Ikzf5l1 (IKAROS family zinc finger 5 like 1) - Rat Genome Database

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Gene: Ikzf5l1 (IKAROS family zinc finger 5 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Ikzf5l1 (Ensembl: RGD1564807)
Name: IKAROS family zinc finger 5 like 1 (Ensembl:similar to zinc finger protein, subfamily 1A, 5)
RGD ID: 1564807
Description: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human IKZF5 (IKAROS family zinc finger 5); INTERACTS WITH bisphenol A; vinclozolin.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC290911; RGD1564807; similar to zinc finger protein, subfamily 1A, 5; zinc finger protein Pegasus-like
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21680,733,779 - 80,736,753 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01686,581,173 - 86,584,692 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1686,581,773 - 86,582,984 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01685,954,900 - 85,997,110 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41686,124,295 - 86,125,488 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1678,511,901 - 78,515,422 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)
vinclozolin  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Ikzf5l1
10 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:184
Count of miRNA genes:140
Interacting mature miRNAs:153
Transcripts:ENSRNOT00000057349
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)163775215682752156Rat
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)163775215682752156Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164239634584729064Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165272646484729064Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165272646484729064Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165272646484729064Rat
631525Pia14Pristane induced arthritis QTL 144.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)165571108783402471Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system hemolymphoid system reproductive system respiratory system
High
Medium
Low 14
Below cutoff 1 2 8 11 1

Sequence


RefSeq Acc Id: ENSRNOT00000057349   ⟹   ENSRNOP00000054163
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1686,581,773 - 86,582,984 (-)Ensembl
RefSeq Acc Id: XM_008771418   ⟹   XP_008769640
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21680,733,779 - 80,736,753 (-)NCBI
Rnor_6.01686,581,173 - 86,584,692 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008769640 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_008769640   ⟸   XM_008771418
- Sequence:
RefSeq Acc Id: ENSRNOP00000054163   ⟸   ENSRNOT00000057349

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A484-F1-model_v2 AlphaFold D4A484 1-403 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564807 AgrOrtholog
BioCyc Gene G2FUF-10599 BioCyc
Ensembl Genes ENSRNOG00000031728 Ensembl
NCBI Gene 290911 ENTREZGENE
PhenoGen Ikzf5l1 PhenoGen
RatGTEx ENSRNOG00000031728 RatGTEx


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Ikzf5l1  IKAROS family zinc finger 5 like 1  RGD1564807  similar to zinc finger protein, subfamily 1A, 5  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1564807  similar to zinc finger protein, subfamily 1A, 5   RGD1564807_predicted  similar to zinc finger protein, subfamily 1A, 5 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564807_predicted  similar to zinc finger protein, subfamily 1A, 5 (predicted)  LOC290911  similar to zinc finger protein, subfamily 1A, 5  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC290911  similar to zinc finger protein, subfamily 1A, 5      Symbol and Name status set to provisional 70820 PROVISIONAL