Zfp804b (zinc finger protein 804B) - Rat Genome Database

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Pathways
Gene: Zfp804b (zinc finger protein 804B) Rattus norvegicus
Analyze
Symbol: Zfp804b
Name: zinc finger protein 804B
RGD ID: 1589640
Description: Predicted to enable zinc ion binding activity. Predicted to be active in nucleus. Orthologous to human ZNF804B (zinc finger protein 804B); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; glyphosate; valproic acid.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hypothetical LOC499994; LOC499994
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8427,563,948 - 28,099,625 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl427,564,465 - 28,097,319 (+)EnsemblGRCr8
mRatBN7.2426,608,510 - 27,144,717 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl426,609,744 - 27,141,673 (+)EnsemblmRatBN7.2
Rnor_6.0423,678,899 - 24,236,853 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl424,222,500 - 24,232,017 (+)Ensemblrn6Rnor6.0
Rnor_5.0423,609,795 - 24,155,906 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4423,229,255 - 23,773,114 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera422,087,490 - 22,618,496 (+)NCBICelera
Cytogenetic Map4q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations

Genomics

Comparative Map Data
Zfp804b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8427,563,948 - 28,099,625 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl427,564,465 - 28,097,319 (+)EnsemblGRCr8
mRatBN7.2426,608,510 - 27,144,717 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl426,609,744 - 27,141,673 (+)EnsemblmRatBN7.2
Rnor_6.0423,678,899 - 24,236,853 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl424,222,500 - 24,232,017 (+)Ensemblrn6Rnor6.0
Rnor_5.0423,609,795 - 24,155,906 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4423,229,255 - 23,773,114 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera422,087,490 - 22,618,496 (+)NCBICelera
Cytogenetic Map4q12NCBI
ZNF804B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38788,759,700 - 89,338,528 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl788,759,700 - 89,338,528 (+)Ensemblhg38GRCh38
GRCh37788,389,014 - 88,967,842 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36788,226,689 - 88,804,282 (+)NCBIBuild 36Build 36hg18NCBI36
Celera783,093,566 - 83,671,109 (+)NCBICelera
Cytogenetic Map7q21.13NCBI
HuRef782,997,966 - 83,576,194 (+)NCBIHuRef
CHM1_1788,318,791 - 88,896,440 (+)NCBICHM1_1
T2T-CHM13v2.0790,010,335 - 90,589,208 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2787,719,860 - 88,297,487 (+)NCBI
Zfp804b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3956,819,030 - 7,394,378 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl56,819,010 - 7,394,756 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3856,769,030 - 7,344,378 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl56,769,010 - 7,344,756 (-)Ensemblmm10GRCm38
MGSCv3756,769,030 - 7,344,378 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3656,806,674 - 6,828,724 (-)NCBIMGSCv36mm8
Celera56,702,198 - 7,273,135 (-)NCBICelera
Cytogenetic Map5A1NCBI
cM Map53.2NCBI
Znf804b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554326,108,515 - 6,643,567 (+)Ensembl
ChiLan1.0NW_0049554326,108,515 - 6,643,567 (+)NCBIChiLan1.0ChiLan1.0
ZNF804B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26106,630,596 - 107,220,970 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17154,895,234 - 155,485,609 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0780,752,010 - 81,333,608 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1794,400,426 - 94,982,625 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl794,860,215 - 94,981,135 (+)EnsemblpanPan2panpan1.1
ZNF804B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11414,745,733 - 15,248,818 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1414,745,748 - 15,247,067 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1414,317,822 - 14,819,508 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01414,555,859 - 15,051,655 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1414,555,952 - 15,050,852 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11414,720,836 - 15,216,585 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01414,441,096 - 14,934,568 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01414,726,353 - 15,220,658 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Znf804b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511828,747,412 - 28,834,994 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366214,534,215 - 4,621,251 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF804B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl968,983,827 - 69,497,001 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1968,983,529 - 69,500,385 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2975,921,139 - 75,930,892 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF804B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12159,616,629 - 60,193,801 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604243,933,570 - 44,510,189 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf804b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248093,937,424 - 4,080,891 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Zfp804b
5234 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:22
Interacting mature miRNAs:24
Transcripts:ENSRNOT00000045346
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4127716890Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
70222Eae2Experimental allergic encephalomyelitis QTL 24.3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)42133334339505420Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4130372989Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4994088544463908Rat
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4127716890Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
8552803Bw144Body weight QTL 14416body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)42271068534430484Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4131934116Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4127716890Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4129494328Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41794699962946999Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
1358201Gluco12Glucose level QTL121.6adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake (CMO:0000870)4521839229593287Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4132584199Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4131934116Rat
1354665Stl10Serum triglyceride level QTL 103.57blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42133334344463908Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41002490139524530Rat

