Yipf6 (Yip1 domain family, member 6) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Yipf6 (Yip1 domain family, member 6) Rattus norvegicus
Analyze
Symbol: Yipf6
Name: Yip1 domain family, member 6
RGD ID: 1566154
Description: Predicted to enable identical protein binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to act upstream of or within intestinal epithelial cell development. Predicted to be located in COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum. Predicted to be active in trans-Golgi network. Orthologous to human YIPF6 (Yip1 domain family member 6); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC116126; similar to RIKEN cDNA A430107J06; YIP1 family member 6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X68,079,754 - 68,091,845 (+)NCBIGRCr8
mRatBN7.2X64,039,602 - 64,051,715 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX64,040,952 - 64,054,702 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX65,524,701 - 65,532,965 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X69,025,050 - 69,033,314 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X66,586,007 - 66,594,271 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X68,625,760 - 68,637,780 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX68,626,185 - 68,637,416 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X69,499,397 - 69,511,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X86,941,818 - 86,950,082 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX64,417,679 - 64,425,943 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:22802641   PMID:28286305  


Genomics

Comparative Map Data
Yipf6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X68,079,754 - 68,091,845 (+)NCBIGRCr8
mRatBN7.2X64,039,602 - 64,051,715 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX64,040,952 - 64,054,702 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX65,524,701 - 65,532,965 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X69,025,050 - 69,033,314 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X66,586,007 - 66,594,271 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X68,625,760 - 68,637,780 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX68,626,185 - 68,637,416 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X69,499,397 - 69,511,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X86,941,818 - 86,950,082 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX64,417,679 - 64,425,943 (+)NCBICelera
Cytogenetic MapXq22NCBI
YIPF6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X68,499,051 - 68,537,282 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX68,498,562 - 68,537,282 (+)EnsemblGRCh38hg38GRCh38
GRCh37X67,718,893 - 67,757,124 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X67,635,611 - 67,669,026 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX68,070,045 - 68,103,397 (+)NCBICelera
Cytogenetic MapXq12-q13.1NCBI
HuRefX61,546,257 - 61,584,629 (+)NCBIHuRef
CHM1_1X67,611,366 - 67,649,863 (+)NCBICHM1_1
T2T-CHM13v2.0X66,932,508 - 66,970,741 (+)NCBIT2T-CHM13v2.0
Yipf6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X97,979,922 - 97,992,627 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX97,979,922 - 97,992,623 (+)EnsemblGRCm39 Ensembl
GRCm38X98,936,316 - 98,949,021 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX98,936,316 - 98,949,017 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X96,133,120 - 96,144,360 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X95,140,500 - 95,151,740 (+)NCBIMGSCv36mm8
CeleraX85,879,308 - 85,890,754 (+)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX43.19NCBI
Yipf6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554758,084,886 - 8,101,624 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554758,085,017 - 8,101,624 (+)NCBIChiLan1.0ChiLan1.0
YIPF6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X68,146,112 - 68,225,060 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X68,149,708 - 68,227,390 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X57,738,236 - 57,815,002 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X67,803,914 - 67,879,812 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX67,803,940 - 67,839,711 (+)Ensemblpanpan1.1panPan2
YIPF6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X53,026,414 - 53,049,619 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX53,026,609 - 53,045,376 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX43,840,826 - 43,864,105 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X53,986,027 - 54,009,311 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX53,986,275 - 54,009,309 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X51,960,734 - 51,984,014 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X53,286,087 - 53,309,366 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X53,213,136 - 53,236,425 (+)NCBIUU_Cfam_GSD_1.0
Yipf6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X49,041,150 - 49,064,654 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936777169,080 - 193,231 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936777169,794 - 193,155 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YIPF6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX54,661,829 - 54,687,976 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X54,661,771 - 54,687,988 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X61,698,587 - 61,724,762 (+)NCBISscrofa10.2Sscrofa10.2susScr3
