT00000057931.5 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1410 UniProtKB/TrEMBL
InterPro P1/P2_N_sf UniProtKB/TrEMBL
  Ribosomal_L12 UniProtKB/TrEMBL
  Ribosomal_P2 UniProtKB/TrEMBL
NCBI Gene 498555 ENTREZGENE
PANTHER 60S ACIDIC RIBOSOMAL PROTEIN P2 UniProtKB/TrEMBL
  PTHR21141 UniProtKB/TrEMBL
Pfam Ribosomal_60s UniProtKB/TrEMBL
PhenoGen Rplp2l2 PhenoGen
RatGTEx ENSRNOG00000038074 RatGTEx
UniProt D4A4D5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-13 Rplp2l2  ribosomal protein lateral stalk subunit P2 like 2  Rplp2l1  ribosomal protein lateral stalk subunit P2 like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Rplp2l1  ribosomal protein lateral stalk subunit P2 like 1  LOC498555  similar to 60S acidic ribosomal protein P2  Symbol and Name Changed 1299863 APPROVED
2006-11-20 LOC498555  similar to 60S acidic ribosomal protein P2      Symbol and Name status set to provisional 70820 PROVISIONAL