Atp5mc2l2 (ATP synthase membrane subunit c locus 2 like 2) - Rat Genome Database

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Gene: Atp5mc2l2 (ATP synthase membrane subunit c locus 2 like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Atp5mc2l2 (Ensembl: AABR07007730.1)
Name: ATP synthase membrane subunit c locus 2 like 2 (Ensembl:similar to ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9))
RGD ID: 1566212
Description: Predicted to enable lipid binding activity and proton transmembrane transporter activity. Predicted to be involved in proton motive force-driven ATP synthesis and proton transmembrane transport. Predicted to be located in mitochondrial membrane. Predicted to be part of proton-transporting ATP synthase complex, coupling factor F(o); INTERACTS WITH ammonium chloride; tetrachloromethane.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP synthase F(0) complex subunit C2, mitochondrial-like; LOC499512; RGD1566212; similar to ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2; similar to ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9); similar to ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8228,571,086 - 28,571,741 (+)NCBIGRCr8
mRatBN7.2226,836,362 - 26,836,853 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl226,836,416 - 26,836,838 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0226,010,452 - 26,086,391 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0245,202,292 - 45,223,190 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4225,947,555 - 25,951,724 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera222,880,092 - 22,900,980 (+)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Atp5mc2l2
9 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631682Bp115Blood pressure QTL 1154.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2137410502Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2141244106Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2788777242804738Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2902351954023519Rat
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)21185206249003364Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000024269   ⟹   ENSRNOP00000094470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl226,836,416 - 26,836,838 (+)Ensembl
RefSeq Acc Id: XM_039103287   ⟹   XP_038959215
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8228,571,086 - 28,571,741 (+)NCBI
mRatBN7.2226,836,362 - 26,836,853 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038959215 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000068783.2
RefSeq Acc Id: XP_038959215   ⟸   XM_039103287
- UniProtKB: A0A0G2JTN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000094470   ⟸   ENSRNOT00000024269
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-54804 BioCyc
Ensembl Genes ENSRNOG00000015320 UniProtKB/TrEMBL
  ENSRNOG00000018045 Ensembl
Ensembl Transcript ENSRNOT00000090051.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.20.10 UniProtKB/TrEMBL
InterPro ATP_synth_F0_csu UniProtKB/TrEMBL
  ATP_synth_F0_csu_DDCD_BS UniProtKB/TrEMBL
  ATP_synth_F0_csu_sf UniProtKB/TrEMBL
  ATPase_proteolipid_c-like_dom UniProtKB/TrEMBL
  F/V-ATP_Csub_sf UniProtKB/TrEMBL
NCBI Gene 499512 ENTREZGENE
PANTHER ATP SYNTHASE F(0) COMPLEX SUBUNIT C2, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR10031 UniProtKB/TrEMBL
Pfam ATP-synt_C UniProtKB/TrEMBL
PhenoGen Atp5mc2l2 PhenoGen
PRINTS ATPASEC UniProtKB/TrEMBL
PROSITE ATPASE_C UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015320 RatGTEx
  ENSRNOG00000018045 RatGTEx
Superfamily-SCOP SSF81333 UniProtKB/TrEMBL
UniProt A0A0G2JTN8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Atp5mc2l2  ATP synthase membrane subunit c locus 2 like 2  RGD1566212  similar to ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)  Symbol and Name Changed 1299863 APPROVED
2011-12-01 RGD1566212  similar to ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)  RGD1566212  similar to ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-06-27 RGD1566212  similar to ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)  RGD1566212  similar to ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1566212  similar to ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2   RGD1566212_predicted  similar to ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1566212_predicted  similar to ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2 (predicted)  LOC499512  similar to ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499512  similar to ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2      Symbol and Name status set to provisional 70820 PROVISIONAL