Gbp6-ps2 (guanylate binding protein 6, pseudogene 2) - Rat Genome Database

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Gene: Gbp6-ps2 (guanylate binding protein 6, pseudogene 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Gbp6-ps2
Name: guanylate binding protein 6, pseudogene 2
RGD ID: 1584233
Description: Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in cellular response to type II interferon; defense response to Gram-positive bacterium; and defense response to protozoan. Predicted to be active in cytoplasmic vesicle. Orthologous to human GBP4 (guanylate binding protein 4) and GBP7 (guanylate binding protein 7).
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: MODEL
Previously known as: guanylate-binding protein 4-like; guanylate-binding protein 7-like; LOC687532; similar to guanylate binding protein family, member 6
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: Gbp6  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82234,302,483 - 234,333,245 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2234,303,351 - 234,340,188 (-)EnsemblGRCr8
mRatBN7.22231,643,579 - 231,672,818 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2231,643,535 - 231,741,152 (-)EnsemblmRatBN7.2
Rnor_6.02248,603,520 - 248,615,624 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02267,130,013 - 267,139,903 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera2223,656,072 - 223,685,784 (-)NCBICelera
Cytogenetic Map2q44NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Gbp6-ps2
283 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2202029709236904960Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2210956252251712708Rat
8693697Alc36Alcohol consumption QTL 3620.592drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)2219814164239320906Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2214404877251712708Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2204795005249795005Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2214404877251712708Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2218051934251712708Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2192287802237287802Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2214404877251712708Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2196140964251540988Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2214404877251712708Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2205135267250135267Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2221088977243501206Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2220274283249795005Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2203664411248664411Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2214404877251712708Rat
8693622Alc26Alcohol consumption QTL 262.40.667drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)2223810546243965570Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2192287802237287802Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2220274283249795005Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat

Markers in Region
D2Got158  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22231,473,370 - 231,473,592 (+)MAPPERmRatBN7.2
Rnor_6.02248,464,319 - 248,464,540NCBIRnor6.0
Rnor_5.02266,989,445 - 266,989,666UniSTSRnor5.0
RGSC_v3.42240,673,914 - 240,674,136RGDRGSC3.4
RGSC_v3.42240,673,915 - 240,674,136UniSTSRGSC3.4
Celera2223,668,284 - 223,668,512UniSTS
Celera2223,517,025 - 223,517,246UniSTS
RGSC_v3.12240,660,655 - 240,660,876RGD
RH 3.4 Map21580.9RGD
RH 3.4 Map21580.9UniSTS
Cytogenetic Map2q44UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
1 11 14 3 31 23 9 10 7 30 4 4

Sequence


Ensembl Acc Id: ENSRNOT00000104287   ⟹   ENSRNOP00000080935
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2234,303,351 - 234,340,188 (-)Ensembl
mRatBN7.2 Ensembl2231,643,535 - 231,741,152 (-)Ensembl
RefSeq Acc Id: XR_005501366
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82234,302,483 - 234,333,245 (-)NCBI
mRatBN7.22231,643,579 - 231,672,818 (-)NCBI
Protein Sequences
Ensembl Protein ENSRNOP00000080935.1
Ensembl Acc Id: ENSRNOP00000080935   ⟸   ENSRNOT00000104287
Protein Domains
GB1/RHD3-type G

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1584233 AgrOrtholog
BioCyc Gene G2FUF-50986 BioCyc
Ensembl Genes ENSRNOG00000070399 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000104287 ENTREZGENE
  ENSRNOT00000104287.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  Guanylate-binding protein, C-terminal domain UniProtKB/TrEMBL
InterPro G_GB1_RHD3_dom UniProtKB/TrEMBL
  GBP_C UniProtKB/TrEMBL
  Guanylate-bd/ATL_C UniProtKB/TrEMBL
  Guanylate-bd_C_sf UniProtKB/TrEMBL
  Guanylate-bd_N UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene 687532 ENTREZGENE
PANTHER GUANYLATE BINDING PROTEIN UniProtKB/TrEMBL
Pfam GBP UniProtKB/TrEMBL
  GBP_C UniProtKB/TrEMBL
PhenoGen Gbp6-ps2 PhenoGen
PROSITE G_GB1_RHD3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000070399 RatGTEx
Superfamily-SCOP SSF48340 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8I5ZQL6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-10 Gbp6-ps2  guanylate binding protein 6, pseudogene 2  LOC687532  similar to guanylate binding protein family, member 6  Symbol and Name Changed 1299863 APPROVED
2006-11-19 LOC687532  similar to guanylate binding protein family, member 6      Symbol and Name status set to provisional 70820 PROVISIONAL