Hmgb4l4 (high-mobility group box 4 like 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Hmgb4l4 (high-mobility group box 4 like 4) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Hmgb4l4 (Ensembl: LOC688702)
Name: high-mobility group box 4 like 4 (Ensembl:similar to RIKEN cDNA 1700001F22)
RGD ID: 1585304
Description: Predicted to enable DNA binding activity. Predicted to be located in nucleus.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: high mobility group protein B4-like; LOC317602; LOC688702; RGD1560254; similar to RIKEN cDNA 1700001F22
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X141,861,901 - 141,862,618 (-)NCBIGRCr8
mRatBN7.2X136,825,997 - 136,826,693 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX136,826,039 - 136,826,713 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X141,611,303 - 141,612,079 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X141,636,111 - 141,636,817 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X143,866,366 - 143,866,911 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX132,944,992 - 132,945,746 (-)NCBICelera
Cytogenetic MapXq36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Variants

.
Variants in Hmgb4l4
7 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX112934952138400867Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000091859   ⟹   ENSRNOP00000069792
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX136,826,039 - 136,826,713 (-)Ensembl
RefSeq Acc Id: XM_006257588   ⟹   XP_006257650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X141,861,901 - 141,862,618 (-)NCBI
mRatBN7.2X136,825,997 - 136,826,693 (-)NCBI
Rnor_6.0X141,611,303 - 141,612,079 (-)NCBI
Rnor_5.0X141,636,111 - 141,636,817 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_006257650 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000069792
  ENSRNOP00000069792.2
  ENSRNOP00000087272.1
Reference Protein Sequences
RefSeq Acc Id: XP_006257650   ⟸   XM_006257588
- UniProtKB: A0A0G2JW93 (UniProtKB/TrEMBL),   A0A8I6A6Y4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069792   ⟸   ENSRNOT00000091859
Protein Domains
HMG box

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-888 BioCyc
Ensembl Genes ENSRNOG00000063423 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000067113 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000091859.2 UniProtKB/TrEMBL
  ENSRNOT00000103726.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.10 UniProtKB/TrEMBL
InterPro HMG_box_dom UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/TrEMBL
KEGG Report rno:688702 UniProtKB/TrEMBL
NCBI Gene 688702 ENTREZGENE
PANTHER HIGH MOBILITY GROUP PROTEIN B4 UniProtKB/TrEMBL
  HIGH MOBILITY GROUP PROTEIN DSP1 UniProtKB/TrEMBL
Pfam HMG_box UniProtKB/TrEMBL
  HMG_box_2 UniProtKB/TrEMBL
PhenoGen Hmgb4l4 PhenoGen
PRINTS HIGHMOBLTY12 UniProtKB/TrEMBL
PROSITE HMG_BOX_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000063423 RatGTEx
  ENSRNOG00000067113 RatGTEx
SMART HMG UniProtKB/TrEMBL
Superfamily-SCOP SSF47095 UniProtKB/TrEMBL
UniProt A0A0G2JW93 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A6Y4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Hmgb4l4  high-mobility group box 4 like 4  LOC688702  similar to RIKEN cDNA 1700001F22  Symbol and Name Changed 1299863 APPROVED
2008-07-08 LOC688702  similar to RIKEN cDNA 1700001F22  LOC678973  similar to RIKEN cDNA 1700001F22  Data merged from RGD:1594257 1643240 APPROVED
2008-07-08 LOC688702  similar to RIKEN cDNA 1700001F22  RGD1560254  similar to RIKEN cDNA 1700001F22   Data merged from RGD:1560254 1643240 APPROVED
2008-04-30 RGD1560254  similar to RIKEN cDNA 1700001F22   RGD1560254_predicted  similar to RIKEN cDNA 1700001F22 (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-20 LOC678973  similar to RIKEN cDNA 1700001F22      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC688702  similar to RIKEN cDNA 1700001F22      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1560254_predicted  similar to RIKEN cDNA 1700001F22 (predicted)  LOC317602  similar to RIKEN cDNA 1700001F22  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC317602  similar to RIKEN cDNA 1700001F22      Symbol and Name status set to provisional 70820 PROVISIONAL