LOC361914 (similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12) - Rat Genome Database

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Gene: LOC361914 (similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12) Rattus norvegicus
Analyze
Symbol: LOC361914 (Ensembl: Slc7a12)
Name: similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 (Ensembl:solute carrier family 7 (cationic amino acid transporter, y+ system), member 12)
RGD ID: 1565475
Description: Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport.
Type: protein-coding
Previously known as: hypothetical protein LOC361914; uncharacterized protein LOC361914
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2 Ensembl287,079,749 - 87,146,875 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0288,453,792 - 88,553,113 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl288,453,812 - 88,553,086 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02108,221,919 - 108,325,908 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4288,620,187 - 88,687,967 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera282,856,621 - 82,921,454 (-)NCBICelera
Cytogenetic Map2q23NCBI


References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:126
Count of miRNA genes:91
Interacting mature miRNAs:98
Transcripts:ENSRNOT00000042494
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH131323  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0288,474,867 - 88,475,052NCBIRnor6.0
Rnor_5.02108,242,994 - 108,243,179UniSTSRnor5.0
RGSC_v3.4288,632,578 - 88,632,763UniSTSRGSC3.4
RGSC_v3.4288,632,578 - 88,633,728UniSTSRGSC3.4
Celera282,868,995 - 82,869,180UniSTS
RH 3.4 Map2534.3UniSTS
Cytogenetic Map2q23UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 2
Medium 11
Low 2 8 25 9 18 9 8 8 9 6 8 10 8
Below cutoff 1 2 1 1 1 1 1 2 8 2 1

Sequence


RefSeq Acc Id: ENSRNOT00000042494   ⟹   ENSRNOP00000040882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl288,453,812 - 88,553,086 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000051741   ⟹   ENSRNOP00000050128
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl287,079,749 - 87,146,875 (-)Ensembl
RefSeq Acc Id: NM_001017465   ⟹   NP_001017465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0288,453,792 - 88,553,086 (-)NCBI
Rnor_5.02108,221,919 - 108,325,908 (-)NCBI
RGSC_v3.4288,620,187 - 88,687,967 (-)RGD
Celera282,856,621 - 82,921,454 (-)RGD
Sequence:
RefSeq Acc Id: XM_006232112   ⟹   XP_006232174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0288,453,890 - 88,553,113 (-)NCBI
Rnor_5.02108,221,919 - 108,325,908 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001017465 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232174 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79349 (Get FASTA)   NCBI Sequence Viewer  
  EDM00970 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001017465   ⟸   NM_001017465
- Sequence:
RefSeq Acc Id: XP_006232174   ⟸   XM_006232112
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000040882   ⟸   ENSRNOT00000042494
RefSeq Acc Id: ENSRNOP00000050128   ⟸   ENSRNOT00000051741

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AXS1-F1-model_v2 AlphaFold Q6AXS1 1-478 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691227
Promoter ID:EPDNEW_R1750
Type:single initiation site
Name:LOC361914_1
Description:similar to solute carrier family 7 (cationic amino acid transporter,y+ system), member 12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0288,553,100 - 88,553,160EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSRNOG00000028985 Ensembl
  ENSRNOG00000033830 Ensembl
Gene3D-CATH Amino acid/polyamine transporter I UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7107785 IMAGE-MGC_LOAD
InterPro AA/rel_permease1 UniProtKB/TrEMBL
MGC_CLONE MGC:94806 IMAGE-MGC_LOAD
NCBI Gene 361914 ENTREZGENE
PANTHER AMINO ACID TRANSPORTER UniProtKB/TrEMBL
  ASC-TYPE AMINO ACID TRANSPORTER 2 UniProtKB/TrEMBL
Pfam AA_permease_2 UniProtKB/TrEMBL
PhenoGen LOC361914 PhenoGen
PIRSF AA_transporter UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028985 RatGTEx
  ENSRNOG00000033830 RatGTEx
UniProt Q6AXS1_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-02-09 LOC361914  similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12      Symbol and Name status set to provisional 70820 PROVISIONAL