Serpinb12 (serpin family B member 12) - Rat Genome Database

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Gene: Serpinb12 (serpin family B member 12) Rattus norvegicus
Analyze
Symbol: Serpinb12
Name: serpin family B member 12
RGD ID: 1566382
Description: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be active in cornified envelope and extracellular space. Orthologous to human SERPINB12 (serpin family B member 12); INTERACTS WITH acrylamide; bisphenol A; doxorubicin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC103690041; LOC304692; RGD1566382; serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12; serine (or cysteine) peptidase inhibitor, clade B, member 12; serpin B12; serpin B12-like; serpin peptidase inhibitor, clade B (ovalbumin), member 12; similar to serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 12
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21323,052,448 - 23,083,691 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1323,052,448 - 23,083,691 (+)Ensembl
Rnor_6.01326,970,824 - 26,999,709 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,970,660 - 26,998,357 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01332,119,751 - 32,147,132 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01331,616,215 - 31,619,910 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41313,106,080 - 13,137,360 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1322,909,857 - 22,938,862 (+)NCBICelera
Cytogenetic Map13p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11604408   PMID:23376485   PMID:24029230  


Genomics

Comparative Map Data
Serpinb12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21323,052,448 - 23,083,691 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1323,052,448 - 23,083,691 (+)Ensembl
Rnor_6.01326,970,824 - 26,999,709 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,970,660 - 26,998,357 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01332,119,751 - 32,147,132 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01331,616,215 - 31,619,910 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41313,106,080 - 13,137,360 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1322,909,857 - 22,938,862 (+)NCBICelera
Cytogenetic Map13p11NCBI
SERPINB12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381863,519,110 - 63,569,329 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1863,542,369 - 63,569,329 (+)EnsemblGRCh38hg38GRCh38
GRCh371861,209,602 - 61,236,562 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361859,374,373 - 59,385,224 (+)NCBINCBI36hg18NCBI36
Build 341859,374,372 - 59,385,224NCBI
Celera1857,943,890 - 57,954,746 (+)NCBI
Cytogenetic Map18q21.33NCBI
HuRef1857,923,215 - 57,934,075 (+)NCBIHuRef
CHM1_11861,219,374 - 61,230,454 (+)NCBICHM1_1
T2T-CHM13v2.01863,747,446 - 63,774,441 (+)NCBI
Serpinb12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391106,862,179 - 106,884,810 (+)NCBIGRCm39mm39
GRCm39 Ensembl1106,862,179 - 106,884,810 (+)Ensembl
GRCm381106,934,449 - 106,957,080 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1106,934,449 - 106,957,080 (+)EnsemblGRCm38mm10GRCm38
MGSCv371108,831,026 - 108,853,655 (+)NCBIGRCm37mm9NCBIm37
MGSCv361108,761,996 - 108,784,625 (+)NCBImm8
Celera1109,783,814 - 109,805,887 (+)NCBICelera
Cytogenetic Map1E2.1NCBI
Serpinb12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540247,342,151 - 47,360,030 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540247,338,874 - 47,361,485 (+)NCBIChiLan1.0ChiLan1.0
SERPINB12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11860,227,478 - 60,238,721 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1860,190,661 - 60,240,704 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01856,915,588 - 56,926,603 (+)NCBIMhudiblu_PPA_v0panPan3
SERPINB12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1113,516,993 - 13,539,834 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl113,518,850 - 13,539,956 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha114,476,959 - 14,501,163 (-)NCBI
ROS_Cfam_1.0113,371,247 - 13,395,525 (-)NCBI
ROS_Cfam_1.0 Ensembl113,374,489 - 13,395,606 (-)Ensembl
UMICH_Zoey_3.1113,409,543 - 13,433,747 (-)NCBI
UNSW_CanFamBas_1.0113,338,833 - 13,363,115 (-)NCBI
UU_Cfam_GSD_1.0113,587,695 - 13,611,747 (-)NCBI
Serpinb12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494426,773,996 - 26,791,578 (-)NCBI
SpeTri2.0NW_0049364972,014,871 - 2,024,575 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERPINB12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1158,120,868 - 158,143,128 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11158,120,724 - 158,143,085 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SERPINB12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11816,193,673 - 16,208,866 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1816,194,694 - 16,206,029 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660609,483,861 - 9,496,030 (+)NCBIVero_WHO_p1.0
Serpinb12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247929,326,066 - 9,343,959 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247929,326,061 - 9,344,870 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH135101  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21323,083,416 - 23,083,625 (+)MAPPERmRatBN7.2
Rnor_6.01326,997,804 - 26,998,012NCBIRnor6.0
Rnor_5.01332,146,858 - 32,147,066UniSTSRnor5.0
RGSC_v3.41313,137,086 - 13,137,294UniSTSRGSC3.4
Celera1322,938,588 - 22,938,796UniSTS
Cytogenetic Map13p13UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317027Aia22Adjuvant induced arthritis QTL 222.29joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)13134266636Rat
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13142356786Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
631672Iddm12Insulin dependent diabetes mellitus QTL 122.20.0032blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)13599466834535351Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13599466844807491Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317034Aia9Adjuvant induced arthritis QTL 94.62joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131176653532331607Rat
2317044Aia23Adjuvant induced arthritis QTL 232.3joint integrity trait (VT:0010548)ankle joint diameter (CMO:0002148)131176653532331607Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:136
Count of miRNA genes:107
Interacting mature miRNAs:121
Transcripts:ENSRNOT00000003501
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 6
Low 18 2 2 2 7 1 1
Below cutoff 8 18 4 10 4 1 1 9 21 9 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003501   ⟹   ENSRNOP00000003501
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1323,052,448 - 23,083,691 (+)Ensembl
Rnor_6.0 Ensembl1326,970,896 - 26,998,078 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000061779   ⟹   ENSRNOP00000058493
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1326,463,404 - 26,466,421 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083145   ⟹   ENSRNOP00000075624
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1326,970,660 - 26,998,357 (+)Ensembl
RefSeq Acc Id: NM_001135867   ⟹   NP_001129339
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21323,052,448 - 23,083,691 (+)NCBI
Rnor_6.01326,970,896 - 26,998,078 (+)NCBI
Rnor_5.01332,119,751 - 32,147,132 (+)NCBI
RGSC_v3.41313,106,080 - 13,137,360 (+)RGD
Celera1322,909,857 - 22,938,862 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090656   ⟹   XP_038946584
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21323,070,447 - 23,083,410 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001129339 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946584 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL91752 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001129339   ⟸   NM_001135867
- UniProtKB: D3ZPF9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075624   ⟸   ENSRNOT00000083145
RefSeq Acc Id: ENSRNOP00000003501   ⟸   ENSRNOT00000003501
RefSeq Acc Id: XP_038946584   ⟸   XM_039090656
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000058493   ⟸   ENSRNOT00000061779

