Bpifb3 (BPI fold containing family B, member 3)

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Gene: Bpifb3 (BPI fold containing family B, member 3) Rattus norvegicus

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Symbol:

Bpifb3

Name:

BPI fold containing family B, member 3

RGD ID:

1565613

Description:

Predicted to enable lipid binding activity. Predicted to be located in cytoplasm. Orthologous to human BPIFB3 (BPI fold containing family B member 3); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; aflatoxin B1 (ortholog).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

antimicrobial peptide RYA3; BPI fold-containing family B member 3; ligand-binding protein RYA3; LOC499924; Long palate, lung and nasal epithelium carcinoma associated protein 3; long palate, lung and nasal epithelium carcinoma-associated protein 3; Lplunc3; Potential ligand-binding protein RYA3; Rya3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	162,861,234 - 162,875,850 (+)	NCBI		GRCr8
mRatBN7.2	3	142,401,068 - 142,415,684 (+)	NCBI	mRatBN7.2	mRatBN7.2
UTH_Rnor_SHR_Utx	3	146,302,990 - 146,317,609 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	154,886,817 - 154,901,436 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	152,627,060 - 152,641,660 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	149,401,890 - 149,416,506 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	149,401,890 - 149,416,506 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	155,779,667 - 155,794,283 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	144,303,258 - 144,317,875 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	141,142,203 - 141,156,819 (+)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

glutathione synthetase deficiency (ISO)

glutatione synthetase deficiency with 5-oxoprolinuria (ISO)

hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

dibutyl phthalate (ISO)

lead diacetate (ISO)

resveratrol (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (ISO,ISS)

extracellular region (IEA)

Molecular Function

lipid binding (IEA)

odorant binding (NAS)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Novel genes for potential ligand-binding proteins in subregions of the olfactory mucosa.	Dear TN, etal., EMBO J. 1991 Oct;10(10):2813-9.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12837268	PMID:14739326	PMID:21787333

Genomics

Comparative Map Data

Bpifb3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	162,861,234 - 162,875,850 (+)	NCBI		GRCr8
mRatBN7.2	3	142,401,068 - 142,415,684 (+)	NCBI	mRatBN7.2	mRatBN7.2
UTH_Rnor_SHR_Utx	3	146,302,990 - 146,317,609 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	154,886,817 - 154,901,436 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	152,627,060 - 152,641,660 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	149,401,890 - 149,416,506 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	149,401,890 - 149,416,506 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	155,779,667 - 155,794,283 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	144,303,258 - 144,317,875 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	141,142,203 - 141,156,819 (+)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

BPIFB3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	33,053,903 - 33,073,847 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	33,053,903 - 33,073,847 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	31,641,709 - 31,661,653 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	31,106,891 - 31,125,095 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	20	28,397,115 - 28,415,310 (+)	NCBI		Celera
Cytogenetic Map	20	q11.21	NCBI
HuRef	20	28,430,357 - 28,448,556 (+)	NCBI		HuRef
CHM1_1	20	31,543,370 - 31,561,565 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	34,780,603 - 34,800,582 (+)	NCBI		T2T-CHM13v2.0

Bpifb3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	153,760,118 - 153,774,916 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	153,760,150 - 153,774,916 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	153,918,198 - 153,932,996 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	153,918,230 - 153,932,996 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	153,743,966 - 153,758,732 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	153,609,671 - 153,624,437 (+)	NCBI		MGSCv36	mm8
Celera	2	159,754,119 - 159,769,356 (+)	NCBI		Celera
Cytogenetic Map	2	H1	NCBI
cM Map	2	75.99	NCBI

Bpifb3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	28,192,605 - 28,207,500 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	28,192,359 - 28,208,946 (-)	NCBI	ChiLan1.0	ChiLan1.0

BPIFB3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	38,744,629 - 38,763,203 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	38,737,727 - 38,756,302 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	29,339,270 - 29,359,959 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	30,458,268 - 30,478,127 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	30,458,268 - 30,478,127 (+)	Ensembl	panpan1.1		panPan2

