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Gene: Aff2 (AF4/FMR2 family, member 2) Rattus norvegicus
Symbol: Aff2
Name: AF4/FMR2 family, member 2
Description: Predicted to have G-quadruplex RNA binding activity. Predicted to be involved in learning or memory; nuclear speck organization; and regulation of gene expression. Predicted to localize to the nuclear speck. Human ortholog(s) of this gene implicated in fragile X syndrome. Orthologous to human AFF2 (AF4/FMR2 family member 2); INTERACTS WITH bisphenol A; valproic acid; 4,4'-sulfonyldiphenol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: AF4/FMR2 family member 2; LOC293922; RGD1565592; similar to FMR2 protein
Homo sapiens (human) : AFF2 (AF4/FMR2 family member 2)  HGNC  Alliance
Mus musculus (house mouse) : Aff2 (AF4/FMR2 family, member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aff2 (AF4/FMR2 family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AFF2 (AF4/FMR2 family member 2)
Canis lupus familiaris (dog) : AFF2 (AF4/FMR2 family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aff2 (AF4/FMR2 family member 2)
Sus scrofa (pig) : AFF2 (AF4/FMR2 family member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X153,539,951 - 154,051,022 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX153,539,668 - 154,051,181 (-)Ensembl
Rnor_5.01149,265,910 - 149,777,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X155,617,378 - 155,970,597 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1132,967,188 - 133,469,753 (-)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Aff2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1565592
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.