Eloa2l (elongin A2 like) - Rat Genome Database

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Gene: Eloa2l (elongin A2 like) Rattus norvegicus
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Symbol: Eloa2l
Name: elongin A2 like
RGD ID: 1586821
Description: Orthologous to human ELOA3DP (elongin A3 family member D, pseudogene); INTERACTS WITH benzo[a]pyrene (ortholog); copper(II) sulfate (ortholog); methylisothiazolinone (ortholog).
Type: protein-coding
RefSeq Status: PREDICTED
Previously known as: hypothetical protein LOC683469; LOC306312; LOC683469; similar to RNA polymerase II transcription factor SIII subunit A2; similar to RNA polymerase II transcription factor SIII subunit A2 (Elongin A2) (EloA2) (Transcription elongation factor B polypeptide 3B); uncharacterized protein LOC683469
RGD Orthologs
Human
Bonobo
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81614,096,161 - 14,098,105 (+)NCBIGRCr8
mRatBN7.21614,074,514 - 14,076,458 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1614,074,514 - 14,076,457 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1614,100,102 - 14,102,047 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01615,219,163 - 15,221,108 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01614,152,999 - 14,154,944 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01615,105,838 - 15,111,585 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1615,105,839 - 15,111,585 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01615,004,317 - 15,010,064 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41614,532,911 - 14,535,738 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1614,336,793 - 14,338,732 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Eloa2l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81614,096,161 - 14,098,105 (+)NCBIGRCr8
mRatBN7.21614,074,514 - 14,076,458 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1614,074,514 - 14,076,457 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1614,100,102 - 14,102,047 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01615,219,163 - 15,221,108 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01614,152,999 - 14,154,944 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01615,105,838 - 15,111,585 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1615,105,839 - 15,111,585 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01615,004,317 - 15,010,064 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41614,532,911 - 14,535,738 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1614,336,793 - 14,338,732 (+)NCBICelera
Cytogenetic Map16p14NCBI
ELOA3P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381847,028,021 - 47,030,461 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1847,028,202 - 47,029,842 (-)EnsemblGRCh38hg38GRCh38
GRCh371844,554,573 - 44,556,449 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361842,808,571 - 42,810,447 (-)NCBINCBI36Build 36hg18NCBI36
Build 341842,808,570 - 42,810,211NCBI
Celera1841,350,189 - 41,350,739 (-)NCBICelera
Cytogenetic Map18q21.1NCBI
HuRef1841,402,609 - 41,404,485 (-)NCBIHuRef
CHM1_11844,471,907 - 44,473,789 (-)NCBICHM1_1
ELOA3P
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21764,561,656 - 64,563,898 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11850,254,255 - 50,255,892 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01840,413,752 - 40,417,154 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3

Variants

.
Variants in Eloa2l
10 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:29
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000060703
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)16285170915884239Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760916039848Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16422773017696785Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 8 3 4 3 1 1 1 2 5 1
Below cutoff 3 17 8 8 8 7 7 26 21 15 3 7

Sequence


RefSeq Acc Id: ENSRNOT00000060703   ⟹   ENSRNOP00000058803
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1613,635,661 - 13,637,605 (-)Ensembl
Rnor_6.0 Ensembl1615,105,839 - 15,111,585 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111080   ⟹   ENSRNOP00000077017
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1614,074,514 - 14,076,457 (+)Ensembl
RefSeq Acc Id: NM_001115040   ⟹   NP_001108512
RefSeq Status: PREDICTED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81614,096,161 - 14,098,105 (+)NCBI
mRatBN7.21614,074,514 - 14,076,458 (+)NCBI
Rnor_6.01615,105,838 - 15,111,585 (-)NCBI
Rnor_5.01615,004,317 - 15,010,064 (-)NCBI
RGSC_v3.41614,532,911 - 14,535,738 (+)RGD
Celera1614,336,793 - 14,338,732 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001108512 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58600 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000077017
  ENSRNOP00000077017.1
  ENSRNOP00000092968.1
RefSeq Acc Id: NP_001108512   ⟸   NM_001115040
- UniProtKB: B0BMX4 (UniProtKB/TrEMBL),   A0A8I6AFE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000058803   ⟸   ENSRNOT00000060703
RefSeq Acc Id: ENSRNOP00000077017   ⟸   ENSRNOT00000111080

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586821 AgrOrtholog
BioCyc Gene G2FUF-11964 BioCyc
Ensembl Genes ENSRNOG00000039601 Ensembl
  ENSRNOG00000063161 UniProtKB/TrEMBL
  ENSRNOG00000066342 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000111080 ENTREZGENE
  ENSRNOT00000111080.1 UniProtKB/TrEMBL
  ENSRNOT00000114878.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7129113 IMAGE-MGC_LOAD
KEGG Report rno:683469 UniProtKB/TrEMBL
MGC_CLONE MGC:187449 IMAGE-MGC_LOAD
NCBI Gene 683469 ENTREZGENE
PANTHER ELONGIN-A UniProtKB/TrEMBL
  TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 UniProtKB/TrEMBL
PhenoGen Eloa2l PhenoGen
RatGTEx ENSRNOG00000039601 RatGTEx
  ENSRNOG00000066342 RatGTEx
  ENSRNOG00000067535 RatGTEx
  ENSRNOG00000067867 RatGTEx
UniProt A0A8I6AFE6 ENTREZGENE, UniProtKB/TrEMBL
  B0BMX4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-04-14 Eloa2l  elongin A2 like  LOC683469  similar to RNA polymerase II transcription factor SIII subunit A2  Name and Symbol changed 629549 APPROVED
2020-08-13 LOC683469  similar to RNA polymerase II transcription factor SIII subunit A2  LOC683469  similar to RNA polymerase II transcription factor SIII subunit A2 (Elongin A2) (EloA2) (Transcription elongation factor B polypeptide 3B)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 LOC683469  similar to RNA polymerase II transcription factor SIII subunit A2 (Elongin A2) (EloA2) (Transcription elongation factor B polypeptide 3B)  LOC306312  similar to RNA polymerase II transcription factor SIII subunit A2 (Elongin A2) (EloA2) (Transcription elongation factor B polypeptide 3B)  Data merged from RGD:1588555 737654 PROVISIONAL
2006-11-19 LOC306312  similar to RNA polymerase II transcription factor SIII subunit A2 (Elongin A2) (EloA2) (Transcription elongation factor B polypeptide 3B)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC683469  similar to RNA polymerase II transcription factor SIII subunit A2 (Elongin A2) (EloA2) (Transcription elongation factor B polypeptide 3B)      Symbol and Name status set to provisional 70820 PROVISIONAL