BPIFB3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	22,319,861 - 22,337,914 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	22,319,874 - 22,337,914 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	21,966,999 - 21,983,488 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	23,007,124 - 23,023,599 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	23,007,124 - 23,023,632 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	22,282,712 - 22,299,196 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	22,392,648 - 22,409,110 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	22,823,769 - 22,840,253 (+)	NCBI		UU_Cfam_GSD_1.0

Bpifb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	171,312,622 - 171,326,953 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936485	19,744,007 - 19,758,094 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936485	19,744,010 - 19,758,300 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BPIFB3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	36,577,408 - 36,602,149 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	36,584,608 - 36,602,145 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	41,547,752 - 41,565,335 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BPIFB3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	37,421,378 - 37,442,007 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	37,423,532 - 37,441,765 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	89,462,047 - 89,482,454 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bpifb3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624842	6,229,521 - 6,244,101 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624842	6,229,281 - 6,244,850 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Bpifb3
67 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	55
Count of miRNA genes:	49
Interacting mature miRNAs:	53
Transcripts:	ENSRNOT00000055349
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	130656562	169034231	Rat
1598877	Bp285	Blood pressure QTL 285	1.5	0.03	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	120538241	165538241	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	141074471	169034231	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
2298477	Eau4	Experimental allergic uveoretinitis QTL 4		0.0011	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	3	137398739	169034231	Rat
61335	Bp20	Blood pressure QTL 20	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	141339236	155617360	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
1331726	Bp208	Blood pressure QTL 208	3.129		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141339013	162184794	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	112681431	157681431	Rat
1300173	Rf11	Renal function QTL 11	3.38		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	121056165	145956249	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	131635904	169034231	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	122438700	167438700	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	127162703	168026850	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	118839124	163839124	Rat
619618	Rf3	Renal disease susceptibility QTL 3	6.5	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate to body weight ratio (CMO:0001270)	3	107693393	152693393	Rat
1300159	Kidm4	Kidney mass QTL 4	3.83		kidney mass (VT:0002707)	right kidney wet weight to body weight ratio (CMO:0001953)	3	121056165	157309487	Rat
5686842	Rf59	Renal function QTL 59			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	3	140069424	146976080	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	130193298	161695983	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	130656562	169034231	Rat
8552952	Pigfal13	Plasma insulin-like growth factor 1 level QTL 13			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	138799500	169034231	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	124122556	169034231	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
1	8	8	2	3	8	6	5	1	27	2

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006235352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474050	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000055349 ⟹ ENSRNOP00000052216

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	149,401,890 - 149,416,506 (+)	Ensembl

RefSeq Acc Id:

NM_001109208 ⟹ NP_001102678

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	162,861,234 - 162,875,850 (+)	NCBI
mRatBN7.2	3	142,401,068 - 142,415,684 (+)	NCBI
Rnor_6.0	3	149,401,890 - 149,416,506 (+)	NCBI
Rnor_5.0	3	155,779,667 - 155,794,283 (+)	NCBI
RGSC_v3.4	3	144,303,258 - 144,317,875 (+)	RGD
Celera	3	141,142,203 - 141,156,819 (+)	RGD

Sequence:

