Tpt1l2 (tumor protein, translationally-controlled 1 like 2) - Rat Genome Database

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Gene: Tpt1l2 (tumor protein, translationally-controlled 1 like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Tpt1l2 (Ensembl: AABR07024742.1)
Name: tumor protein, translationally-controlled 1 like 2
RGD ID: 1590250
Description: Predicted to enable calcium ion binding activity. Predicted to be active in cytoplasm. Orthologous to several human genes including TPT1 (tumor protein, translationally-controlled 1).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC685718; similar to tumor protein, translationally-controlled 1; Tpt1l1; translationally-controlled tumor protein-like; tumor protein, translationally-controlled 1 like 1
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81612,496,929 - 12,497,533 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1612,496,948 - 12,497,482 (+)EnsemblGRCr8
mRatBN7.21612,476,660 - 12,477,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1612,476,735 - 12,477,253 (+)EnsemblmRatBN7.2
Rnor_6.01613,950,401 - 13,950,949 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01613,841,678 - 13,842,196 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41612,907,137 - 12,912,718 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1612,734,189 - 12,734,737 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Tpt1l2
3 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16423421216278352Rat
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16423421216278352Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421216061395Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16423433317730812Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 3 23 46 80 50 1 31 23 26 2 2

Sequence


Ensembl Acc Id: ENSRNOT00000048912   ⟹   ENSRNOP00000094066
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1612,496,948 - 12,497,482 (+)Ensembl
mRatBN7.2 Ensembl1612,476,735 - 12,477,253 (+)Ensembl
Rnor_6.0 Ensembl1613,950,416 - 13,950,934 (+)Ensembl
RefSeq Acc Id: XM_039094897   ⟹   XP_038950825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81612,496,929 - 12,497,533 (+)NCBI
mRatBN7.21612,476,660 - 12,477,351 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038950825 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000082883.1
  ENSRNOP00000094066
  ENSRNOP00000094066.1
RefSeq Acc Id: XP_038950825   ⟸   XM_039094897
- UniProtKB: A0A8I6AN27 (UniProtKB/TrEMBL),   A0A8I5ZVT0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000094066   ⟸   ENSRNOT00000048912
Protein Domains
TCTP

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1590250 AgrOrtholog
BioCyc Gene G2FUF-12003 BioCyc
Ensembl Genes ENSRNOG00000001049 UniProtKB/TrEMBL
  ENSRNOG00000030299 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048912 ENTREZGENE
  ENSRNOT00000048912.6 UniProtKB/TrEMBL
  ENSRNOT00000106386.1 UniProtKB/TrEMBL
Gene3D-CATH Metal Binding Protein, Guanine Nucleotide Exchange Factor, Chain A UniProtKB/TrEMBL
InterPro Mss4-like_sf UniProtKB/TrEMBL
  Mss4/transl-control_tumour UniProtKB/TrEMBL
  TCTP UniProtKB/TrEMBL
  Translation_control_tumour_CS UniProtKB/TrEMBL
  Translational_control_tumour_p UniProtKB/TrEMBL
NCBI Gene 685718 ENTREZGENE
PANTHER PTHR11991 UniProtKB/TrEMBL
  TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN UniProtKB/TrEMBL
Pfam TCTP UniProtKB/TrEMBL
PhenoGen Tpt1l2 PhenoGen
PRINTS TCTPROTEIN UniProtKB/TrEMBL
PROSITE TCTP_1 UniProtKB/TrEMBL
  TCTP_2 UniProtKB/TrEMBL
  TCTP_3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001049 RatGTEx
  ENSRNOG00000030299 RatGTEx
Superfamily-SCOP SSF51316 UniProtKB/TrEMBL
UniProt A0A8I5ZVT0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AN27 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-17 Tpt1l2  tumor protein, translationally-controlled 1 like 2  Tpt1l1  tumor protein, translationally-controlled 1 like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Tpt1l1  tumor protein, translationally-controlled 1 like 1  LOC685718  similar to tumor protein, translationally-controlled 1  Symbol and Name Changed 1299863 APPROVED
2006-11-20 LOC685718  similar to tumor protein, translationally-controlled 1      Symbol and Name status set to provisional 70820 PROVISIONAL