Dlat-ps1 (dihydrolipoamide S-acetyltransferase, pseudogene 1) - Rat Genome Database

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Gene: Dlat-ps1 (dihydrolipoamide S-acetyltransferase, pseudogene 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Dlat-ps1
Name: dihydrolipoamide S-acetyltransferase, pseudogene 1
RGD ID: 1583609
Description: Predicted to enable dihydrolipoyllysine-residue acetyltransferase activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Predicted to be located in mitochondrial matrix. Predicted to be part of pyruvate dehydrogenase complex.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: MODEL
Previously known as: LOC679881; similar to dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
RGD Orthologs
Alliance Genes
More Info homologs ...
Related Functional Gene: Dlat  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2133,231,211 - 33,233,823 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl133,231,226 - 33,233,129 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0135,867,983 - 35,870,212 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl135,868,009 - 35,869,909 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0137,265,514 - 37,268,824 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4173,379,079 - 3,380,982 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera131,842,277 - 31,845,907 (+)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Variants

.
Variants in Dlat-ps1
10 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:53
Interacting mature miRNAs:53
Transcripts:ENSRNOT00000023010
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
5684999Bss102Bone structure and strength QTL 1025.50.00000072tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)12076315844095856Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
731169Bp153Blood pressure QTL 1530.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13105084033492143Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat

Markers in Region
DLAT  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2133,232,108 - 33,233,092 (+)MAPPERmRatBN7.2
mRatBN7.2133,232,998 - 33,233,092 (+)MAPPERmRatBN7.2
mRatBN7.2850,979,880 - 50,979,975 (-)MAPPERmRatBN7.2
mRatBN7.2133,232,108 - 33,233,702 (+)MAPPERmRatBN7.2
Rnor_6.0135,868,892 - 35,869,875NCBIRnor6.0
Rnor_6.0135,868,892 - 35,870,578NCBIRnor6.0
Rnor_5.0137,266,408 - 37,268,094UniSTSRnor5.0
Rnor_5.0137,266,408 - 37,267,391UniSTSRnor5.0
RGSC_v3.4173,379,962 - 3,380,945UniSTSRGSC3.4
Celera131,843,186 - 31,844,169UniSTS
Cytogenetic Map17p14UniSTS
Cytogenetic Map8q23UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 1 9 7 1 1 2 3 3 2 1
Below cutoff 2 34 13 10 4 10 6 7 36 11 20 7 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000023010
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl133,231,226 - 33,233,129 (+)Ensembl
Rnor_6.0 Ensembl135,868,009 - 35,869,909 (+)Ensembl
RefSeq Acc Id: XR_146726
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera131,842,277 - 31,845,907 (+)NCBI
Sequence:
RefSeq Acc Id: XR_589906
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0135,867,983 - 35,870,212 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-61887 BioCyc
Ensembl Genes ENSRNOG00000017095 Ensembl
NCBI Gene 679881 ENTREZGENE
PhenoGen Dlat-ps1 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-10 Dlat-ps1  dihydrolipoamide S-acetyltransferase, pseudogene 1  LOC679881  similar to dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)  Symbol and Name Changed 1299863 APPROVED
2006-11-19 LOC679881  similar to dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)      Symbol and Name status set to provisional 70820 PROVISIONAL