show sequence

CCCAGCCCCTGGCTCTCCTTGCAGAAGGAAGGCTTAATTCAGGCCCTCGGGGAAAACCGCAATT
TGCTCCTGACTTGACATACTGACGGGTTTCTGGCGGCTGTGCCCCCTTTGTCTCTCCAAGCTGC
TGTGTGCAGCTGATGATGCCGGGTGTGTACGCCCTGCTTCTGCTCTGGGGCCTGGCCACGCCGT
GTCTGGGGCTGCTTGAGACAGTGGGCACGCTTGCTCGGATTGACAAAGATGAGCTGGGCAAAGC
CATCCAGAACTCCCTAGTTGGGGGTCCCATTCTGCAAAATGTGCTGGGGACCGTGACATCAGTG
AACCAGGGTCTCCTGGGCGCAGGAGGGCTGCTCGGAGGTGGTGGACTGCTGAGCTACGGTGGCC
TCTTTAGTCTTGTGGAGGAACTCTCTGGGTTGAAGATAGAGGAACTAACCTTGCCCACCGTGTC
AATCAAGCTGCTGCCGGGGGTTGGGGTGCAGCTGAGCCTGCACACCAAGCTGGCCGCAGAGGTG
AATGTGTCTTCGAAAGTGGCACTGGGCATGAGCCCTCGGGGGACACCCATCCTTATCCTTAAGC
GCTGCAACACGCTCTTGGGCCACATCAGCCTGACGTCAGGGCTGCTGCCCACACCAATCTTTGG
GCTTGTGGAACAGACACTGTGCAAGGTGCTGCCTGGACTGCTGTGCCCTGTGGTAGACAGTGTG
CTGAGCGTGGTGAATGAGCTCTTAGGAGCTACGCTGAGCCTGGTACCCCTTGGGCCTCTGGGGT
CTGTGGAGTTCACTCTGGCCACACTGCCCCTAATCTCCAACCAGTACATTGAGTTGGATATAAA
TCCCATCGTGAAGAGCATAGCTGGTGATGTCATTGATTTCCCCAAGCCACGCCTCCCAGTCAAG
ATGCCCCCCAAAGAGGACCACACCTCCCAAGTGACTGTCCCACTCTACCTCTTCAACACTGTGT
TTGGGCTCCTGCAAACCAATGGTGCCCTTGACCTGGACATCACCCCTGAGATGGTTCCCAGAAA
TATCCCGCTGACAACTACTGACCTGGCAGCTTTGGCCCCTGAGGCCCTGGGGAAGCTGCCCCCT
GGTCAGCACCTCCTGCTCTCGCTGCGGGTAATGAAGTCACCCATGATCCTGCTGCAGAACAAGA
AGGTCACAGTCTCTATCCCAGTCACCATCCACGTGCTGTCTTCTGTCCCTCAAGGAACTCCTGT
AGCTCTTTTCCAGATGAATGGAGTCATGACTCTAAATGCCCACCTGGTTCCATCCACCACCAAG
CTGCACATATCTCTGTCCTTGGAACGGTTGACTGTCCAGCTGGCCTCCTCCTTTTCCCAACCTT
TTGACGCATCCCGTCTAGAAGAATGGCTCAGTGATGTGGTCCGGGCTGCCTACATGCAGAAGCT
CAATGAACACCTGGAGGTTGGAATACCTCTGCCTAAAATCCTCAACGTCAACTTTGCCAATTCA
GTAGTGGATGTCATTGAGAATGCGGTCGTGCTCACAGTGGCTCCATGAGGCAGTATGACTGCAG
CTCTTCCTGTTCACTAAGAGTCCTATCTGTCTGCCCGCTCTGCCTCAGTTTCCCTCCCAGCATG
CATTGGTGGCAGTATAAGTACTCCTCTCCCACCCAGGCCCACCTTGCCCTCTGTTCCTGTGATT
ATGACTGTTTGGGGATGGGGTTGACTGGACAGCCACAGATCTGCTTCAGAAAGCACACAGCACC
TTGGTTCAGGCCCAGCCTCAATAAACTGACCCTTGGTCTTGTG

hide sequence

RefSeq Acc Id:

XM_006235352 ⟹ XP_006235414

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	162,861,404 - 162,875,850 (+)	NCBI
mRatBN7.2	3	142,402,502 - 142,415,645 (+)	NCBI
Rnor_6.0	3	149,402,071 - 149,416,419 (+)	NCBI
Rnor_5.0	3	155,779,667 - 155,794,283 (+)	NCBI

Sequence:

show sequence

GCTGGGAACCCACCTACAGAGCAGGAGGAACAGGCTGGTGTGCAGCTGATGATGCCGGGTGTGT
ACGCCCTGCTTCTGCTCTGGGGCCTGGCCACGCCGTGTCTGGGGCTGCTTGAGACAGTGGGCAC
GCTTGCTCGGATTGACAAAGATGAGCTGGGCAAAGCCATCCAGAACTCCCTAGTTGGGGGTCCC
ATTCTGCAAAATGTGCTGGGGACCGTGACATCAGTGAACCAGGGTCTCCTGGGCGCAGGAGGGC
TGCTCGGAGGTGGTGGACTGCTGAGCTACGGTGGCCTCTTTAGTCTTGTGGAGGAACTCTCTGG
GTTGAAGATAGAGGAACTAACCTTGCCCACCGTGTCAATCAAGCTGCTGCCGGGGGTTGGGGTG
CAGCTGAGCCTGCACACCAAGGTTAGCCTGCATGGCTCCGGTCCCCTGGTGGGCCTCCTGCAGC
TGGCCGCAGAGGTGAATGTGTCTTCGAAAGTGGCACTGGGCATGAGCCCTCGGGGGACACCCAT
CCTTATCCTTAAGCGCTGCAACACGCTCTTGGGCCACATCAGCCTGACGTCAGGGCTGCTGCCC
ACACCAATCTTTGGGCTTGTGGAACAGACACTGTGCAAGGTGCTGCCTGGACTGCTGTGCCCTG
TGGTAGACAGTGTGCTGAGCGTGGTGAATGAGCTCTTAGGAGCTACGCTGAGCCTGGTACCCCT
TGGGCCTCTGGGGTCTGTGGAGTTCACTCTGGCCACACTGCCCCTAATCTCCAACCAGTACATT
GAGTTGGATATAAATCCCATCGTGAAGAGCATAGCTGGTGATGTCATTGATTTCCCCAAGCCAC
GCCTCCCAGTCAAGATGCCCCCCAAAGAGGACCACACCTCCCAAGTGACTGTCCCACTCTACCT
CTTCAACACTGTGTTTGGGCTCCTGCAAACCAATGGTGCCCTTGACCTGGACATCACCCCTGAG
ATGGTTCCCAGAAATATCCCGCTGACAACTACTGACCTGGCAGCTTTGGCCCCTGAGGCCCTGG
GGAAGCTGCCCCCTGGTCAGCACCTCCTGCTCTCGCTGCGGGTAATGAAGTCACCCATGATCCT
GCTGCAGAACAAGAAGGTCACAGTCTCTATCCCAGTCACCATCCACGTGCTGTCTTCTGTCCCT
CAAGGAACTCCTGTAGCTCTTTTCCAGATGAATGGAGTCATGACTCTAAATGCCCACCTGGTTC
CATCCACCACCAAGCTGCACATATCTCTGTCCTTGGAACGGTTGACTGTCCAGCTGGCCTCCTC
CTTTTCCCAACCTTTTGACGCATCCCGTCTAGAAGAATGGCTCAGTGATGTGGTCCGGGCTGCC
TACATGCAGAAGCTCAATGAACACCTGGAGGTTGGAATACCTCTGCCTAAAATCCTCAACGTCA
ACTTTGCCAATTCAGTAGTGGATGTCATTGAGAATGCGGTCGTGCTCACAGTGGCTCCATGAGG
CAGTATGACTGCAGCTCTTCCTGTTCACTAAGAGTCCTATCTGTCTGCCCGCTCTGCCTCAGTT
TCCCTCCCAGCATGCATTGGTGGCAGTATAAGTACTCCTCTCCCACCCAGGCCCACCTTGCCCT
CTGTTCCTGTGATTATGACTGTTTGGGGATGGGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102678	(Get FASTA)	NCBI Sequence Viewer
	XP_006235414	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL85985	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00055036469
	ENSRNOP00060033197
	ENSRNOP00065035050
GenBank Protein	Q05701	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001102678 ⟸ NM_001109208
- Peptide Label:	precursor
- UniProtKB:	A6KHX0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MMPGVYALLLLWGLATPCLGLLETVGTLARIDKDELGKAIQNSLVGGPILQNVLGTVTSVNQGL LGAGGLLGGGGLLSYGGLFSLVEELSGLKIEELTLPTVSIKLLPGVGVQLSLHTKLAAEVNVSS KVALGMSPRGTPILILKRCNTLLGHISLTSGLLPTPIFGLVEQTLCKVLPGLLCPVVDSVLSVV NELLGATLSLVPLGPLGSVEFTLATLPLISNQYIELDINPIVKSIAGDVIDFPKPRLPVKMPPK EDHTSQVTVPLYLFNTVFGLLQTNGALDLDITPEMVPRNIPLTTTDLAALAPEALGKLPPGQHL LLSLRVMKSPMILLQNKKVTVSIPVTIHVLSSVPQGTPVALFQMNGVMTLNAHLVPSTTKLHIS LSLERLTVQLASSFSQPFDASRLEEWLSDVVRAAYMQKLNEHLEVGIPLPKILNVNFANSVVDV IENAVVLTVAP hide sequence