Markers in Region
D4Rat9  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8427,862,204 - 27,862,366 (+)Marker Load Pipeline
mRatBN7.2426,907,285 - 26,907,447 (+)MAPPERmRatBN7.2
Rnor_6.0423,991,721 - 23,991,882NCBIRnor6.0
Rnor_5.0423,916,923 - 23,917,084UniSTSRnor5.0
RGSC_v3.4423,537,363 - 23,537,525RGDRGSC3.4
RGSC_v3.4423,537,364 - 23,537,525UniSTSRGSC3.4
Celera422,378,595 - 22,378,756UniSTS
RGSC_v3.1423,537,364 - 23,537,525RGD
RH 3.4 Map4160.7RGD
RH 3.4 Map4160.7UniSTS
RH 2.0 Map4172.2RGD
SHRSP x BN Map410.2799RGD
FHH x ACI Map413.41RGD
Cytogenetic Map4q12UniSTS
D4Got204  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2427,100,225 - 27,100,375 (+)MAPPERmRatBN7.2
Rnor_6.0424,186,031 - 24,186,180NCBIRnor6.0
Rnor_5.0424,110,856 - 24,111,005UniSTSRnor5.0
RGSC_v3.4423,731,251 - 23,731,400UniSTSRGSC3.4
Cytogenetic Map4q12UniSTS
AU047210  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2427,100,210 - 27,100,378 (+)MAPPERmRatBN7.2
Rnor_6.0424,186,016 - 24,186,183NCBIRnor6.0
Rnor_5.0424,110,841 - 24,111,008UniSTSRnor5.0
RGSC_v3.4423,731,236 - 23,731,403UniSTSRGSC3.4
Cytogenetic Map4q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
3 3 4 112 35 31 29 29 92 7 1 109 50 61 2 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000045346   ⟹   ENSRNOP00000044493
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl427,564,465 - 28,097,319 (+)Ensembl
mRatBN7.2 Ensembl426,609,744 - 27,141,673 (+)Ensembl
Rnor_6.0 Ensembl424,222,500 - 24,232,017 (+)Ensembl
RefSeq Acc Id: XM_008762730   ⟹   XP_008760952
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8427,563,948 - 28,099,625 (+)NCBI
mRatBN7.2426,608,510 - 27,144,717 (+)NCBI
Rnor_6.0423,678,899 - 24,236,853 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008760952 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000044493
  ENSRNOP00000044493.5
RefSeq Acc Id: XP_008760952   ⟸   XM_008762730
- UniProtKB: F1M1B9 (UniProtKB/TrEMBL),   A6K251 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000044493   ⟸   ENSRNOT00000045346
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M1B9-F1-model_v2 AlphaFold F1M1B9 1-1264 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1589640 AgrOrtholog
BioCyc Gene G2FUF-45812 BioCyc
Ensembl Genes ENSRNOG00000031306 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045346 ENTREZGENE
  ENSRNOT00000045346.5 UniProtKB/TrEMBL
InterPro ZnF-G_patch_domain UniProtKB/TrEMBL
  Znf_C2H2_jaz UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report rno:499994 UniProtKB/TrEMBL
NCBI Gene 499994 ENTREZGENE
PANTHER ZINC FINGER PROTEIN 804B UniProtKB/TrEMBL
  ZINC FINGER-CONTAINING UniProtKB/TrEMBL
Pfam zf-C2H2_jaz UniProtKB/TrEMBL
PhenoGen Zfp804b PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031306 RatGTEx
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A6K251 ENTREZGENE, UniProtKB/TrEMBL
  F1M1B9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-09 Zfp804b  zinc finger protein 804B  LOC499994  hypothetical LOC499994  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC499994  hypothetical LOC499994      Symbol and Name status set to provisional 70820 PROVISIONAL