YIPF6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X58,345,915 - 58,381,517 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX58,346,203 - 58,379,743 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666065186,978 - 267,810 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Yipf6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248911,802,679 - 1,838,666 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248911,802,679 - 1,832,450 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Yipf6
26 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:614
Count of miRNA genes:297
Interacting mature miRNAs:374
Transcripts:ENSRNOT00000008705
Prediction methods:Microtar, Miranda, Pita
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
70221Bp56Blood pressure QTL 564.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X5704214165612192Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 49 33 19 33 5 5 74 35 41 11 5
Low 6 8 8 8 3 6 3
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000008705   ⟹   ENSRNOP00000008705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX64,040,952 - 64,047,933 (+)Ensembl
Rnor_6.0 EnsemblX68,627,329 - 68,635,593 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076699   ⟹   ENSRNOP00000068227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX68,627,313 - 68,637,027 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076795   ⟹   ENSRNOP00000068121
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX64,041,195 - 64,054,702 (+)Ensembl
Rnor_6.0 EnsemblX68,627,329 - 68,632,512 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090942   ⟹   ENSRNOP00000072895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX68,626,185 - 68,637,416 (+)Ensembl
RefSeq Acc Id: NM_001025747   ⟹   NP_001020918
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X68,081,394 - 68,089,658 (+)NCBI
mRatBN7.2X64,041,194 - 64,049,458 (+)NCBI
Rnor_6.0X68,627,329 - 68,635,593 (+)NCBI
Rnor_5.0X69,499,397 - 69,511,418 (+)NCBI
RGSC_v3.4X86,941,818 - 86,950,082 (+)RGD
CeleraX64,417,679 - 64,425,943 (+)RGD
Sequence:
RefSeq Acc Id: XM_006257077   ⟹   XP_006257139
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X68,079,754 - 68,091,845 (+)NCBI
mRatBN7.2X64,039,602 - 64,051,715 (+)NCBI
Rnor_6.0X68,625,760 - 68,637,780 (+)NCBI
Rnor_5.0X69,499,397 - 69,511,418 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099896   ⟹   XP_038955824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X68,081,393 - 68,091,845 (+)NCBI
mRatBN7.2X64,041,181 - 64,051,715 (+)NCBI
RefSeq Acc Id: NP_001020918   ⟸   NM_001025747
- UniProtKB: Q4QQU5 (UniProtKB/Swiss-Prot),   A6IQ61 (UniProtKB/TrEMBL),   A0A8L2Q3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257139   ⟸   XM_006257077
- Peptide Label: isoform X1
- UniProtKB: Q4QQU5 (UniProtKB/Swiss-Prot),   A6IQ61 (UniProtKB/TrEMBL),   A0A8L2Q3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000008705   ⟸   ENSRNOT00000008705
RefSeq Acc Id: ENSRNOP00000072895   ⟸   ENSRNOT00000090942
RefSeq Acc Id: ENSRNOP00000068227   ⟸   ENSRNOT00000076699
RefSeq Acc Id: ENSRNOP00000068121   ⟸   ENSRNOT00000076795
RefSeq Acc Id: XP_038955824   ⟸   XM_039099896
- Peptide Label: isoform X2
Protein Domains
Yip1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4QQU5-F1-model_v2 AlphaFold Q4QQU5 1-236 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701858
Promoter ID:EPDNEW_R12380
Type:multiple initiation site
Name:Yipf6_1
Description:Yip1 domain family, member 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X68,627,316 - 68,627,376EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566154 AgrOrtholog
BioCyc Gene G2FUF-2157 BioCyc
Ensembl Genes ENSRNOG00000006642 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055030947 UniProtKB/Swiss-Prot
  ENSRNOG00060020492 UniProtKB/Swiss-Prot
  ENSRNOG00065016455 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000008705.8 UniProtKB/TrEMBL
  ENSRNOT00000076795 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000076795.3 UniProtKB/Swiss-Prot
  ENSRNOT00055053694 UniProtKB/Swiss-Prot
  ENSRNOT00060035488 UniProtKB/Swiss-Prot
  ENSRNOT00065027387 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7444864 IMAGE-MGC_LOAD
InterPro Yip1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Yip1/4-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:363476 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:116126 IMAGE-MGC_LOAD
NCBI Gene 363476 ENTREZGENE
PANTHER PROTEIN YIPF6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR21236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Yip1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Yipf6 PhenoGen
RatGTEx ENSRNOG00000006642 RatGTEx
  ENSRNOG00055030947 RatGTEx
  ENSRNOG00060020492 RatGTEx
  ENSRNOG00065016455 RatGTEx
UniProt A0A096MJG6_RAT UniProtKB/TrEMBL
  A0A8L2Q3E7 ENTREZGENE, UniProtKB/TrEMBL
  A6IQ61 ENTREZGENE, UniProtKB/TrEMBL
  Q4QQU5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Yipf6  Yip1 domain family, member 6  MGC116126  similar to RIKEN cDNA A430107J06  Symbol and Name updated 1299863 APPROVED
2006-02-09 MGC116126  similar to RIKEN cDNA A430107J06      Symbol and Name status set to provisional 70820 PROVISIONAL