Ankrd7 (ankyrin repeat domain 7) - Rat Genome Database

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Gene: Ankrd7 (ankyrin repeat domain 7) Rattus norvegicus
Analyze
Symbol: Ankrd7
Name: ankyrin repeat domain 7
RGD ID: 1564660
Description: Predicted to act upstream of or within blastocyst hatching. Predicted to be located in centrosome and nucleoplasm. Orthologous to human ANKRD7 (ankyrin repeat domain 7); INTERACTS WITH bisphenol A; flutamide; antirheumatic drug (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ankyrin repeat domain-containing protein 7; LOC502733; RGD1564660; similar to Ankyrin repeat domain protein 7 (Testis-specific protein TSA806)
RGD Orthologs
Human
Mouse
Bonobo
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8448,278,144 - 48,302,622 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl448,284,445 - 48,336,168 (+)EnsemblGRCr8
mRatBN7.2447,312,270 - 47,336,754 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl447,318,420 - 47,336,753 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx452,301,225 - 52,319,746 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0448,222,383 - 48,240,904 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0446,651,055 - 46,683,586 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0445,564,542 - 45,618,932 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl445,567,573 - 45,586,228 (+)Ensemblrn6Rnor6.0
Rnor_5.0443,028,000 - 43,080,491 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4444,686,331 - 44,710,419 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera442,573,887 - 42,602,221 (+)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centrosome  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19277502   PMID:27869233  


Genomics

Comparative Map Data
Ankrd7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8448,278,144 - 48,302,622 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl448,284,445 - 48,336,168 (+)EnsemblGRCr8
mRatBN7.2447,312,270 - 47,336,754 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl447,318,420 - 47,336,753 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx452,301,225 - 52,319,746 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0448,222,383 - 48,240,904 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0446,651,055 - 46,683,586 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0445,564,542 - 45,618,932 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl445,567,573 - 45,586,228 (+)Ensemblrn6Rnor6.0
Rnor_5.0443,028,000 - 43,080,491 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4444,686,331 - 44,710,419 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera442,573,887 - 42,602,221 (+)NCBICelera
Cytogenetic Map4q22NCBI
ANKRD7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387118,224,704 - 118,242,732 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7118,214,669 - 118,496,171 (+)Ensemblhg38GRCh38
GRCh377117,864,758 - 117,882,786 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367117,651,953 - 117,669,982 (+)NCBIBuild 36Build 36hg18NCBI36
Build 347117,458,909 - 117,476,688NCBI
Celera7112,674,150 - 112,692,226 (+)NCBICelera
Cytogenetic Map7q31.31NCBI
HuRef7112,230,622 - 112,248,684 (+)NCBIHuRef
CHM1_17117,798,215 - 117,816,284 (+)NCBICHM1_1
T2T-CHM13v2.07119,540,436 - 119,558,474 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27117,260,122 - 117,278,198 (+)NCBI
Ankrd7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39618,855,830 - 18,879,588 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl618,866,317 - 18,879,585 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38618,855,842 - 18,879,589 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl618,866,318 - 18,879,586 (+)Ensemblmm10GRCm38
MGSCv37618,816,318 - 18,829,586 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36618,816,319 - 18,829,587 (+)NCBIMGSCv36mm8
Celera618,933,452 - 18,948,359 (+)NCBICelera
Cytogenetic Map6A2NCBI
cM Map68.16NCBI
ANKRD7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26155,050,427 - 155,149,083 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan177,050,436 - 7,078,870 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07110,189,898 - 110,209,035 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17122,885,689 - 122,903,383 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7122,885,689 - 122,903,383 (+)EnsemblpanPan2panpan1.1
Ankrd7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511845,616,015 - 45,623,074 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365891,069,112 - 1,106,858 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKRD7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11828,098,184 - 28,109,802 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21829,856,519 - 29,875,674 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ANKRD7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12186,883,543 - 86,901,221 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604216,823,322 - 16,835,076 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Ankrd7
132 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:115
Count of miRNA genes:85
Interacting mature miRNAs:86
Transcripts:ENSRNOT00000032633
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)43952426474726312Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)43950527573892441Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41794699962946999Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43258419952754138Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 10 39 143 68 71 40 81 40 6 261 148 11 126 52 77 31 13 13