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZN36-F1-model_v2 AlphaFold D3ZN36 1-117 view protein structure
AF-D3ZPF9-F1-model_v2 AlphaFold D3ZPF9 1-421 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698753
Promoter ID:EPDNEW_R9278
Type:single initiation site
Name:Serpinb12_1
Description:serpin family B member 12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01326,970,832 - 26,970,892EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566382 AgrOrtholog
BioCyc Gene G2FUF-18599 BioCyc
Ensembl Genes ENSRNOG00000002602 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000047721 Ensembl
Ensembl Protein ENSRNOP00000003501 ENTREZGENE
  ENSRNOP00000003501.4 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003501 ENTREZGENE
  ENSRNOT00000003501.6 UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/TrEMBL
InterPro Protease_inhib_I4_serpin UniProtKB/TrEMBL
  Protease_inhib_I4_serpin_CS UniProtKB/TrEMBL
  Sepin_dom UniProtKB/TrEMBL
  Serpin_sf UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/TrEMBL
KEGG Report rno:304692 UniProtKB/TrEMBL
NCBI Gene 304692 ENTREZGENE
PANTHER Prot_inh_serpin UniProtKB/TrEMBL
Pfam Serpin UniProtKB/TrEMBL
PhenoGen Serpinb12 PhenoGen
PROSITE SERPIN UniProtKB/TrEMBL
SMART SERPIN UniProtKB/TrEMBL
Superfamily-SCOP Prot_inh_serpin UniProtKB/TrEMBL
UniProt D3ZPF9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Serpinb12  serpin family B member 12  LOC103690041  serpin B12-like  Data Merged 737654 PROVISIONAL
2016-04-13 Serpinb12  serpin family B member 12  Serpinb12  serpin peptidase inhibitor, clade B (ovalbumin), member 12  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-08-25 LOC103690041  serpin B12-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2011-01-19 Serpinb12  serpin peptidase inhibitor, clade B (ovalbumin), member 12  Serpinb12  serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Serpinb12  serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12   Serpinb12_predicted  serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Serpinb12_predicted  serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12 (predicted)  RGD1566382_predicted  similar to serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 12 (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1566382_predicted  similar to serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 12 (predicted)  LOC304692  similar to serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 12  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC304692  similar to serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 12      Symbol and Name status set to provisional 70820 PROVISIONAL