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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Uckl1 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1616772 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UCKL1 mRNA | CTD | PMID:17942748 | Uckl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1616772 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UCKL1 mRNA | CTD | PMID:17942748 | Uckl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of UCKL1 mRNA | CTD | PMID:33387578 | Uckl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of UCKL1 mRNA | CTD | PMID:21215274 | Uckl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of UCKL1 mRNA] | CTD | PMID:21215274 | Uckl1 | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | RGD:1616772 | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of UCKL1 mRNA | CTD | PMID:26251327 | Uckl1 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of UCKL1 protein | CTD | PMID:34915118 | Uckl1 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | RGD:1616772 | 6480464 | 4,4'-diaminodiphenylmethane results in decreased expression of UCKL1 mRNA | CTD | PMID:18648102 | Uckl1 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | RGD:1616772 | 6480464 | bisphenol S affects the methylation of UCKL1 gene | CTD | PMID:31683443 | Uckl1 | Rat | acrylamide | decreases expression | ISO | RGD:1342858 | 6480464 | Acrylamide results in decreased expression of UCKL1 mRNA | CTD | PMID:32763439 | Uckl1 | Rat | antirheumatic drug | increases expression | ISO | RGD:1342858 | 6480464 | Antirheumatic Agents results in increased expression of UCKL1 mRNA | CTD | PMID:24449571 | Uckl1 | Rat | aristolochic acid A | decreases expression | ISO | RGD:1342858 | 6480464 | aristolochic acid I results in decreased expression of UCKL1 mRNA | CTD | PMID:33212167 | Uckl1 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of UCKL1 gene | CTD | PMID:35440735 | Uckl1 | Rat | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Uckl1 | Rat | beta-lapachone | decreases expression | ISO | RGD:1342858 | 6480464 | beta-lapachone results in decreased expression of UCKL1 mRNA | CTD | PMID:38218311 | Uckl1 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of UCKL1 mRNA | CTD | PMID:25181051 | Uckl1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of UCKL1 mRNA | CTD | PMID:30816183 | Uckl1 | Rat | bisphenol A | increases methylation | ISO | RGD:1616772 | 6480464 | bisphenol A results in increased methylation of UCKL1 promoter | CTD | PMID:27312807 | Uckl1 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of UCKL1 promoter | CTD | PMID:22457795 | Uckl1 | Rat | caffeine | decreases phosphorylation | ISO | RGD:1342858 | 6480464 | Caffeine results in decreased phosphorylation of UCKL1 protein | CTD | PMID:35688186 | Uckl1 | Rat | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Uckl1 | Rat | chlorpyrifos | increases expression | ISO | RGD:1616772 | 6480464 | Chlorpyrifos results in increased expression of UCKL1 mRNA | CTD | PMID:37019170 | Uckl1 | Rat | copper(II) sulfate | decreases expression | ISO | RGD:1342858 | 6480464 | Copper Sulfate results in decreased expression of UCKL1 mRNA | CTD | PMID:19549813 | Uckl1 | Rat | cyclosporin A | increases expression | ISO | RGD:1342858 | 6480464 | Cyclosporine results in increased expression of UCKL1 mRNA | CTD | PMID:25562108 | Uckl1 | Rat | Dibutyl phosphate | affects expression | ISO | RGD:1342858 | 6480464 | di-n-butylphosphoric acid affects the expression of UCKL1 mRNA | CTD | PMID:37042841 | Uckl1 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of UCKL1 mRNA | CTD | PMID:21266533 | Uckl1 | Rat | doxorubicin | decreases expression | ISO | RGD:1342858 | 6480464 | Doxorubicin results in decreased expression of UCKL1 mRNA | CTD | PMID:29803840 | Uckl1 | Rat | formaldehyde | decreases expression | ISO | RGD:1342858 | 6480464 | Formaldehyde results in decreased expression of UCKL1 mRNA | CTD | PMID:23649840 | Uckl1 | Rat | FR900359 | affects phosphorylation | ISO | RGD:1342858 | 6480464 | FR900359 affects the phosphorylation of UCKL1 protein | CTD | PMID:37730182 | Uckl1 | Rat | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Uckl1 | Rat | hydrogen peroxide | increases expression | ISO | RGD:1342858 | 6480464 | Hydrogen Peroxide results in increased expression of UCKL1 mRNA | CTD | PMID:18951874 | Uckl1 | Rat | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Uckl1 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of UCKL1 gene | CTD | PMID:35440735 | Uckl1 | Rat | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of UCKL1 mRNA | CTD | PMID:28801915 | Uckl1 | Rat | obeticholic acid | decreases expression | ISO | RGD:1342858 | 6480464 | obeticholic acid results in decreased expression of UCKL1 mRNA | CTD | PMID:27939613 | Uckl1 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of UCKL1 mRNA | CTD | PMID:33387578 | Uckl1 | Rat | pentachlorophenol | increases expression | ISO | RGD:1616772 | 6480464 | Pentachlorophenol results in increased expression of UCKL1 mRNA | CTD | PMID:23892564 | Uckl1 | Rat | potassium dichromate | decreases expression | ISO | RGD:1342858 | 6480464 | Potassium Dichromate results in decreased expression of UCKL1 protein | CTD | PMID:23718831 | Uckl1 | Rat | senecionine | increases expression | ISO | RGD:1616772 | 6480464 | senecionine results in increased expression of UCKL1 protein | CTD | PMID:35357534 | Uckl1 | Rat | sodium arsenite | decreases expression | ISO | RGD:1342858 | 6480464 | sodium arsenite results in decreased expression of UCKL1 mRNA | CTD | PMID:38568856 | Uckl1 | Rat | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Uckl1 | Rat | titanium dioxide | decreases methylation | ISO | RGD:1616772 | 6480464 | titanium dioxide results in decreased methylation of UCKL1 gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Uckl1 | Rat | toluene | decreases methylation | ISO | RGD:1342858 | 6480464 | Toluene results in decreased methylation of UCKL1 gene | CTD | PMID:26717081 | Uckl1 | Rat | toluene | increases expression | ISO | RGD:1342858 | 6480464 | Toluene results in increased expression of UCKL1 mRNA | CTD | PMID:26717081 | Uckl1 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of UCKL1 mRNA | CTD | PMID:33387578 | Uckl1 | Rat | triptonide | decreases expression | ISO | RGD:1616772 | 6480464 | triptonide results in decreased expression of UCKL1 mRNA | CTD | PMID:33045310 | Uckl1 | Rat | valproic acid | increases methylation | ISO | RGD:1342858 | 6480464 | Valproic Acid results in increased methylation of UCKL1 gene | CTD | PMID:29154799 | Uckl1 | Rat | valproic acid | affects expression | ISO | RGD:1342858 | 6480464 | Valproic Acid affects the expression of UCKL1 mRNA | CTD | PMID:25979313 | |