Sequence


Ensembl Acc Id: ENSRNOT00000089824   ⟹   ENSRNOP00000075291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl448,284,469 - 48,302,622 (+)Ensembl
mRatBN7.2 Ensembl447,318,420 - 47,336,753 (+)Ensembl
Rnor_6.0 Ensembl445,567,573 - 45,586,228 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146569   ⟹   ENSRNOP00000106487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl448,284,445 - 48,336,168 (+)Ensembl
RefSeq Acc Id: NM_001192012   ⟹   NP_001178941
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8448,284,469 - 48,302,622 (+)NCBI
mRatBN7.2447,318,601 - 47,336,754 (+)NCBI
Rnor_6.0445,567,721 - 45,586,054 (+)NCBI
Rnor_5.0443,028,000 - 43,080,491 (+)NCBI
Celera442,573,887 - 42,602,221 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006236119   ⟹   XP_006236181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8448,278,144 - 48,302,622 (+)NCBI
mRatBN7.2447,312,270 - 47,336,754 (+)NCBI
Rnor_6.0445,564,542 - 45,586,234 (+)NCBI
Rnor_5.0443,028,000 - 43,080,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006236121   ⟹   XP_006236183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8448,278,144 - 48,302,622 (+)NCBI
mRatBN7.2447,312,270 - 47,336,754 (+)NCBI
Rnor_6.0445,564,542 - 45,586,234 (+)NCBI
Rnor_5.0443,028,000 - 43,080,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063286609   ⟹   XP_063142679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8448,278,144 - 48,302,622 (+)NCBI
RefSeq Acc Id: XR_005503309
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8448,278,144 - 48,302,438 (+)NCBI
mRatBN7.2447,312,270 - 47,336,574 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001178941 (Get FASTA)   NCBI Sequence Viewer  
  XP_006236181 (Get FASTA)   NCBI Sequence Viewer  
  XP_006236183 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142679 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM15130 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000075291
  ENSRNOP00000075291.2
RefSeq Acc Id: NP_001178941   ⟸   NM_001192012
- UniProtKB: A0A0G2KA76 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236181   ⟸   XM_006236119
- Peptide Label: isoform X1
- UniProtKB: A0A0G2KA76 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236183   ⟸   XM_006236121
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000075291   ⟸   ENSRNOT00000089824
RefSeq Acc Id: XP_063142679   ⟸   XM_063286609
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000106487   ⟸   ENSRNOT00000146569

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2KA76-F1-model_v2 AlphaFold A0A0G2KA76 1-278 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692896
Promoter ID:EPDNEW_R3420
Type:initiation region
Name:Ankrd7_1
Description:ankyrin repeat domain 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0445,567,606 - 45,567,666EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564660 AgrOrtholog
BioCyc Gene G2FUF-45533 BioCyc
Ensembl Genes ENSRNOG00000055481 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000089824 ENTREZGENE
  ENSRNOT00000089824.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_repeat_domain UniProtKB/TrEMBL
  Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
KEGG Report rno:502733 UniProtKB/TrEMBL
NCBI Gene 502733 ENTREZGENE
PANTHER ANKYRIN REPEAT DOMAIN 36-RELATED UniProtKB/TrEMBL
  ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 7 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
PhenoGen Ankrd7 PhenoGen
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000055481 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
UniProt A0A0G2KA76 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Ankrd7  ankyrin repeat domain 7  RGD1564660_predicted  similar to Ankyrin repeat domain protein 7 (Testis-specific protein TSA806) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564660_predicted  similar to Ankyrin repeat domain protein 7 (Testis-specific protein TSA806) (predicted)  LOC502733  similar to Ankyrin repeat domain protein 7 (Testis-specific protein TSA806)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC502733  similar to Ankyrin repeat domain protein 7 (Testis-specific protein TSA806)      Symbol and Name status set to provisional 70820 PROVISIONAL