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Gene: Aff2 (AF4/FMR2 family, member 2) Rattus norvegicus
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Symbol: Aff2
Name: AF4/FMR2 family, member 2
Description: Predicted to have G-quadruplex RNA binding activity. Predicted to be involved in learning or memory; nuclear speck organization; and regulation of gene expression. Predicted to localize to the nuclear speck. Human ortholog(s) of this gene implicated in fragile X syndrome. Orthologous to human AFF2 (AF4/FMR2 family member 2); INTERACTS WITH bisphenol A; valproic acid; 4,4'-sulfonyldiphenol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: AF4/FMR2 family member 2; LOC293922; RGD1565592; similar to FMR2 protein
Orthologs:
Homo sapiens (human) : AFF2 (AF4/FMR2 family member 2)  HGNC  Alliance
Mus musculus (house mouse) : Aff2 (AF4/FMR2 family, member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aff2 (AF4/FMR2 family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AFF2 (AF4/FMR2 family member 2)
Canis lupus familiaris (dog) : AFF2 (AF4/FMR2 family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aff2 (AF4/FMR2 family member 2)
Sus scrofa (pig) : AFF2 (AF4/FMR2 family member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X153,539,951 - 154,051,022 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX153,539,668 - 154,051,181 (-)Ensembl
Rnor_5.01149,265,910 - 149,777,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X155,617,378 - 155,970,597 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1132,967,188 - 133,469,753 (-)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Aff2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1565592
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.