RefSeq Acc Id:	XP_006235414 ⟸ XM_006235352
- Peptide Label:	isoform X1
- UniProtKB:	Q05701 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MMPGVYALLLLWGLATPCLGLLETVGTLARIDKDELGKAIQNSLVGGPILQNVLGTVTSVNQGL LGAGGLLGGGGLLSYGGLFSLVEELSGLKIEELTLPTVSIKLLPGVGVQLSLHTKVSLHGSGPL VGLLQLAAEVNVSSKVALGMSPRGTPILILKRCNTLLGHISLTSGLLPTPIFGLVEQTLCKVLP GLLCPVVDSVLSVVNELLGATLSLVPLGPLGSVEFTLATLPLISNQYIELDINPIVKSIAGDVI DFPKPRLPVKMPPKEDHTSQVTVPLYLFNTVFGLLQTNGALDLDITPEMVPRNIPLTTTDLAAL APEALGKLPPGQHLLLSLRVMKSPMILLQNKKVTVSIPVTIHVLSSVPQGTPVALFQMNGVMTL NAHLVPSTTKLHISLSLERLTVQLASSFSQPFDASRLEEWLSDVVRAAYMQKLNEHLEVGIPLP KILNVNFANSVVDVIENAVVLTVAP hide sequence

Ensembl Acc Id:

ENSRNOP00000052216 ⟸ ENSRNOT00000055349

Protein Domains

Lipid-binding serum glycoprotein C-terminal Lipid-binding serum glycoprotein N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q05701-F1-model_v2	AlphaFold	Q05701	1-473	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565613	AgrOrtholog
BioCyc Gene	G2FUF-47200	BioCyc
Ensembl Genes	ENSRNOG00000013398	Ensembl
	ENSRNOG00055025838	UniProtKB/Swiss-Prot
	ENSRNOG00060023262	UniProtKB/Swiss-Prot
	ENSRNOG00065024910	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00055044563	UniProtKB/Swiss-Prot
	ENSRNOT00060040224	UniProtKB/Swiss-Prot
	ENSRNOT00065042814	UniProtKB/Swiss-Prot
InterPro	Bactericidal_perm-incr_a/b_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	BPI_fold-BPI/LBP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Lipid-bd_serum_glycop_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Lipid-bd_serum_glycop_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:499924	UniProtKB/TrEMBL
NCBI Gene	499924	ENTREZGENE
PANTHER	BPI FOLD-CONTAINING FAMILY B MEMBER 3	UniProtKB/TrEMBL
	BPI FOLD-CONTAINING FAMILY B MEMBER 4-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR46019:SF5	UniProtKB/Swiss-Prot
Pfam	LBP_BPI_CETP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LBP_BPI_CETP_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Bpifb3	PhenoGen
RatGTEx	ENSRNOG00000013398	RatGTEx
	ENSRNOG00055025838	RatGTEx
	ENSRNOG00060023262	RatGTEx
	ENSRNOG00065024910	RatGTEx
SMART	BPI1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	BPI2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF55394	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A6KHX0	ENTREZGENE, UniProtKB/TrEMBL
	BPIB3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-08-16	Bpifb3	BPI fold containing family B, member 3	Rya3	antimicrobial peptide RYA3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-08-01	Bpifb3	BPI fold containing family B, member 3	Rya3	antimicrobial peptide RYA3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-08-01	Rya3	antimicrobial peptide RYA3	Bpifb3	BPI fold containing family B, member 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-05	Rya3	antimicrobial peptide RYA3	LOC499924	Long palate, lung and nasal epithelium carcinoma associated protein 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	LOC499924	Long palate, lung and nasal epithelium carcinoma associated protein 3			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar