Pramel34l (PRAME like 34 like) - Rat Genome Database

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Gene: Pramel34l (PRAME like 34 like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Pramel34l (Ensembl: RGD1565129)
Name: PRAME like 34 like (Ensembl:similar to DNA segment, Chr 5, ERATO Doi 577, expressed)
RGD ID: 1565129
Description: Predicted to be involved in several processes, including negative regulation of DNA-templated transcription; negative regulation of apoptotic process; and positive regulation of cell population proliferation. Predicted to be active in cytoplasm. Orthologous to several human genes including PRAMEF1 (PRAME family member 1); PRAMEF10 (PRAME family member 10); and PRAMEF11 (PRAME family member 11); INTERACTS WITH bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC503459; PRAME family member 20-like; RGD1565129; similar to DNA segment, Chr 5, ERATO Doi 577, expressed
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X96,309,483 - 96,310,928 (+)NCBIGRCr8
mRatBN7.2X92,036,766 - 92,038,211 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX92,036,766 - 92,038,211 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X99,250,516 - 99,251,961 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX99,250,516 - 99,251,961 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X99,094,555 - 99,096,000 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X116,085,154 - 116,086,599 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX93,164,823 - 93,166,268 (+)NCBICelera
Cytogenetic MapXq31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Pramel34l
4 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:32
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000039260
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system integumental system musculoskeletal system reproductive system appendage
High
Medium
Low 1
Below cutoff 2 1 1 1 6 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000039260   ⟹   ENSRNOP00000050389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX92,036,766 - 92,038,211 (+)Ensembl
Rnor_6.0 EnsemblX99,250,516 - 99,251,961 (+)Ensembl
RefSeq Acc Id: XM_017602220   ⟹   XP_017457709
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X96,309,483 - 96,310,928 (+)NCBI
mRatBN7.2X92,036,766 - 92,038,211 (+)NCBI
Rnor_6.0X99,250,516 - 99,251,961 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_017457709 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000050389
  ENSRNOP00000050389.3
Reference Protein Sequences
RefSeq Acc Id: XP_017457709   ⟸   XM_017602220
- UniProtKB: D3ZCB3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000050389   ⟸   ENSRNOT00000039260

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZCB3-F1-model_v2 AlphaFold D3ZCB3 1-481 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565129 AgrOrtholog
BioCyc Gene G2FUF-1727 BioCyc
Ensembl Genes ENSRNOG00000024884 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039260 ENTREZGENE
  ENSRNOT00000039260.5 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro L_dom-like UniProtKB/TrEMBL
  PRAME_family UniProtKB/TrEMBL
KEGG Report rno:503459 UniProtKB/TrEMBL
NCBI Gene 503459 ENTREZGENE
PANTHER D5ERTD577E PROTEIN-RELATED UniProtKB/TrEMBL
  SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 UniProtKB/TrEMBL
PhenoGen Pramel34l PhenoGen
PIRSF PRAME UniProtKB/TrEMBL
RatGTEx ENSRNOG00000024884 RatGTEx
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
UniProt D3ZCB3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Pramel34l  PRAME like 34 like  RGD1565129  similar to DNA segment, Chr 5, ERATO Doi 577, expressed  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1565129  similar to DNA segment, Chr 5, ERATO Doi 577, expressed   RGD1565129_predicted  similar to DNA segment, Chr 5, ERATO Doi 577, expressed (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565129_predicted  similar to DNA segment, Chr 5, ERATO Doi 577, expressed (predicted)  LOC503459  similar to DNA segment, Chr 5, ERATO Doi 577, expressed  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC503459  similar to DNA segment, Chr 5, ERATO Doi 577, expressed      Symbol and Name status set to provisional 70820 PROVISIONAL